Gene Information

Name : AnaeK_3252 (AnaeK_3252)
Accession : YP_002135601.1
Strain : Anaeromyxobacter sp. K
Genome accession: NC_011145
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 3660870 - 3662150 bp
Length : 1281 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: ade:Adeh_3143 cystathionine gamma-synthase

DNA sequence :
ATGTCCGAAGACGTCCACCTCGACTCCAACGTGCCAGGCAACCCGGCCTACCACTTCACCATCGTCGCGCCCGGCACGCC
GGCACGGGCCGGCTGGGCGGAGCGTGCGCCGCTCGTCCCCGGGGCCGCGCTCGCCACGCAGTGCGTCCACGCGGGCGTGC
AGCCCGACCCCGCCTACGGCGCGGTCATGCCGCCCATCTACCAGTCGTCCACGTTCGCGTTCCGCGACGTGTGCACCAAC
GCCGGCTACGACTACACGCGCAGCGGCAACCCGACGCGCGCCGCGCTGGAGGAGGCCATCGCCACGCTGGAGGGCGGCGC
CGGGGCGACCTGCACCACCACCGGCATGGCCGCGGTGCTGGTGGCGCTCAACCTGCTCCCGCACGGCAGCCACCTGCTCT
GTACCGTGGACTGCTACGGCGGCACGTTCCGGACGCTCGAGCACGCGCGCCAGGCCTACGGGCTGGACGTCACCTACCTC
GATCTCGCCGACCTCGGCGCGGTCGAGCGCGCGCTGCGGCCGAACACCGGGATGGTCTGGATCGAGACGCCGTCGAATCC
GCTGCTCCGCCTCACCGACATCCGCGCGGTGGCCGAGCTGGCGCACCGGCGCGGCGCGCTCGTGGTGGTGGACAACACCT
TCCTCTCCCCGGCGCTCCAGCGCCCGTTCGAGCACGGCGCCGATCTGGTGGTGCACTCCACCACCAAGTACCTGAACGGC
CACAGCGACGTGGTCGGCGGTGCGGTGGTCGCGCCCCGCGGCCGCACCGCGCTCCTGCAGCGCATCCAGTCGATGAACAA
CCTGCTCGGCACCTCCCAGAGCCCGCACGACGCCTTCCTGGTGCTCCGCGGGCTGAAGACGCTGGCGCTCCGCGTGAAGG
CGCACGAGGCCGGCGCGCAGCGGGTGGCGGCGTTCCTGGCCGGCCACCCGCAGGTCGCGCGGGTCCACTACCCCGGCCTC
GCCTCGCACCCGCAGCACGCGCTCGCGCGCGCGCAGCAGCGCGGCTTCGGCGCCATGCTGAGCTTCGAGCTCCGCGACGG
CCGCCCGGATCGGGTGGACCACGTGCTGCGCACGCTGCGCTGGTTCACGCTGGCGGAGTCGCTGGGCGGCGTCGAGAGCC
TGGTGGCGCACCCGGCCTCGATGACGCACGCGTCGATGACGCCGGAGGCCCGGCAGCGGGCGGGCATCACCGACTCGGTG
ATCCGGCTCTCCATCGGGATCGAGGAGCCCACCGACCTGATCGACGACCTCGAGCGCGCGCTCGCGTCGCTGCCGGCCTG
A

Protein sequence :
MSEDVHLDSNVPGNPAYHFTIVAPGTPARAGWAERAPLVPGAALATQCVHAGVQPDPAYGAVMPPIYQSSTFAFRDVCTN
AGYDYTRSGNPTRAALEEAIATLEGGAGATCTTTGMAAVLVALNLLPHGSHLLCTVDCYGGTFRTLEHARQAYGLDVTYL
DLADLGAVERALRPNTGMVWIETPSNPLLRLTDIRAVAELAHRRGALVVVDNTFLSPALQRPFEHGADLVVHSTTKYLNG
HSDVVGGAVVAPRGRTALLQRIQSMNNLLGTSQSPHDAFLVLRGLKTLALRVKAHEAGAQRVAAFLAGHPQVARVHYPGL
ASHPQHALARAQQRGFGAMLSFELRDGRPDRVDHVLRTLRWFTLAESLGGVESLVAHPASMTHASMTPEARQRAGITDSV
IRLSIGIEEPTDLIDDLERALASLPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-65 42
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-64 42
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-54 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
AnaeK_3252 YP_002135601.1 cystathionine gamma-synthase BAC0207 Protein 9e-62 46