Gene Information

Name : Lferr_2003 (Lferr_2003)
Accession : YP_002220427.1
Strain : Acidithiobacillus ferrooxidans ATCC 53993
Genome accession: NC_011206
Putative virulence/resistance : Unknown
Product : type I restriction-modification system, M subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 2003301 - 2004914 bp
Length : 1614 bp
Strand : -
Note : TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; KEGG: eba:ebA2607 type I site-specific deoxyribonuclease, methylase subunit

DNA sequence :
ATGACCGAACAAAATCAAAAACAATTGGGCAACACCCTCTGGAGCATCGCCGACCAACTGCGCGGGGCGATGGATGCGGA
CGACTTCCGCGACTACATGCTGTCCTTCCTCTTTTTGCGCTACCTCTCCGACAACTACGAGACGGCGGCGAAGAAGGAAC
TGGGGCGCGATTACCCGGATGTGGGCGGCGACGCGCGCAAGGTGCCGCTGGCGCTCTGGTATGCGAACAACGTGGACGAC
ATTCCGGCCTTCGAGAAGCAGATGCGGCGCAAGGTGCATTACGTCATCCAGCCCGCGCACCTCTGGAATAGCATCGCTAA
CCTGGCTCGCACTCAGAACCCGGACCTGCTAGACACCTTGCAGGCTGGCTTCAAATACATAGAGACAGAGTCTTTTGAGA
GCACTTTCCAGGGGCTGTTCTCCGAAATTGATCTGAGCTCGCCCAAGCTGGGCAAGAGCTACAGCGACCGTAACGCCAAG
CTCTGCACCATCATCCAGAAGATCGCCGAAGGGCTGGCGGCGTTCTCCACGAACATCGACGCGCTGGGCGATGCCTACGA
ATACCTGATCGGCCAGTTTGCCGCAGGCAGTGGCAAGAAGGCGGGCGAATTCTACACCCCGCAGCAGATTTCCGACATTC
TTTCCGCCATCGTCACGCTGGACAGCCAGGAGCCGAAAACCGGGACGAAGAAGCGGCTGGACAGCGTGCTGGACTTCGCC
TGCGGCTCCGGCTCGCTGCTGCTGAATGTGCGCAAGAAGGTGAACCAGGCGGGCGGCAGCATCGGCAAAATCTACGGCCA
GGAAAAGAACATCACCACCTACAACCTCGCGCGCATGAACATGCTGCTGCACGGGGTGAAGGACACCGAGTTCGAGATCT
TCCACGGCGACACCCTGCTCAACGAGTGGGACATGCTGCGCGAGCAGAACCCGGCCAGGAAGCCGAGCTTCGACGCCGTC
GTCGCCAACCCGCCTTTCAGCTACCGCTGGGAGCCCACCGACGCGCTGGCCGACGATGTGCGCTTCAAAAGCCACGGCCT
CGCGCCCAAGTCCGCCGCCGACTTTGCCTTCCTGCTGCACGGCTTCCATTATCTGAAAGACGAAGGGGTGATGGCGATCA
TCCTGCCGCACGGGGTGCTGTTCCGGGGCGGGGCCGAGGAACGCATCCGCACCAAACTGCTCAAGGACGGCCATATCGAC
ACCGTCATCGGCTTGCCCGCGAACCTGTTTTATTCCACCGGCATCCCGGTCTGCATCCTCGTGCTGAAGAAGTGCAAGAA
GCCCGACGACGTGCTGTTCATCAACGCCGCAGAGCACTTTGTGAAAGGCAAACGCCAGAACCATCTTTCGGACGAGCACA
TCGCCAAGATCATCGAAACCTACCAGTTCCGCACGGAAGAACCGCGCTACGCCCGCCGCGTGGACATGGCGGAGATTGAG
AAAAACGACTTCAATCTCAATATTTCGCGGTATATCAGCACAGCAGTAGACGAGGAGGAAATTGACCTGACGGCGACGCA
CGCAAACTTGGTGAACATCGAGAAGGCCATCCAGCAAGCGACTGCGAAACACAACGAATTTCTGAAAGAGCTGGGCATGC
CGCTGTTACCTTAG

Protein sequence :
MTEQNQKQLGNTLWSIADQLRGAMDADDFRDYMLSFLFLRYLSDNYETAAKKELGRDYPDVGGDARKVPLALWYANNVDD
IPAFEKQMRRKVHYVIQPAHLWNSIANLARTQNPDLLDTLQAGFKYIETESFESTFQGLFSEIDLSSPKLGKSYSDRNAK
LCTIIQKIAEGLAAFSTNIDALGDAYEYLIGQFAAGSGKKAGEFYTPQQISDILSAIVTLDSQEPKTGTKKRLDSVLDFA
CGSGSLLLNVRKKVNQAGGSIGKIYGQEKNITTYNLARMNMLLHGVKDTEFEIFHGDTLLNEWDMLREQNPARKPSFDAV
VANPPFSYRWEPTDALADDVRFKSHGLAPKSAADFAFLLHGFHYLKDEGVMAIILPHGVLFRGGAEERIRTKLLKDGHID
TVIGLPANLFYSTGIPVCILVLKKCKKPDDVLFINAAEHFVKGKRQNHLSDEHIAKIIETYQFRTEEPRYARRVDMAEIE
KNDFNLNISRYISTAVDEEEIDLTATHANLVNIEKAIQQATAKHNEFLKELGMPLLP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0053 YP_300143.1 type I restriction-modification system methyltransferase subunit Not tested SCC15305cap Protein 2e-100 45
SAR1899 YP_041281.1 type I restriction modification system modification protein Not tested vSa¥â Protein 8e-99 44
SAS1732 YP_043848.1 type I restriction enzyme modification protein Not tested vSa¥â Protein 4e-100 44
hsdM NP_370955.1 type I site-specific deoxyribonuclease LldI chain Not tested vSa¥á Protein 7e-99 44
hsdM NP_646568.1 hypothetical protein Not tested vSa¥â Protein 4e-100 44
hsdM2 YP_186690.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 6e-100 44
SAMSHR1132_03780 YP_005324900.1 putative type I restriction enzyme modification protein Not tested vSa¥á Protein 1e-99 44
SAV1808 NP_372332.1 type I restriction enzyme EcoR124II M protein Not tested vSa¥â Protein 4e-100 44
SAMSHR1132_16570 YP_005326167.1 restriction-modification system, M subunit Not tested vSa¥â Protein 6e-100 44
hsdM NP_373642.1 type I site-specific deoxyribonuclease LldI subunit HsdM Not tested vSa¥á Protein 1e-99 44
SA1626 NP_374915.1 hypothetical protein Not tested vSa¥â Protein 4e-100 44
hsdM1 YP_185366.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 6e-100 44
hsdM YP_001331432.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥á Protein 6e-100 44
hsdM NP_645209.1 type I site-specific deoxyribonuclease LldI chain hsdM Not tested vSa¥á Protein 1e-99 44
ORF6 BAC22943.1 - Not tested etd PI Protein 6e-100 44
hsdM YP_493119.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 6e-100 44
SAS0394 YP_042520.1 restriction enzyme modification protein Not tested vSa¥á Protein 1e-99 44
SAKOR_00415 YP_008490599.1 Type I restriction-modification system methylation subunit Not tested vSa¥á Protein 5e-100 44
SAR0433 YP_039884.1 type I restriction enzyme modification protein Not tested vSa¥á Protein 5e-100 44
SAKOR_01757 YP_008491945.1 Type I restriction-modification system methylation subunit Not tested vSa¥â Protein 7e-100 44
hsdM YP_001332734.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥â Protein 1e-99 44
hsdM YP_494443.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 1e-99 44