Gene Information

Name : tkt_2 (VFMJ11_A0773)
Accession : YP_002158322.1
Strain :
Genome accession: NC_011186
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 831501 - 833492 bp
Length : 1992 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGAACCGTAAACATTTAGCTAATGCAATCCGTGCCCTAAGCATGGACGGCGTACAACAAGCAAACTCTGGTCACCCTGG
CGCTCCTATGGGCATGGCTGACATCGCTGAAGTTCTTTGGCGTTCTCACTTAAATCACAACCCAGCAAACCCTGAGTGGG
CTGATCGCGACCGTTTCATTCTTTCAAACGGTCACGGCTCTATGCTGATCTACTCTCTACTTCACCTTTCAGGTTACGAG
TTATCAATTGATGACCTTAAAAACTTCCGTCAACTTCACTCTAAAACTCCGGGTCACCCAGAGTATGGTTACGCACCTGG
TATCGAAACAACTACAGGTCCTCTAGGCCAAGGTATTACCAATGCTGTTGGTATGGCGATGGCTGAAAAAGCATTAGCGG
CACAATTCAACAAAGAAGGCCACGATATCGTTGACCACTTCACTTATACGTTCATGGGTGATGGCTGTCTGATGGAAGGT
ATTTCTCACGAAGCGTGTTCACTTGCTGGTACATTAGGTCTAGGCAAATTAATCGCATTCTGGGATGACAACGGTATCTC
TATCGATGGTGAAGTTGAAGGTTGGTTCTCTGATGACACACCTAAACGCTTTGAAGCGTACGGCTGGCACGTAATTCCAG
CGGTTGACGGTCACGACTCAGACGCTATCAATGCAGCAATTGAAGCGGCAAAAGCCGATCCTCGCCCTACTCTTATTTGT
ACGAAAACTATTATCGGTTTTGGTTCTCCTAACAAACAAGGTACACACGACTGTCACGGTGCTCCACTAGGCGCTGACGA
AATTAAAGCAGCAAAAGCACAATTAGGTTGGGAGCACGGCGCATTTGAAATTCCGCAAGAAGTTTACGCAGAATGGGACG
CGAAAGAAACAGGCGCAGTTAAGGAAGCGTCGTGGAACGAGAAATTTGCAGCTTATGAAGCAGCATACCCAGAACTTGCA
GCCGAATTTACTCGCCGCGTAAACGGTGATTTACCAAAAGAGTGGGAAGAGAAAGCAAATGCAATCATTGCGGATCTTCA
AGCTAACCCAGCAAACATCGCATCACGTAAAGCATCTCAAAACGCATTAGAAGCATTTGGTGCTATGTTACCTGAATTCA
TGGGTGGCTCTGCTGACCTTGCACCATCTAACCTAACAATGTGGTCTGGTTCTAAGTCGCTTGAAGCAAACGACTTCTCT
GGTAACTACATTCATTACGGTGTTCGTGAATTTGGTATGACAGCAATCATGAATGGTATTGCTCTGCACGGTGGTTTCGT
ACCATACGGCGCAACGTTCCTAATGTTCATGGAATACGCTCGTAACGCAATGCGTATGGCTGCACTAATGAAAGTGCAAA
ACATCCAAGTTTACACGCACGACTCTATCGGTCTTGGCGAAGATGGTCCAACTCACCAACCAGTTGAGCAAATCGCTTCT
CTACGTCTAACGCCTAACATGAGCACATGGCGTCCATGTGACCAAGTTGAGTCAGCTGTAGCATGGAAACTAGCTATCGA
GCGTAAAAATGGTCCATCTGCACTTATCTTCTCTCGTCAAAACCTTGCACAACAAGAGCGTGATGCAGAGCAATTAACGA
ACATCGCTAAAGGTGGCTACATCCTTAAAGATTGTGAAGGCCAACCTGAGTTGATCCTTATTGCAACGGGTTCAGAAGTT
GAACTAGCAGTTGAAGCAGCAGCACAACTGACAGCAGAAGGTAAAGTGGTACGTGTTGTTTCAATGCCATCAACAGATGC
ATTTGATAAGCAAGACGAAGCATACCGTGAAGCAGTGCTTCCATCAGCGGTAACTAAACGTATCGCAATTGAAGCGGGTA
TTGCTGATTTCTGGTACAAGTATGTCGGTTTCGGTGGCAAGATCATCGGCATGACAACATTTGGTGAGTCAGCACCTGCT
GATGAGCTATTCAAAATGTTTGGTTTCACTACTGAAAACGTAGTAAACACAGCAAAAGAATTGTTAGCTTAA

Protein sequence :
MNRKHLANAIRALSMDGVQQANSGHPGAPMGMADIAEVLWRSHLNHNPANPEWADRDRFILSNGHGSMLIYSLLHLSGYE
LSIDDLKNFRQLHSKTPGHPEYGYAPGIETTTGPLGQGITNAVGMAMAEKALAAQFNKEGHDIVDHFTYTFMGDGCLMEG
ISHEACSLAGTLGLGKLIAFWDDNGISIDGEVEGWFSDDTPKRFEAYGWHVIPAVDGHDSDAINAAIEAAKADPRPTLIC
TKTIIGFGSPNKQGTHDCHGAPLGADEIKAAKAQLGWEHGAFEIPQEVYAEWDAKETGAVKEASWNEKFAAYEAAYPELA
AEFTRRVNGDLPKEWEEKANAIIADLQANPANIASRKASQNALEAFGAMLPEFMGGSADLAPSNLTMWSGSKSLEANDFS
GNYIHYGVREFGMTAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQPVEQIAS
LRLTPNMSTWRPCDQVESAVAWKLAIERKNGPSALIFSRQNLAQQERDAEQLTNIAKGGYILKDCEGQPELILIATGSEV
ELAVEAAAQLTAEGKVVRVVSMPSTDAFDKQDEAYREAVLPSAVTKRIAIEAGIADFWYKYVGFGGKIIGMTTFGESAPA
DELFKMFGFTTENVVNTAKELLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 78
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 68