Gene Information

Name : hemC (SeD_A4327)
Accession : YP_002217871.1
Strain : Salmonella enterica CT_02021853
Genome accession: NC_011205
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 4173657 - 4174598 bp
Length : 942 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTTAGACAATGTTTTAAGAATTGCCACACGCCAAAGTCCCCTTGCGCTTTGGCAGGCACATTATGTCAAAGACGCATT
GATGGCAACCCATCCGGGACTGACGGTAGAACTGGTGCCGATGGTCACACGCGGCGACGTGATTCTCGATACTCCCCTGG
CGAAAGTGGGCGGTAAGGGACTGTTTGTTAAAGAGCTTGAAATCGCGCTGCTGGAAAAACGCGCTGATATCGCCGTGCAC
TCTATGAAAGACGTTCCGGTGGCCTTCCCGGACGGTCTCGGTCTGGTGACCATTTGCGAGCGCGAAGATCCGCGCGACGC
GTTTGTCTCGAATAAATATCACAGTCTGGACGATCTGCCCGCGGGTAGTATCGTCGGGACGTCCAGTTTGCGTCGTCAGT
GTCAACTGGCGGAACGCCGTCCGGACCTCATTATCCGTTCGTTGCGTGGCAACGTTGGCACACGTCTCGGCAAGCTGGAC
AACGGCGATTATGACGCCATTATCCTGGCCGTGGCCGGTCTGAAACGCTTAGGTCTGGAGTCGCGCATTCGCACAGCCTT
GCCGCCCGACGTTTCACTTCCTGCCGTAGGCCAGGGCGCCGTCGGGATTGAGTGTCGTCTTGACGACGCGCGAACACAGG
CGCTGCTCGCACCGTTGAATCACTCGCAAACCGCGCTGCGCGTAACGGCGGAACGCGCTATGAACACCCGCCTGGAAGGC
GGTTGTCAGGTGCCGATTGGCAGCTATGCAGAAATCATCAACGGTGAAATTTGGCTACGCGCGCTGGTTGGCGCGCCGGA
CGGTTCGGTGATGGTGCGCGGCGAACGTCGTGGTTCTCCCGAGCAGGCGGAGCAAATGGGCATCTCGCTTGCAGAGGAAC
TGCTGGAAAACGGCGCACGCGCGATTCTGACGGAAGTTTATAACGGCGAGACGCCCGCATGA

Protein sequence :
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKGLFVKELEIALLEKRADIAVH
SMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLD
NGDYDAIILAVAGLKRLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGARAILTEVYNGETPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-86 61
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-86 61