Gene Information

Name : Lferr_1425 (Lferr_1425)
Accession : YP_002219864.1
Strain : Acidithiobacillus ferrooxidans ATCC 53993
Genome accession: NC_011206
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 1380612 - 1382663 bp
Length : 2052 bp
Strand : -
Note : KEGG: eba:p2B17 TraE protein (DNA topoisomerase); TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase type IA central domain protein; SMART: DNA topoisomerase I ATP-binding; DNA topoisomerase I DNA-binding; Toprim sub domain pro

DNA sequence :
ATGAAACTATACATCGCCGAGAAGCCCAGCCTGGGCAAAGGGATCGCCGAGTATTTGCCCGGATCGAAGAGCAAAGGGAA
TGGCTTCATCCAGTGCGGAGTGGATATCGCCGTGACCTGGTGTTTCGGCCATATATTCGAGCAGGAAGAGCCGGACTTCT
ATACGCCTGATGATGTTCCCACCACGCCAAAGGGCAAGAAGAAATGGCGATTTGAGGAACTGCCCATATTTCCTGAGCAA
TGGAAGAAGCGGGCGAAGGATGACGCCAAGGCCCAGATCAAGGTGATCCGGGACCTGCTCAAGAAAGCCTCGTCTGTCGT
CAATGCCGGCGACCCGGACCGAGAGGGTCAGCTGCTGGTGGATGAGGTCCTGGAGGAACTCCGCTGGAAAGGACCAACCC
TGAGGATCTGGCTGGCCGCCCTCGATGAGCAGTCCGTGCGTAAGGCGCTGGCATCGCTCAAGGATAACCAGGACTACCAG
AATCTCCGAAACTCAGCCGAAGCCCGTGCCCGCGCGGACTGGCTCATGGGCATGAATCTCACCCGTGCTTTCACCCTGCG
CAACAGCGGCGCTGGGGTCGTCTCCGTGGGTCGGGTGCAGACGCCGACCTTGGCTCTGGTCGTGGCCCGTGATGAGAAGA
TCGAGCACTTCAAGCCGAAGGACTACTACGTTCCGCGCATCAACGCGGGCTTCTGGGCCACCTGGGAGTTGCGGGAGGAT
TTCGAGGGGGTCGATGCCGAAGGGTATCTCACCGACGGGAAAGCCGCTGACCGGCTGGTATCCCGGGCCAAGGCGGAAGG
CAAGGCGACGGTGAAGGACTTCACCAGCGTGGAAAAGCAGCAGCAGGCCCCATTAGGCTTCTCCCTTGCAGAGTTACAAA
AGGTCTGCTCCGCCAAGCTCGGCATGTCGGCACAAAATGTCCTTGATGCGGCCCAGGCGCTGTACGAGGAGCACAAGGCG
GCGACCTATCCCCGGACCGATTGCCGCTATCTACCGGAAGAACAGCATGGGGATGCCGGACAGATACTGTCCGGCCTAGC
AAAAGCCGGATTTGCGAATCTGGTGAAAGCCGCCGATTCTAACCGAAAGTCGGCCATCTGGAATACGGGCAAAGTGACGG
CGCACCACGCCATCATTCCGACCGGCTCCATGCAGGGCACTATGAGCCCCGCAGTGGCCAAAGTCTACGAGATCATCGTC
CGCTCCTATCTCGCGCAGTTCTATCCGCCCTATGTGTACCGGGCGATCAAGGCCCTACTGACTTGCACCGGCGAGGACTG
GAAGGCGACTGCCAACATCCCGGTCTCCGCAGGCTGGAAAGCCGTGTATGGGATGACCGATGACGATAATGATGACACCC
CCGCCCAGCCGATCCCGGCGCTCAAAAAAGGCCAGGTTCTGACCGTCCAGGATGCAGATGTCCAGGCAAAACAGACCAAG
CCGCCGGCACGATTTACGGATGGGTCGCTCATCGAGGCCATGAGCAACATCCATAAGGTGGTGGAGGATGAGGCCGCCAA
GGCCAAACTCAAGGAAACCTCTGGCCTGGGGACTGAGGCCACCAGGGCTAGCATCATCGAAACACTGCTCACCCGGGGAT
TCATGGAGCGCAAAGGCAAGCAGATCCTCTCCACCCAGGCAGGGCGGGCGCTGGTTCACGCGCTGCCCAAAGACCTCACG
GATCCCGTCCTGACGGCACGCTGCGAAGATGCCCTGTCATCCGTGTCTGAGGGCCGCGTGACGCTACAGCAGTTCGAGGA
AGCCCAGCGCAAATTCGTTTCTCGCATGATCGAAGCAGCCAAGGCAGCGACCATCGCCGTTGGGCAAGCGCGGTCCGCCA
CGAGCGCGCGGGGTAAGGCGTCTACCAGAAAAACGCGGGGCGGCGGACAAAAGGCTGGCCCCGCCTGCCCGGACTGCAAA
AAACCGACCATTACCCTGAAGACCAAGAAAGGCGACGCCTTTTTCAAGTGCGAGGGCTGCCAGTCCTGCTGGTGGCCGGA
CAAGCAGGATGCCAAGAAGGTCGGAACGAAGTGGAGCGAGAAAAAAACATGA

Protein sequence :
MKLYIAEKPSLGKGIAEYLPGSKSKGNGFIQCGVDIAVTWCFGHIFEQEEPDFYTPDDVPTTPKGKKKWRFEELPIFPEQ
WKKRAKDDAKAQIKVIRDLLKKASSVVNAGDPDREGQLLVDEVLEELRWKGPTLRIWLAALDEQSVRKALASLKDNQDYQ
NLRNSAEARARADWLMGMNLTRAFTLRNSGAGVVSVGRVQTPTLALVVARDEKIEHFKPKDYYVPRINAGFWATWELRED
FEGVDAEGYLTDGKAADRLVSRAKAEGKATVKDFTSVEKQQQAPLGFSLAELQKVCSAKLGMSAQNVLDAAQALYEEHKA
ATYPRTDCRYLPEEQHGDAGQILSGLAKAGFANLVKAADSNRKSAIWNTGKVTAHHAIIPTGSMQGTMSPAVAKVYEIIV
RSYLAQFYPPYVYRAIKALLTCTGEDWKATANIPVSAGWKAVYGMTDDDNDDTPAQPIPALKKGQVLTVQDADVQAKQTK
PPARFTDGSLIEAMSNIHKVVEDEAAKAKLKETSGLGTEATRASIIETLLTRGFMERKGKQILSTQAGRALVHALPKDLT
DPVLTARCEDALSSVSEGRVTLQQFEEAQRKFVSRMIEAAKAATIAVGQARSATSARGKASTRKTRGGGQKAGPACPDCK
KPTITLKTKKGDAFFKCEGCQSCWWPDKQDAKKVGTKWSEKKT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 3e-105 41
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 3e-105 41
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 2e-105 41