Gene Information

Name : VFMJ11_B0053 (VFMJ11_B0053)
Accession : YP_002157415.1
Strain :
Genome accession: NC_011185
Putative virulence/resistance : Unknown
Product : type I restriction-modification system, M subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : 2.1.1.72
Position : 45003 - 46550 bp
Length : 1548 bp
Strand : +
Note : identified by match to protein family HMM PF02384

DNA sequence :
ATGGTTAAAAATGTTGGCGATAAAGCGTTTTTCGATACACTTTGGGATTCAGCGGTAGCACTACGTGGTGCTCTGCAACC
ATCAGAATACAAGCACCCAGTGCTAGGCTTACTGTTTATTAAATACGTAAGTGACTCATTCACTGAACTTCAAGTGAACC
TAAAAGAATGGGTTGCAGACGCAAACCATGATTACTACGGAATGGACATCAACGATCCAGACCTATACGAAGCTGAAAAC
GTATTCTGGGTTCCAGAAGAAGCTCGTTGGGATTTCCTTGTAGGATCTGCAAAACAAACCAACATTGCGAAACTGCTAGA
TGAAGCAGTTAAAGCCATTGAAGACAACAACTCTCAATTGAAAGGCATGTTGTATCGCGGCTTTGGTTTGCTGAAAATTC
CATCATCTAAGCTGGGTGAGTTAATTGACTTGCTAGGTAAGTTGACCTTTAACTCGAAAGAACATCGCTCTGCTGACGTA
CTAGGTCAGGCGTATGAATTCTTCCTTGGTAAGTTCGCTTTGGCGGAGGGAGCCTCGGCTGGCGCTTTCTACACTCCAGA
AAGTATTGTCTCGACTATCGTTGAAGTGATTGCACCAACTAAAGGGCAATTGTATGAGCCAGCAATTGGTTCTGGCGGTA
TGGTTGTGTGTTCTGAAAAGTTCATGGAACGGAACGGTGGTGAACGCGGTGATATTAGTGTGTACGGTCAAGAATATACC
CATACCACTTGGAAGATGGCTGCGATGAACTTGACCATTCGTGGTCTAGATTTTGATTTGGGTAAAGAGAATGCCGATAC
GCTATTAAATGATCTGCACAAAGACCTACGTGCTGATTACATTATGGCTAACCCTCCATTCAACCAAGAGAAATGGGGTG
CAGCAAAAGTAGCAGGTGATGTTCGTTGGAAATGGGGACAACCATCAGATAGCAATGCCAACTACGCTTGGATCCAGCAC
ATGCTTTACCACCTAAACGAAACAGGTCGTGCAGGTGTGGTAATGGCAAATGGTGCAATGACATCAACTGCCAACAACGA
AGATGCTATTCGTAAAGCAATCATTGAAGATGACCTAGTTGAGTGTATGGTTGCTCTGCCACCTAAGTTGTTCATCAATA
CTCAAATTCCATCTTGTATCTTCTTCTTCAACAAGAACAAGAAGCGCAAAGGTGAAACTCTGTTCATCGATGCTCGTCAC
CTTGGTCGCCTAGAAAGCCGTGCTCAGCTTGTTTTTGATGAAGAGCACATCATGGAAATCGCTAACACCTACCATGCATG
GGCTAAGACTGATTTTGCTGAGAAAGATAGCAAATATGTTGATATCGCAGGTTTCTGTAAGTCAGGCAAACTAGAAGATA
TTGAGAAAGCTGGATTTGTGCTATCTCCAGGTCGTTACGTGGGTGCGGCGGAAGTTGAAGAAGATGAAGCTTCATACCAA
GAAGATATGGCTACTTTAACAGGTCAACTATCTGAGCAGATTAAAAAATCAGTTTCACTTGATGAGCAAATTAAAGCTTC
GCTTGCGGAGGTTGGTTATGATATTTGA

Protein sequence :
MVKNVGDKAFFDTLWDSAVALRGALQPSEYKHPVLGLLFIKYVSDSFTELQVNLKEWVADANHDYYGMDINDPDLYEAEN
VFWVPEEARWDFLVGSAKQTNIAKLLDEAVKAIEDNNSQLKGMLYRGFGLLKIPSSKLGELIDLLGKLTFNSKEHRSADV
LGQAYEFFLGKFALAEGASAGAFYTPESIVSTIVEVIAPTKGQLYEPAIGSGGMVVCSEKFMERNGGERGDISVYGQEYT
HTTWKMAAMNLTIRGLDFDLGKENADTLLNDLHKDLRADYIMANPPFNQEKWGAAKVAGDVRWKWGQPSDSNANYAWIQH
MLYHLNETGRAGVVMANGAMTSTANNEDAIRKAIIEDDLVECMVALPPKLFINTQIPSCIFFFNKNKKRKGETLFIDARH
LGRLESRAQLVFDEEHIMEIANTYHAWAKTDFAEKDSKYVDIAGFCKSGKLEDIEKAGFVLSPGRYVGAAEVEEDEASYQ
EDMATLTGQLSEQIKKSVSLDEQIKASLAEVGYDI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 1e-121 50
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 3e-121 50
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 6e-122 50
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 2e-112 46