Gene Information

Name : topB (SeAg_B1877)
Accession : YP_002146741.1
Strain : Salmonella enterica SL483
Genome accession: NC_011149
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 1834674 - 1836623 bp
Length : 1950 bp
Strand : -
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCGGTTGTTTATTGCCGAAAAACCGAGTCTGGGGCGCGCCATTGCGGATGTGCTGCCAAAACCGCACCGTAAAGGCGA
TGGTTTTATTGAGTGCGGAAACGGGCAGGTCGTCACCTGGTGTATTGGTCATTTGCTGGAACAGGCGCAGCCGGATGCGT
ATGACAGCCGTTATGCGCGCTGGAATCTGGCTGACCTGCCTATCGTGCCGGAAAAATGGCAGCTTCAGCCTCGTCCTTCC
GTCACCAAACAGCTCAATGTGATTAAGCGCTTTTTGCATCAAGCCGGTGAAATTATTCACGCCGGCGACCCGGATCGCGA
AGGGCAGCTTCTGGTTGATGAAGTGCTGGATTATCTCCAGCTTCCTGCCGAAAAGCGCCAGCAGGTGCGGCGTTGTCTGA
TAAACGACCTTAACCCGCAGGCGGTCGAGCGTGCTATCGACAGGCTGCGAGCGAACAGCGACTTCGTGCCGCTGTGCGTC
TCCGCGCTGGCGCGAGCGCGAGCGGACTGGCTGTATGGCATTAATATGACCCGCGCTTACACGATCCTGGGCCGTAATGC
CGGCTATCAGGGCGTGTTATCCGTGGGACGCGTGCAGACGCCGGTACTGGGGCTGGTGGTGCGGCGAGACGAAGAGATTG
AGAACTTTGTCGCCAAAGACTTCTTTGAAGTGAAGGCGCACATCGTTACGCCTGCCGACGAGCGTTTTACCGCTATCTGG
CAGCCGAGCGAGGCGTGCGAACCTTATCAGGATGAAGAGGGGCGCTTGCTTCATCGTCCGCTGGCGGAGCATGTAGTGAA
CCGAATCAACGGTCAGCCCGCGCTGGTAACCAGTTATAATGATAAACGGGAATCAGAATCCGCGCCGCTGCCGTTTTCGC
TCTCGGCGCTACAGATTGAAGCCGCCAAACGCTTTGGCCTGAGCGCGCAAAACGTGCTTGATATTTGTCAGAAGCTCTAT
GAAACCCACAAACTGATTACCTATCCGCGTTCCGACTGCCGTTATCTGCCGGAAGAACACTTTGCCGGACGGCAGGCGGT
CATGAACGCGATTAGCGTCCACGCCCCGGATTTACTGCCGCAGTCTGTGGTTAATCCTGATACGCGCAATCGCTGCTGGG
ATGACAAAAAAGTGGATGCGCACCACGCGATTATCCCGACGGCGCGCAGTTCTTCTGTCCATCTGACGGAAAACGAAGCG
AAAGTGTACACCCTGATTGCGCGTCAGTATCTGATGCAGTTCTGCCCGGACGCGGTGTTTCGTAAATGCGTTATTGAACT
GGAAATCGCCAAAGGGAAATTTGTCGCCAAAGCGCGTTTTCTGGCGGAGGCCGGTTGGCGGACGTTACTGGGCAGTAAAG
AGCGCGACGAGGAAAACGACGGTACGCCGCTGCCAGTTGTCGCCAAAGGTGATGAGTTGCTGTGTGAAAAGGGGGAAGTG
GTCGAACGCCAAACCCAGCCGCCGCGTCATTTCACCGATGCGACATTGCTTTCCGCGATGACCGGAATTGCCCGCTTCGT
GCAGGATAAAGATCTGAAAAAGATCCTGCGCGCGACCGATGGGCTGGGGACGGAAGCCACGCGCGCCGGGATTATTGAGC
TGCTGTTCAAACGTAGCTTTCTGACCAAAAAAGGGCGCTACATTCATTCTACCGATGCTGGCAAAGCGTTAATACATTCG
CTGCCGGAAATGGCGGCCCGTCCAGATATGACCGCGCACTGGGAATCTGTTTTGACGCAAATCAGCGAAAAGCAGTGCCG
TTACCAGGATTTCATGCAACCGCTGGTCGACACGTTATATCAGCTGATCGAGCAGGCTAAGCGCACGCCGGTGAAGCGCT
TCAGAGGGATAGTCGCGCCAGGCGGCGGAGAAAAGAAAAAGAGCGCGCCGCGTAAGCGAGCGGGCAAAAAAAGCCCGCCT
GCTGAGGAGACAGGCCGTCAGACCGAATAA

Protein sequence :
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPS
VTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCV
SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIW
QPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLY
ETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQSVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEA
KVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEV
VERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHS
LPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVDTLYQLIEQAKRTPVKRFRGIVAPGGGEKKKSAPRKRAGKKSPP
AEETGRQTE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 6e-103 41
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 2e-110 41