Gene Information

Name : guaA (AnaeK_1521)
Accession : YP_002133880.1
Strain : Anaeromyxobacter sp. K
Genome accession: NC_011145
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1725205 - 1726761 bp
Length : 1557 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGACATCCACTCAGAGAAGATCCTCATCCTCGACTTCGGGTCGCAGTACACGCAGCTCATCGCGCGGCGGCTGCGCGA
GCTGGGCGTCTACTGCGAGATCCACCCGTGCACCGCGAAGGCGGAGGCGATCCGCGCGTTCCGGCCCCGCGGCGTGGTGC
TCTCCGGCGGCCCGGCCTCGGTGCTCGCGGAGGGCAGCCCGCGCTGCGACCGGGTGGTGTTCGAGCTGGGCGTGCCGGTG
CTGGGCATCTGCTACGGCCTGCAGGTCCTCGCCGCCGAGCTGGGCGGCCGGGTGGACCAGGCGGCGCACCGCGAGTTCGG
GCCGGCCACCATCGAGGTGAAGGCGACCTCGCCGCTGTTCCAGGGCCTGCCCGCCACGCTCGACGTGTGGATGAGCCACG
GCGACCGGGTGGAGGCGCTGCCCCCCGGCTTCGAGCCCATCGCCGCCACCGCCTCGGCCCCGTACGCCGCGGTGGAGGAT
CGCGCCCGCCGCTTCTACGGCGTGCAGTTCCACCCCGAGGTGGTCCACACGCCGCGCGGCAAGGACGTGCTGCGCAACTT
CGCGTACGGCGTGTGCGGCTGCTCCGGCACCTGGTCCATGCGCGGCTACGCCGAGGCGGCGGTGGAGCAGATCCGCGCCC
AGGTGAAGGACGGCCACGTCATCTGCGCGCTGTCCGGCGGGGTGGACTCCGCGGTGGCCGCGCTGCTGGTGCACCGGGCC
ATCGGCGACCGGCTGCGCTGCATCTTCGTGGACAACGGCGTGCTCCGCGCCGGCGAGCGCCAGCAGGTCGAGGACGTGTT
CGGCGCCATGTTCCACCTGCCGCTCGTGACGGTGGACGCGTCGCGGCGCTTCCTCGGCGCGCTGGCGGGCGTGACCGACC
CCGAGCGGAAGCGCAAGATCATCGGGCACGAGTTCATCGCGGTGTTCGAGCAGGAGGTGGAGCGGCTCGCGGCGCACGGC
GCCCGCGCGAAGTTCCTGGTGCAGGGCACGCTCTACCCGGACGTCATCGAGTCGGTCTCGTTCCGGGGGCCGTCCGCCAC
CATCAAGAGCCACCACAACGTCGGCGGCCTGCCCGAGAAGATGAACCTCTCGCTGGTGGAGCCGCTCCGCGAGCTGTTCA
AGGACGAGGTGCGCCAGCTCGGCCTCGAGCTGGGCCTGCCCGAGGCGATCGTCCGGCGGCAGCCGTTCCCCGGCCCCGGG
CTCGCCATCCGCGTTCTCGGCGAGGTCACCGAGGAGCGGCTGGCGGTGCTGCGCCGCGCCGACACGATCGTGCAGGAGGA
GGTCCGCGCCGCCGGGCTGTACGAGAAGCTCTGGCAGGGGTTCGCGGTGCTCCTGCCGGTCCGCAGCGTCGGCGTCATGG
GCGACGAGCGCACCTACGAGTCCACCTGCGCGATCCGCGCGGTGGAGTCCACCGACGGCATGACCGGCGACTGGGCGCGG
CTCCCGTACGAGCTGCTGGCCCGGATGTCGTCGCGCATCATCAACGAGGTCCGCGGCATCAACCGCGTGGTCTACGACAT
CTCCTCCAAGCCGCCCGCCACCATCGAGTGGGAATGA

Protein sequence :
MDIHSEKILILDFGSQYTQLIARRLRELGVYCEIHPCTAKAEAIRAFRPRGVVLSGGPASVLAEGSPRCDRVVFELGVPV
LGICYGLQVLAAELGGRVDQAAHREFGPATIEVKATSPLFQGLPATLDVWMSHGDRVEALPPGFEPIAATASAPYAAVED
RARRFYGVQFHPEVVHTPRGKDVLRNFAYGVCGCSGTWSMRGYAEAAVEQIRAQVKDGHVICALSGGVDSAVAALLVHRA
IGDRLRCIFVDNGVLRAGERQQVEDVFGAMFHLPLVTVDASRRFLGALAGVTDPERKRKIIGHEFIAVFEQEVERLAAHG
ARAKFLVQGTLYPDVIESVSFRGPSATIKSHHNVGGLPEKMNLSLVEPLRELFKDEVRQLGLELGLPEAIVRRQPFPGPG
LAIRVLGEVTEERLAVLRRADTIVQEEVRAAGLYEKLWQGFAVLLPVRSVGVMGDERTYESTCAIRAVESTDGMTGDWAR
LPYELLARMSSRIINEVRGINRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-144 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-144 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-144 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-128 56