Gene Information

Name : SSPA2548 (SSPA2548)
Accession : YP_002143393.1
Strain : Salmonella enterica AKU12601
Genome accession: NC_011147
Putative virulence/resistance : Virulence
Product : invasion protein regulator
Function : -
COG functional category : K : Transcription
COG ID : COG3710
EC number : -
Position : 2829938 - 2831599 bp
Length : 1662 bp
Strand : +
Note : Activates the expression of invasion genes and activates the expression of prgHIJK which is part of the pathogenicity island 1 type III secretion system

DNA sequence :
ATGCCACATTTTAATCCTGTTCCTGTATCGAATAAAAAATTCGTCTTTGATGATTTCATACTCAACATGGACGGCTCCCT
GCTACGCTCAGAAAAGAAAGTCAATATTCCGCCAAAAGAATATGCCGTTCTGGTCATCCTGCTCGAAGCCGCCGGCGAGA
TTGTGAGTAAAAACACCTTACTGGACCAGGTATGGGGCGACGCGGAAGTTAACGAAGAATCTCTTACCCGCTGTATTTAT
GCCTTACGACGTATTCTGTCGGAAGATAAAGAGCATCGTTACATTGAAACACTGTACGGACAGGGCTATCGGTTTAATCG
TCCGGTCGTAGTGGTGTCTCCGCCAGCGCCGCAACCTACGACTCATACATTGGCGATACTTCCTTTTCAGATGCAGGATC
AGGTTCAATCCGAGAGTCTGCATTACTCTATCGTGAAAGGATTATCGCAGTATGCACCCTTTGGCCTGAGCGTGCTGCCG
GTGACCATTACGAAGAACTGCCGCAGTGTTAAGGATATTCTTGAGCTCATGGATCAATTACGCCCCGATTATTATATCTC
CGGGCAGATGATACCCGATGGTAATGATAATATTGTACAGATCGAGATAGTTCGGGTTAAAGGTTATCACCTGCTGCACC
AGGAAAGCATTAAGTTGATAGAACACCAACCCGCTTCTCTCTTGCAAAACAAAATTGCGAATCTTTTGCTCAGATGTATT
CCCGGGCTTCGCTGGGACACAAAGCAGATTAGCGAGCTAAATTCGATTGACAGTACTATGGTTTACTTACGCGGTAAGCA
TGAGTTAAATCAATACACCCCCTATAGCTTACAGCAAGCGCTTAAATTGCTGACTCAATGCGTTAATATGTCGCCAAACA
GCATTGCGCCTTACTGTGCGCTGGCAGAATGCTACCTCAGCATGACGCAAATGGGGATTTTTGATAAACAAAACGCTATG
ATCAAAGCTAAAGAACATGCGATTAAGGCGACAGAGCTGGACCACAATAATCCACAAGCTTTAGGATTACTGGGGCTAAT
TAATACGATTCACTCAGAATACATCGTCGGGAGTTTGCTATTCAAACAAGCTAACTTACTTTCGCCCATTTCTGCAGATA
TTAAATATTATTATGGCTGGAATCTTTTCATGGCTGGTCAGTTGGAGGAGGCCTTACAAACGATTAACGAGTGTTTAAAA
TTGGACCCAACGCGCGCAGCCGCAGGGATCACTAAGCTGTGGATTACCTATTATCATACCGGTATTGATGATGCTATACG
TTTAGGCGATGAATTACGCTCACAACACCTGCAGGATAATCCAATATTATTAAGTATGCAGGTTATGTTTCTTTCGCTTA
AAGGTAAACATGAACTGGCACGAAAATTAACTAAAGAAATATCCACGCAGGAAATAACAGGACTTATTGCTGTTAATCTT
CTTTATGCTGAATACTGTCAGAATAGCGAGCGTGCCTTACCAACGATAAGAGAGTTTCTGGAAAGCGAACAGCGTATTGA
TAATAATCCGGGATTATTACCGTTAGTGCTGGTTGCCCACGGCGAAGCTATTGCCGAGAAAATGTGGAACAAATTTAAAA
ACGAAGACAATATTTGGTTCAAAAGATGGAAACAGGATCCCCGCTTGATTAAATTACGGTAA

Protein sequence :
MPHFNPVPVSNKKFVFDDFILNMDGSLLRSEKKVNIPPKEYAVLVILLEAAGEIVSKNTLLDQVWGDAEVNEESLTRCIY
ALRRILSEDKEHRYIETLYGQGYRFNRPVVVVSPPAPQPTTHTLAILPFQMQDQVQSESLHYSIVKGLSQYAPFGLSVLP
VTITKNCRSVKDILELMDQLRPDYYISGQMIPDGNDNIVQIEIVRVKGYHLLHQESIKLIEHQPASLLQNKIANLLLRCI
PGLRWDTKQISELNSIDSTMVYLRGKHELNQYTPYSLQQALKLLTQCVNMSPNSIAPYCALAECYLSMTQMGIFDKQNAM
IKAKEHAIKATELDHNNPQALGLLGLINTIHSEYIVGSLLFKQANLLSPISADIKYYYGWNLFMAGQLEEALQTINECLK
LDPTRAAAGITKLWITYYHTGIDDAIRLGDELRSQHLQDNPILLSMQVMFLSLKGKHELARKLTKEISTQEITGLIAVNL
LYAEYCQNSERALPTIREFLESEQRIDNNPGLLPLVLVAHGEAIAEKMWNKFKNEDNIWFKRWKQDPRLIKLR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iagA NP_457270.1 invasion protein regulator Not tested SPI-1 Protein 0.0 99
iagA NP_806479.1 invasion protein regulator Virulence SPI-1 Protein 0.0 99
hilA YP_217795.1 invasion protein regulator Virulence SPI-1 Protein 0.0 99
hilA NP_461797.1 invasion protein regulator Virulence SPI-1 Protein 0.0 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SSPA2548 YP_002143393.1 invasion protein regulator VFG0538 Protein 0.0 99