Gene Information

Name : tkt_1 (VFMJ11_0440)
Accession : YP_002155196.1
Strain :
Genome accession: NC_011184
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 456385 - 458379 bp
Length : 1995 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTCTTCACGTAAACATCTAGCAAATGCAATCCGCGCTTTAAGCATGGATGGTGTTCAACAAGCAAATTCTGGTCACCC
AGGCGCACCTATGGGTATGGCAGATATCGCTGAAGTATTATGGCGTAGCCACCTAAATCACAACCCACAAAATCCAGAGT
GGGCTGACCGCGACCGTTTTATTCTTTCAAATGGTCATGGCTCTATGCTGATTTATTCTCTGCTTCATCTTTCAGGTTAT
GACCTGTCTATCGAAGACTTAAAGAATTTCCGTCAACTGCATTCTAAAACTCCAGGTCACCCTGAGTATGGTTATGCACC
AGGCGTAGAAACAACTACGGGTCCATTAGGTCAAGGCATCACTAATGGTGTTGGTATGGCGATGGCTGAAAAAGCATTAG
CTGCACAATTTAACCGTGAAGGCCACGATATCGTTGATCACAACACATACGTGTTCATGGGTGACGGTTGTCTAATGGAA
GGTATCTCTCACGAAGCGTGTTCACTTGCTGGTACATTAGGTCTAGGCAAATTAATCGCATTTTGGGATGACAACGGTAT
CTCTATCGATGGTGAAGTTGAGGGTTGGTTCTCTGACGATACACCTAAACGCTTTGAAGCATACGGTTGGCATGTAATTC
CTGCGGTTGATGGCCACGATTCAGATGCTATCAATGCAGCAATTGAAGCGGCTAAAGCTGATCCTCGTCCTTCGTTAATT
TGTACTAAAACAGTAATTGGTTTTGGTTCTCCAAATAAACAAGGTACACATGACTGTCACGGTGCTCCATTAGGTGCTGA
AGAAATTGCAGCAACTAAAGCTCAATTGGGTTGGGAGCACGGTGCATTTGAAATTCCTGCAGATGTGTATGGCGAATGGG
ATGCAAAAGAAGCGGGTTCTGAAAAAGAAGCGGCTTGGAATGCAAAATTCGATGCATATGCTGCGGCATACCCTGAATTA
GCGGCAGAATATAAACGTCGTGTAAATGGTGACTTACCTGCAGAATGGGAAGAAAAAGCAAATGCAATTATTGCTGATCT
TCAAGCTAATCCTGCAAACATCGCATCACGTAAAGCATCTCAAAATGCACTAGAAGCGTTTGGTGCTATGCTACCTGAGT
TCATGGGCGGCTCTGCTGACCTTGCACCATCTAACCTAACGATGTGGTCAGGTTCTAAATCTTTAGAAGCAAATGACTTC
TCAGGTAACTACATCCACTACGGTGTGCGTGAATTCGGTATGACAGCAATCATGAATGGTATTGCTTTGCACGGTGGTTT
CGTACCATACGGTGCAACGTTCCTAATGTTCATGGAATACGCTCGTAACGCAATGCGCATGGCTGCACTAATGAAAGTGC
AAAACATCCAAGTTTACACACACGACTCTATCGGTCTTGGTGAAGATGGTCCAACTCACCAACCAGTTGAGCAAATTGCT
TCTCTACGTTTAACACCAAACATGAGCACATGGCGTCCATGTGACCAAGTTGAATCTGCTGTAGCATGGAAACTGGCTAT
CGAGCGTAAAGATGGTCCTTCTTCTTTAATCTTCTCTCGTCAAAACCTTGCACAACAAGAGCGTACACAAGAGCAAGTTG
CAGATATCGCTAAAGGTGCTTACATCCTTAAGGATTGTGAAGGCCAACCTGAGTTGATTCTTATTGCAACAGGTTCAGAA
GTTGAGCTTGCAGTTGAAGCAGCAGCACAACTGACAGCAGAAGGTAAAGCTGTACGTGTTGTTTCAATGCCATCAACAGA
TGCCTTTGATAAACAAGACGAAGCATACCGTGAAGCAGTACTTCCATCAGCGGTAACTAAACGTATCGCAATTGAAGCTG
GCATTGCTGATTTCTGGTACAAGTACGTTGGTTTCGGTGGCAAGATCATCGGTATGACAACATTTGGTGAGTCAGCACCT
GCTGATGAGCTATTCAAAATGTTTGGTTTCACTACTGAAAACGTAGTAAACACGGCGAAAGAACTTTTAGCTTAA

Protein sequence :
MSSRKHLANAIRALSMDGVQQANSGHPGAPMGMADIAEVLWRSHLNHNPQNPEWADRDRFILSNGHGSMLIYSLLHLSGY
DLSIEDLKNFRQLHSKTPGHPEYGYAPGVETTTGPLGQGITNGVGMAMAEKALAAQFNREGHDIVDHNTYVFMGDGCLME
GISHEACSLAGTLGLGKLIAFWDDNGISIDGEVEGWFSDDTPKRFEAYGWHVIPAVDGHDSDAINAAIEAAKADPRPSLI
CTKTVIGFGSPNKQGTHDCHGAPLGAEEIAATKAQLGWEHGAFEIPADVYGEWDAKEAGSEKEAAWNAKFDAYAAAYPEL
AAEYKRRVNGDLPAEWEEKANAIIADLQANPANIASRKASQNALEAFGAMLPEFMGGSADLAPSNLTMWSGSKSLEANDF
SGNYIHYGVREFGMTAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQPVEQIA
SLRLTPNMSTWRPCDQVESAVAWKLAIERKDGPSSLIFSRQNLAQQERTQEQVADIAKGAYILKDCEGQPELILIATGSE
VELAVEAAAQLTAEGKAVRVVSMPSTDAFDKQDEAYREAVLPSAVTKRIAIEAGIADFWYKYVGFGGKIIGMTTFGESAP
ADELFKMFGFTTENVVNTAKELLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 79
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 68