Gene Information

Name : guaA (VFMJ11_0652)
Accession : YP_002155395.1
Strain :
Genome accession: NC_011184
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 684530 - 686083 bp
Length : 1554 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACGACTAATATCCACGATCAACGTATTCTTATTTTAGATTTTGGTTCTCAATATACGCAGCTTGTTGCGCGTCGTAT
TCGTGAAATCGGTGTTTACTGTGAGCTTTGGAGCTGGGATGTAGAAGAATCTGACATCCGTGATTTTAATCCAGACGGTA
TCATTTTATCTGGTGGCCCTGAGAGTGTTACAGAAGAAAACTCTCCTCGTGCACCACAATATGTATTTGATTCAGGTGTT
CCTGTATTTGGTGTGTGTTACGGCATGCAGACAATGGCAGAGCAACTTGGTGGTAAAGTTGCAACATCAACTGAACGTGA
GTTTGGTTATGCAGCAGTGCAAGTAACAGGTGAATCAGCGTTATTTAAAGATCTTGAAGCAACTCAAGATGTTTGGATGA
GCCACGGTGATAAAGTCGTTGAAATTCCATCTGATTTTGTAAAAATTGCAGAGACTGAAACATGTCCATACGCTGTAATG
GCGAATGAAGAGAAAAAATATTACGGTGTTCAATTCCACCCAGAAGTAACTCACACTAAAAATGGCATGAAAATGCTTGA
GAACTTTGTTCTTAATGTGTGTGGTTGTGAAGGTTTATGGACATCAGCTTCTATTATTGAAGATGCCGTTGCTCGTATTA
AAGAGCAAGTAGGTGATGATGAAGTGATTCTTGGTCTATCTGGTGGCGTTGACTCATCAGTAGTTGCAATGCTTGCTCAC
CGAGCAATTGGTGACAAACTAACGTGTGTATTCGTTGATAACGGTTTACTACGTTTAAATGAAGCTGATCAAGTAATGGA
AATGTTTGGCAACAAATTTGGCCTAAACATTATTCACGTTAATGCTGAACAGCGTTTCCTTGATGCACTAGAAGGTGAGT
CGGATCCTGAAGTAAAGCGTAAGATCATCGGTCACGTATTCGTAGATATCTTTGATGAAGAATCTAAGAAACTGAAAAAT
GCTAAATGGTTAGCACAAGGTACTATCTACCCTGATGTTATTGAATCAGCAGCATCTAAAACAGGTAAAGCACACGTAAT
TAAATCGCACCATAACGTTGGCGGTTTGCCTGATGATATGGAAATGGGGCTTGTTGAGCCTCTACGTGAATTATTTAAAG
ATGAAGTTCGTAAGATCGGTCTAGAACTAGGCTTACCTTATAACATGCTTTACCGCCACCCGTTCCCGGGTCCAGGTTTA
GGTGTTCGTGTTCTTGGTGAAATTAAGAAAGAATACTGTGATTTACTTCGCCGCGCAGATGCTATTTTCATTGAAGAATT
ACACAATGCAGATCTTTATAATAAAGTATCTCAAGCATTCACTGTATTCTTACCAGTTCGTTCTGTTGGTGTAATGGGTG
ACGGTCGTAAGTACGATTGGGTTGTTTCTCTACGTGCTGTTGAGACTATCGACTTTATGACTGCGCATTGGGCACATTTA
CCATACGATTTCTTAGGTAAAGTATCTAACCGTATTATTAATGAAGTTAATGGCATTTCTCGTGTAGTTTACGATATTTC
AGGTAAGCCACCAGCAACAATCGAGTGGGAATAA

Protein sequence :
MTTNIHDQRILILDFGSQYTQLVARRIREIGVYCELWSWDVEESDIRDFNPDGIILSGGPESVTEENSPRAPQYVFDSGV
PVFGVCYGMQTMAEQLGGKVATSTEREFGYAAVQVTGESALFKDLEATQDVWMSHGDKVVEIPSDFVKIAETETCPYAVM
ANEEKKYYGVQFHPEVTHTKNGMKMLENFVLNVCGCEGLWTSASIIEDAVARIKEQVGDDEVILGLSGGVDSSVVAMLAH
RAIGDKLTCVFVDNGLLRLNEADQVMEMFGNKFGLNIIHVNAEQRFLDALEGESDPEVKRKIIGHVFVDIFDEESKKLKN
AKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDDMEMGLVEPLRELFKDEVRKIGLELGLPYNMLYRHPFPGPGL
GVRVLGEIKKEYCDLLRRADAIFIEELHNADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHL
PYDFLGKVSNRIINEVNGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-134 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-134 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-134 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-114 48