Gene Information

Name : metB (SeAg_B4347)
Accession : YP_002149029.1
Strain : Salmonella enterica SL483
Genome accession: NC_011149
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 4236102 - 4237262 bp
Length : 1161 bp
Strand : +
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGACGCGTAAACAGGCCACTATCGCAGTGCGTAGCGGATTAAACGACGACGAGCAATACGGCTGCGTTGTGCCGCCAAT
CCATCTCTCCAGCACCTATAACTTTACCGGTTTCAATGAGCCGCGCGCGCATGATTATTCCCGCCGCGGTAATCCCACGC
GTGATGTTGTTCAGCGCGCATTAGCGGAACTGGAAGGCGGCGCGGGCGCGGTATTGACGAATACCGGCATGTCGGCGATT
CATCTGGTCACCACCGTTTTCCTCAAGCCGGGCGATCTGCTGGTCGCGCCGCATGATTGCTATGGCGGCAGTTATCGTCT
GTTTGACAGTCTGGCGACACGCGGCTGTTATCGTGTGCGGTTTGTCGATCAGGGTGATGAACGCGCCTTACAGGCGGCGC
TGGAAGAAAAACCGAAGCTGGTACTGGTAGAAAGTCCAAGTAATCCATTGTTACGCGTGGTGGATATTGCGAAAATCTGT
CGGCTGGCGCGCGAGGCGGGCGCAGTGAGCGTCGTTGATAACACGTTTTTAAGCCCGGCGCTGCAAAATCCGCTGGCGTT
GGGTGCCGATCTGGTGTTGCATTCATGCACGAAATATCTCAATGGTCATTCGGATGTTGTGGCCGGCGTGGTGATTGCTA
AAGATCCGGAAATGGTCACTGAACTGGCGTGGTGGGCGAATAATATTGGCGTGACCGGCGGGGCGTTTGATAGCTATCTG
CTGCTGCGCGGTTTGCGAACTCTGGTGCCGCGTATGGAGCTGGCGCAGCGCAACGCGCAGGCGATTGTGAAATATCTGCA
AACCCAGCCGTTGGTGAAAAAACTGTATCACCCGTCGCTGCCGGAAAATCAGGGGCATGAAATTGCCGCGCGCCAGCAAA
AAGGCTTTGGCGCAATGTTGAGTTTTGAACTGGATGGGGATGAGGAGACGCTGCGTCGTTTTCTGGGCGGGCTGTCGCTG
TTTACGCTGGCGGAATCTTTAGGGGGAGTGGAAAGTTTGATCTCTCACGCCGCCACCATGACGCATGCCGGTATGTCGCC
GCAGGCGCGTGCCGCCGCCGGGATCTCCGAAACGCTACTGCGTATCTCCACCGGTATTGAAGATGGCGAAGATTTAATTG
CCGACCTGGAAAATGGCTTCCGGGCTGCAAACAAGGGGTAA

Protein sequence :
MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAI
HLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLATRGCYRVRFVDQGDERALQAALEEKPKLVLVESPSNPLLRVVDIAKIC
RLAREAGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPEMVTELAWWANNIGVTGGAFDSYL
LLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEETLRRFLGGLSL
FTLAESLGGVESLISHAATMTHAGMSPQARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-61 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-63 43
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 8e-51 41