Gene Information

Name : guaA (MADE_1005260)
Accession : YP_004426196.1
Strain : Alteromonas macleodii Deep ecotype
Genome accession: NC_011138
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2952111 - 2953688 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGACCACAAATATCCACGACCAACGCATACTCATTTTGGATTTTGGCTCGCAATACACGCAGTTAATTGCACGTCGCGT
TCGCGAAATTGGTGTTTACTGTGAGCTATGGGCTTGGGATGTCACGGAAGAGCAAATTCGCGAATTCAATCCGCAAGGTA
TCATTTTATCTGGTGGGCCTGAGTCGGTCACAGAAGAAGGCTCTCCGCGAGCGCCAGATTATGTATTTGAAGCTGGTGTG
CCTGTATTAGGCGTGTGCTACGGCATGCAAACAATGGCTCACCAATTAGGCGGTGGTGTATTAGGTTCTGATAAGCGCGA
GTTTGGCTACGCGCAGGTTGAAGTGATTAAACCAAGCCCGCTACTTGATAAAATTGAAGATGCCATTGGTGATAACGGCG
CAGCCCTGCTTGATGTATGGATGAGTCATGGGGACAAAGTGGCCGCTATTCCTGAAGGCTTTGAAACTATTGCGCAAACG
GCGTCATGCCCTCACGCTGCAATGTATAACGAAGAGAAGCAATTCTACGGTGTTCAATTCCACCCAGAAGTGACTCACAC
CCGCCAAGGTATGCGCTTACTTACCCAATTCGTAATGGATATTTGTAAGTGTGAAAAGCTGTGGACGGCAGGAGCGATAA
TAGAAGATGCCATTGAGCGCATTAAAGAAAAAGTAGGTGATGAGAGAGTTATTCTTGGTCTTTCAGGTGGCGTAGACTCT
TCAGTTACTGCCATGCTGCTTCACCGTGCTATAGGCAAAAACCTCACCTGTGTATTTGTAGATAACGGCCTGTTACGCCT
AAATGAAGCTGACCAGGTAATGGAAATGTTTGGCGACCACTTTGGGTTAAACATTATCCGTGTCGATGCAGAAGGGCGTT
TCTTAGACCGCCTTAAAGGCATTGAAGACCCAGAGCTTAAGCGTAAAGCCATCGGTAACGAGTTTGTTCGCGTATTCGAT
GAAGAGGCGAGTAAGTTAGAAAATGCCAAGTGGCTAGCACAGGGTACTATCTACCCAGACGTGATCGAGTCAGCGGGCTC
TGCAACAGGTAAAGCACACGTAATTAAGTCTCACCATAACGTAGGCGGCCTTCCAGAAGATATGGAACTAGGGCTAGTTG
AGCCACTGCGTGAGCTATTCAAAGACGAAGTACGTAAAATTGGCTTAGAACTAGGCTTGCCATACGACATGCTTTACCGT
CACCCGTTTCCTGGTCCGGGACTAGGCGTACGTGTGTTAGGCGAGATAAAGAAAGAGTATTGCGATTTACTTCGTCGTGC
CGATGCTATCTTTATCGAAGAATTGTATGCCGCCGATCTTTACCAGAAAGTAAGTCAAGCGTTCACGGTATTCTTACCCG
TGCGCTCAGTTGGCGTAATGGGTGATGCCCGCAAATACGACTGGGTAGTAAGTTTACGTGCGGTAGAAACCATCGACTTT
ATGACAGCGCATTGGGCACACCTTCCATATGATTTCTTAGGTAAAGTGTCGAACCGGATTATCAATGAAATCGACGGCAT
CAGCCGTGTGGTCTATGATATTTCAGGTAAACCGCCTGCTACCATTGAGTGGGAATAA

Protein sequence :
MTTNIHDQRILILDFGSQYTQLIARRVREIGVYCELWAWDVTEEQIREFNPQGIILSGGPESVTEEGSPRAPDYVFEAGV
PVLGVCYGMQTMAHQLGGGVLGSDKREFGYAQVEVIKPSPLLDKIEDAIGDNGAALLDVWMSHGDKVAAIPEGFETIAQT
ASCPHAAMYNEEKQFYGVQFHPEVTHTRQGMRLLTQFVMDICKCEKLWTAGAIIEDAIERIKEKVGDERVILGLSGGVDS
SVTAMLLHRAIGKNLTCVFVDNGLLRLNEADQVMEMFGDHFGLNIIRVDAEGRFLDRLKGIEDPELKRKAIGNEFVRVFD
EEASKLENAKWLAQGTIYPDVIESAGSATGKAHVIKSHHNVGGLPEDMELGLVEPLRELFKDEVRKIGLELGLPYDMLYR
HPFPGPGLGVRVLGEIKKEYCDLLRRADAIFIEELYAADLYQKVSQAFTVFLPVRSVGVMGDARKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGKVSNRIINEIDGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-130 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-130 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-130 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-114 48