Gene Information

Name : hemC (SeAg_B4166)
Accession : YP_002148864.1
Strain : Salmonella enterica SL483
Genome accession: NC_011149
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 4064795 - 4065757 bp
Length : 963 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
TTGATAATGACGGTAACAAGCATGTTAGACAATGTTTTAAGAATTGCCACACGCCAAAGTCCCCTTGCGCTTTGGCAGGC
ACATTATGTCAAAGACGCATTGATGGCAACCCATCCGGGACTGACGGTAGAACTGGTGCCGATGGTCACACGCGGCGACG
TGATCCTTGATACTCCCCTGGCGAAAGTGGGCGGTAAGGGACTGTTTGTTAAAGAGCTTGAAATCGCGCTGCTGGAAAAA
CGCGCTGATATCGCCGTGCACTCTATGAAAGACGTTCCGGTGGCCTTCCCGGACGGTCTCGGTCTGGTGACCATTTGCGA
GCGCGAAGATCCGCGCGACGCGTTTGTCTCGAATAAATATCACAGTCTGGACGATCTGCCCGCGGGTAGTATCGTCGGGA
CGTCCAGTTTGCGTCGCCAGTGTCAACTGGCGGAACGCCGTCCGGACCTCATTATCCGTTCGTTGCGCGGCAACGTCGGC
ACACGTCTCGGCAAGCTGGACAACGGCGACTATGACGCCATTATCCTGGCCGTGGCCGGTCTGAAACGCTTAGGTCTGGA
GTCGCGCATTCGCACAGCCTTGCCGCCCGACGTTTCGCTTCCTGCCGTAGGCCAGGGCGCCGTCGGGATTGAGTGTCGTC
TTGACGACGCGCGAACGCAGGCGCTGCTCGCACCGTTGAATCACTCGCAAACCGCGCTGCGCGTAACGGCGGAACGCGCT
ATGAACACCCGCCTGGAAGGCGGTTGTCAGGTGCCGATTGGCAGCTATGCAGAAATCATCAACGGTGAAATTTGGTTACG
CGCGCTGGTTGGCGCGCCGGACGGTTCGGTGATGGTGCGCGGCGAACGTCGTGGTTCTCCCGAGCAGGCGGAGCAAATGG
GCATCTCGCTTGCAGAGGAACTGCTGGAAAACGGCGCGCGCGCGATTCTGACGGAAGTTTATAACGGCGAGACGCCCGCA
TGA

Protein sequence :
MIMTVTSMLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKGLFVKELEIALLEK
RADIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVG
TRLGKLDNGDYDAIILAVAGLKRLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERA
MNTRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGARAILTEVYNGETPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-86 61
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-86 61