Gene Information

Name : Lferr_2418 (Lferr_2418)
Accession : YP_002220821.1
Strain : Acidithiobacillus ferrooxidans ATCC 53993
Genome accession: NC_011206
Putative virulence/resistance : Unknown
Product : N-6 DNA methylase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 2385586 - 2387163 bp
Length : 1578 bp
Strand : -
Note : PFAM: N-6 DNA methylase; KEGG: mhu:Mhun_2789 N-6 DNA methylase

DNA sequence :
ATGCCGCGCGGACCAACCAAAAAGAAGACCGAAGACACCACCAGCCAGAGCCTGGAATCGAAGCTCTGGGCCACCGCCGA
CAAGCTGCGTGGGCATCTGGACGCCGCCGACTACAAGCATGTGGTGCTGGGCCTCATCTTCCTGAAATACATCTCGGACC
GCTTTGCCCAACGCCATGAAGAAATCATTCGGGAAGAAGCAGGGACTTACGCAGCCGAAGACCGAGATGAATACACGGCG
GAAGGCGTGTTCTGGGTACCGGCATCGTCCAGATGGGCAGTGGTGCAAACTGCCGCCAAACAGCCGGACATCGGCAAGCG
CATCGACGGTGCCATGACCGATATCGAGCGGGAAAACCCGCATCTGAAAAACATCCTGCCCAAAGGCTATGCCCGCCCCA
CCCTGGATCAGCGCCGCCTGGGCGAACTGGTGGACCTCATCGGTACCATTGGCCTTGGCACCGCCGAACATCAGGCCCGC
GACACCCTGGGCCGGGTCTACGAGTATTTTCTGGGTCGATTTGCCAGCGCGGAAGGGAAACGGGGTGGCGAGTTCTACAC
CCCGGCATCGGTGGTCAGAACCCTGGTCACCATGCTGGCCCCCTACAAAGGGCGCATCTATGACCCCTGTTGCGGGTCCG
GCGGCATGTTCGTTCAGTCGGAAAAGTTCATCGAGGCCCACGGTGGCAAAGTCGGCGACATCAGCGTCTATGGGGAAGAA
TCCAACCCCAACACCTGGAAGCTGGCCCTCATGAATCTCGCCATTCGCGGCATCGAGGCCGACCTGGGACCGGAAGCGGC
GGACACCTTTCACAAAGACCTGCATCCCGACCTGCGTGCCGATTACATCCTTGCCAACCCGCCCTTCAACATTTCCGATT
GGGGCGGTGACCTGTTGCGGGATGACAAACGCTGGCAGTATGGGATACCGCCCACCGGCAACGCCAACTTCGCCTGGGTG
CAGCACATGGTCCATCACCTGGCACCCTACGGCATCGCGGGCTTCGTGCTGGCGAATGGTTCCATGTCATCCAATACCAG
CGGTGAAGGCGAAATCCGCAAGAACCTCATTGAAGCGGATCTGGTGGACTGCATGGTGGCCATGCCGGGCCAGCTATTCT
ATAGCACCCAGATTCCCGTGTGCCTGTGGTTCCTGGCGAAGAACCGCGATGACGGACGCGGCATGACCGGCAAGGAACTG
TTTGAGCGCACCGGCGAAGTGCTGTTCATCGATGCCCGCAACATGGGCTTCATGGCCGACCGCACCCACCGGGAACTGAC
CGATGAAGACATCCAAAAGATCGCCGACACCTACCACAACTGGCGCGGCGATGGGGACGGGGAATATGCGGATATTCCCG
GTTTCTGTAAGGCGGCCAGTCTGGATGACATCCGCAAGAACGGCCATGTGCTGACACCAGGGCGTTATGTTGGGGCTGCC
GCCAAGGATGATGACGGCGAGCCTTTCGAGGAAAAGATGGACCGACTGACCAAGGAACTGTCCGCGCAGTTGGCGGAAGG
ACGGCGGTTGGAAGACGAGATGCTGAAGAATTTTCGGGTGTTGGGGTATGAACTGTAA

Protein sequence :
MPRGPTKKKTEDTTSQSLESKLWATADKLRGHLDAADYKHVVLGLIFLKYISDRFAQRHEEIIREEAGTYAAEDRDEYTA
EGVFWVPASSRWAVVQTAAKQPDIGKRIDGAMTDIERENPHLKNILPKGYARPTLDQRRLGELVDLIGTIGLGTAEHQAR
DTLGRVYEYFLGRFASAEGKRGGEFYTPASVVRTLVTMLAPYKGRIYDPCCGSGGMFVQSEKFIEAHGGKVGDISVYGEE
SNPNTWKLALMNLAIRGIEADLGPEAADTFHKDLHPDLRADYILANPPFNISDWGGDLLRDDKRWQYGIPPTGNANFAWV
QHMVHHLAPYGIAGFVLANGSMSSNTSGEGEIRKNLIEADLVDCMVAMPGQLFYSTQIPVCLWFLAKNRDDGRGMTGKEL
FERTGEVLFIDARNMGFMADRTHRELTDEDIQKIADTYHNWRGDGDGEYADIPGFCKAASLDDIRKNGHVLTPGRYVGAA
AKDDDGEPFEEKMDRLTKELSAQLAEGRRLEDEMLKNFRVLGYEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 1e-161 61
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 4e-162 61
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 1e-162 61
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 8e-130 51