Gene Information

Name : thyA (PHZ_c0819)
Accession : YP_002129662.1
Strain : Phenylobacterium zucineum HLK1
Genome accession: NC_011144
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : -
Position : 903485 - 904345 bp
Length : 861 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAACGCCCACGTCGCCCTCGCCCAGCGCTACGCCGCCGCCCCGGACCATCCCGAGCGGCAGTACCTGAACCTGCTGGC
CGACATCCTGGAGACCGGCGCCGCCCGCGGCGACCGCACCGGCACCGGCACCCTGGGCGTCTTCGGCCGCCAGATGCGCT
TTGACCTCTCCCAGGGCTTCCCCCTGCTGACGACCAAGAAGCTGCACCGCAAGTCGATCATCCTGGAACTGCTGTGGTTC
CTGCGCGGCGACACCAACGTGCGCTGGCTGCAGGAGCGCGGGGTGTCCATCTGGGACGAATGGGCCGATGCCGACGGCGA
GCTCGGCCCCGTCTACGGCAAGCAATGGCGCTCTTGGGCGGCCCCGGACGGCCGCGTCATCGACCAGATCTCGGGCGTGG
TGAACAGCCTGAAGACCAATCCCGAGAGCCGCCGCCACATCGTTTCGGCCTGGAATCCGGCCGAGGTGGAGGACATGGCC
CTGCCGCCCTGCCATTGCCTGTTCCAGTTCTTCGTCGCCCCGGACAGGGACGGCGTGAAGCGGCTGTCGTGCCAGCTCTA
CCAGCGTTCGGCCGACGTGTTCCTGGGCGTGCCGTTCAACATCGCCAGCTACGCCCTGCTGACCCTGATGATGGCCAAGG
TGACGGGCTACGCGCCCGGCGAGTTCGTCCACACCCTGGGCGATGCGCACCTCTACCTGAACCACGTCGAGCAGGCCCGA
ATCCAGCTCGCCCGCGAGCCCATGCCGCTGCCGGTCATGCACGTGGCCGACAGGGACGACCTGTTCGCCTTCGCCTACGA
GGACTTCAAGCTCGAGGGCTACCAGGCGCACCCGTCGATCCCGGCCCCGATCGCGGTGTGA

Protein sequence :
MNAHVALAQRYAAAPDHPERQYLNLLADILETGAARGDRTGTGTLGVFGRQMRFDLSQGFPLLTTKKLHRKSIILELLWF
LRGDTNVRWLQERGVSIWDEWADADGELGPVYGKQWRSWAAPDGRVIDQISGVVNSLKTNPESRRHIVSAWNPAEVEDMA
LPPCHCLFQFFVAPDRDGVKRLSCQLYQRSADVFLGVPFNIASYALLTLMMAKVTGYAPGEFVHTLGDAHLYLNHVEQAR
IQLAREPMPLPVMHVADRDDLFAFAYEDFKLEGYQAHPSIPAPIAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 5e-73 60