Gene Information

Name : Lferr_2404 (Lferr_2404)
Accession : YP_002220808.1
Strain : Acidithiobacillus ferrooxidans ATCC 53993
Genome accession: NC_011206
Putative virulence/resistance : Resistance
Product : copper-translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 2370693 - 2372717 bp
Length : 2025 bp
Strand : -
Note : TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: tbd:Tbd

DNA sequence :
ATGGACCACGCGCGACATCAGGAACATGGGATGGGTACCGCTCATCCCGGTGCGCACGGCGGTCACAACCATGCCGCCAT
GATCGCCGATTTTCGGCGACGGTTTTGGGTATCGCTGGCCCTGACGATCCCTATTCTTCTTTTGTCGCCGCTTATCCAGC
ATCTGCTGAGGCTGGAGGCTGCACTTGCCTTTACTGGGTCGTCCTATGTGCTTTTCGCGCTATCGAGCGCGGTGTATTTC
TACGGCGGTTGGCCCTTCCTGAAGGGGTTGTTTGCCGAGCTCAAAACCCGCAAGCCCGCCATGATGACGCTGATCGCCCT
GGCCATCAGTGTGGCCTATTTTTACTCGAGTGCCGTCGTGTTCGGGGTACAGGGTGAAGTGTTCTTCTGGGAACTCGCTA
CGCTGATCGATGTGATGCTGCTCGGCCACTGGATCGAGATGAAATCGGTCATGGGGGCTTCCGGCGCGCTGGAAAAATTG
GTGCAAATGATGCCTTCCGAGGCTCATCTCGTGGCCCCGGAGGGTATGAAAGACGTGCCGGTCGCCAACCTGCAGCGCGG
TGACCGGGTGCTGGTGAAGCCCGGCGAAAAAATCCCTACGGACGGGCGTGTCATCGAGGGACGGACCACCGTCAACCAGG
CCATGCTCACCGGCGAAAGCCAGCCCGTGGAGAAGGGCGGCGGCGACGAAGTGATCGGCGGTTCGGTCAACGGGGAGTCG
AGTATCACCGTCGAGGTCCATAAGACCGGCAGCGAAACCTATCTTTCACAGGTCATCGAGATGGTGCGCCGGGCGCAGGA
GTCCCGCTCCCGGACCCAGGACCTGGCCGACCGCGCGGCCCTGGTGCTGACCCTTACCGCGTTGAGCGTCGGGGGGCTTA
CCCTTGCCATTTGGCTGGTCCTTGGCCAGCACTTCGAGTTTGCCCTGGCCCGCATGGTGACGGTGATGGTGATTGCCTGT
CCCCATGCCCTGGGCCTGGCGATTCCGCTGGTCGTCGCCGTGTCCACCGCCCTGGCGGCGCAGCATGGTCTGCTTATCCG
GGACCGATCTGCTTTTGAGCGGGCGCGCCAACTGCAGGCGGTGGTGTTCGACAAGACCGGGACCTTGACGGAGGGACGGT
TTGGCGTCACGGATGTGGTTGTGCTGGGCGGATACGCCGAAGATGAGGTCGTACGGCTTGCCGCTGCCCTTGAAAGCCAG
TCGGAACACCCCATCGCCGCCGGCATCGTGGCATATGCCAAAGCGAAGGACATCGGCTTCGAGCCTCCCAAGGAATTCAA
GGCCATCCCCGGCAAGGGCGCACAAGCCCTTGTAAATGGGCGCAATGTGAAGGTCGTAAGCCCCGGCTATCTCGAGGAGC
ATGGCCTTGATGTCAGCGATGAGCGGATCGCGGCCTTGGCATCCCAGGGCAAAACCGTCGTATACCTGCTCATCGATGAG
AAACCGGCGGGGGCGGTCGCGCTGGCCGACATCATTCGAGCGGAGTCGCGGGAAGCGCTCGCGCGGCTGAAGGGGATGGG
CGTGCAGGTGATGATGTTGACCGGCGACTCCGCAGCGGTGGCCCGTTGGGTGGCCCAGGAAATGGGGCTGGACGACTATT
TCGCCGAAGTGCTCCCTGGACAAAAGGCGGAGAAGATCAAGGCGGTGCAGGCGCGGGGATTGCGCGTGGCCATGGTTGGC
GACGGTGTCAACGATGCGCCTGCTCTGGTGGAGGCGGATGTCGGGATCGCTATCGGGGCGGGCACGGATGTCGCCATCGA
GTCGGCGGACATCGTGCTGGTTCGCTCCGATCCCCGGGATGTGGCGGCTATCCTGGAACTTTCCCGGGCGACCTATCGCA
AGATGATCCAGAACCTGTGGTGGGGTGCCGGCTACAATATCGTGGCGATCCCCCTTGCTGCCGGAGTGGCTTACAGTATT
GGCCTGGTGCTTTCCCCGGCGGTGGGGGCGGCCCTGATGTCCGTTTCCACGGTGATCGTCGCCATCAACGCCAAGCTCCT
CCAGAGGGTTCGGCTCACCGCCTAG

Protein sequence :
MDHARHQEHGMGTAHPGAHGGHNHAAMIADFRRRFWVSLALTIPILLLSPLIQHLLRLEAALAFTGSSYVLFALSSAVYF
YGGWPFLKGLFAELKTRKPAMMTLIALAISVAYFYSSAVVFGVQGEVFFWELATLIDVMLLGHWIEMKSVMGASGALEKL
VQMMPSEAHLVAPEGMKDVPVANLQRGDRVLVKPGEKIPTDGRVIEGRTTVNQAMLTGESQPVEKGGGDEVIGGSVNGES
SITVEVHKTGSETYLSQVIEMVRRAQESRSRTQDLADRAALVLTLTALSVGGLTLAIWLVLGQHFEFALARMVTVMVIAC
PHALGLAIPLVVAVSTALAAQHGLLIRDRSAFERARQLQAVVFDKTGTLTEGRFGVTDVVVLGGYAEDEVVRLAAALESQ
SEHPIAAGIVAYAKAKDIGFEPPKEFKAIPGKGAQALVNGRNVKVVSPGYLEEHGLDVSDERIAALASQGKTVVYLLIDE
KPAGAVALADIIRAESREALARLKGMGVQVMMLTGDSAAVARWVAQEMGLDDYFAEVLPGQKAEKIKAVQARGLRVAMVG
DGVNDAPALVEADVGIAIGAGTDVAIESADIVLVRSDPRDVAAILELSRATYRKMIQNLWWGAGYNIVAIPLAAGVAYSI
GLVLSPAVGAALMSVSTVIVAINAKLLQRVRLTA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SH0105 YP_252020.1 hypothetical protein Not tested SCCmec Protein 4e-108 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lferr_2404 YP_002220808.1 copper-translocating P-type ATPase BAC0629 Protein 0.0 68
Lferr_2404 YP_002220808.1 copper-translocating P-type ATPase BAC0079 Protein 2e-133 47
Lferr_2404 YP_002220808.1 copper-translocating P-type ATPase BAC0383 Protein 5e-103 45
Lferr_2404 YP_002220808.1 copper-translocating P-type ATPase BAC0101 Protein 2e-88 42