Gene Information

Name : Lferr_1638 (Lferr_1638)
Accession : YP_002220067.1
Strain : Acidithiobacillus ferrooxidans ATCC 53993
Genome accession: NC_011206
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1606221 - 1608821 bp
Length : 2601 bp
Strand : -
Note : KEGG: aeh:Mlg_2558 ATPase AAA-2 domain protein; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase

DNA sequence :
ATGCGTACCGACAAACTGACTACCAAATTCCAACAGGCTTTTCAGGATGCTCAGAGTCTTGCGCTGGCGCAGGATCACCA
GCAGATGGAGCCCATCCACTTGCTTGCTGCTTTTCTTGATCAGGAAGGAGGTATCGCTCGGCCACTCCTGTCAAAGGCCG
GCGTGCGGGTCGATGCCCTACGCAACCAGTTGAACCGCGCGCTGGAGTCCATGCCGAAGGTACAAGGGCATCCGGGCGAG
GTGCAGGTGGGCCGCGATCTTACCAATATGCTCAATCTGGCAGACAAGATAGGCCAGAAGCGCGGCGACACGTATATCTC
CACCGAACACTTCCTGCTGGCCTTGATGGACGACAAGGGCGAGGCGGGGCGCCTCCTGAAAGAGGCGGGTGCCACCACCA
AGGATCTGGAACAGGCCGTCCACGATCTGCACGGCGGGGAAAAAATCAATGATGCCAATGCCGAAGAGCAACGTCAGGCA
CTGGAGAAATATACCATTGACTACACCGAACGGGCCAGTCAAGGCAAGCTGGACCCGGTGATCGGCCGTGACGACGAAAT
CCGCCGGACCATTCAGGTATTGCTGCGGCGCAGCAAAAATAATCCGGTGTTGATCGGTGAACCAGGTGTGGGCAAAACCG
CTATTGTCGAGGGCCTGGCACTGCGCTTGATTAATGGCGAAGTGCCCGAATCTTTGCGCGATAAGCGCCTTCTGGGTTTG
GACTTGGGGGCACTGATTGCCGGTGCCAAGTTTCGCGGTGAGTTCGAGGAACGTCTGAAGTCGTTATTGAACGACCTGGA
GAAGAGTGAGGGTAAAATCATTCTTTTTATTGATGAAATTCATACGCTGGTGGGGGCTGGCAAGGCCGAGGGCTCCATGG
ACGCGGGCAATATGCTCAAGCCGGCGCTGGCGCGCGGCGAGTTACATTGCATCGGTGCCACCACACTGGATGAATATCGT
AAATATATTGAAAAAGATGCGGCGCTGGAACGACGTTTCCAGCGGGTGCTGGTGGATGAACCCAGTGTGGAAGACGCCAT
CGCCATTTTGCGTGGCCTGAAAGAACGCTATGAAGCTCATCATGGGGTACGCATTACCGATCCGGCGCTGGTCGCCGCAG
TGCAGCTTTCACACCGCTATATCACCGACCGTAATCTGCCTGACAAAGCCATAGATCTGATGGATGAAGCGGCCTCCCGC
ATCAAGATGGAAATCGATTCCAAACCTCAGGAACTGGATGAACTGGAGCGCCGTATCATTCAGTTGAACATCGAGCGCGT
GGCGCTGGAGAAGGAGAAGGATGAGGCCAGCCGTAAGCGCCTGGATATTCTGCAGGCCCAAATCAAAGAGTCAGATCGAA
AATATCAGGAGCTGGAAGAAGTTTGGAAAGGCGAAAAGCTGGCTATCGAAGGTACCTCACAGATTCAGAAAGAACTGGAT
CGCAAGCGCGTGGAGCTGGACACGGCGCGTCGTGCCAACGACTTGGAGCGTATGGCGGAACTGCAATACAGCTCTATTCC
GGCATTGGAAGCACAGCTCCATGCCGCTGAAATCCATGCGCAATCAGCAGGTTCAGGCGCTAAACCCACGTTGTTGCGCA
CCGAGGTGGGTGAAGAGGAAATCGCCGAAGTGGTGGCCCGCTGGACCGGCATTCCTGTCTCCAAAATGCTGGAGGGTGAA
AAAGAAAAACTCCTCAAGATGGAGGAGCGCCTGCAGGCGCGGGTAGTGGGTCAGAGCGAGGCGGTGGCCGCGGTATCCAA
CGCCATTCGCCGCTCCCGGGCGGGGCTGTCTGACCCCAAGCGTCCCAATGGCTCTTTCCTTTTTCTTGGCCCCACGGGCG
TCGGCAAAACGGAGTTGACCAAGGCCCTTGCCGAATTTCTCTTCGACAGTGAAGACCACCTGGTGCGCATCGACATGAGC
GAATTCATGGAGAAGCATTCGGTGGCACGGCTCATTGGCGCGCCTCCGGGATACGTAGGTTATGAAGAAGGAGGCTATCT
CACTGAAGCCGTGCGGCGCAAACCGTATTCGGTCGTATTGCTGGACGAGGTGGAGAAGGCCCACCCGGAAGTCTTCAATA
TCCTCCTGCAGGTACTGGATGACGGTCGGCTCACCGATGGCCAGGGGCGCACGGTAGATTTCCGCAATACCGTCATCGTC
ATGACTTCCAATCTCGGCTCCGACCGAATTCAGGAATTCAGTCGCAAAGGGGAGTATGACAGTATGCGCGTGGCGGTACT
GGACGTGGTGCAGGATCACTTCCGTCCGGAGTTCCTCAACCGCATTGATGAGCTGGTCATCTTCCGTCCCCTCACCGCGG
TGCAACTCCGTGAGATTACCGGGATTCAGATGGGCTTCCTGCGGTCACGCCTGCGCGAGCGGGATATGGATCTGGTACTC
AGTGATGGCGCACTGGACCATCTGGCCGAGGTCGGTTATGACCCCGTCTACGGCGCTCGCCCCCTGAAAAGGGTGATTCA
GCGGGAGATCGAAAATCCCCTTGCCCAAAAACTCCTGCGTGGTGACTTCGGACCCGGTGAGATTATTGAAGTGGTTCTTG
AAGGAGACCGCTTTACCTTTGTCGGACAGCGGGTGCACTGA

Protein sequence :
MRTDKLTTKFQQAFQDAQSLALAQDHQQMEPIHLLAAFLDQEGGIARPLLSKAGVRVDALRNQLNRALESMPKVQGHPGE
VQVGRDLTNMLNLADKIGQKRGDTYISTEHFLLALMDDKGEAGRLLKEAGATTKDLEQAVHDLHGGEKINDANAEEQRQA
LEKYTIDYTERASQGKLDPVIGRDDEIRRTIQVLLRRSKNNPVLIGEPGVGKTAIVEGLALRLINGEVPESLRDKRLLGL
DLGALIAGAKFRGEFEERLKSLLNDLEKSEGKIILFIDEIHTLVGAGKAEGSMDAGNMLKPALARGELHCIGATTLDEYR
KYIEKDAALERRFQRVLVDEPSVEDAIAILRGLKERYEAHHGVRITDPALVAAVQLSHRYITDRNLPDKAIDLMDEAASR
IKMEIDSKPQELDELERRIIQLNIERVALEKEKDEASRKRLDILQAQIKESDRKYQELEEVWKGEKLAIEGTSQIQKELD
RKRVELDTARRANDLERMAELQYSSIPALEAQLHAAEIHAQSAGSGAKPTLLRTEVGEEEIAEVVARWTGIPVSKMLEGE
KEKLLKMEERLQARVVGQSEAVAAVSNAIRRSRAGLSDPKRPNGSFLFLGPTGVGKTELTKALAEFLFDSEDHLVRIDMS
EFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVVLLDEVEKAHPEVFNILLQVLDDGRLTDGQGRTVDFRNTVIV
MTSNLGSDRIQEFSRKGEYDSMRVAVLDVVQDHFRPEFLNRIDELVIFRPLTAVQLREITGIQMGFLRSRLRERDMDLVL
SDGALDHLAEVGYDPVYGARPLKRVIQREIENPLAQKLLRGDFGPGEIIEVVLEGDRFTFVGQRVH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 3e-90 42
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 7e-97 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 5e-97 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lferr_1638 YP_002220067.1 ATP-dependent chaperone ClpB VFG2076 Protein 3e-99 45