Gene Information

Name : sirA (MADE_000001022075)
Accession : YP_008549847.1
Strain : Alteromonas macleodii Deep ecotype
Genome accession: NC_011138
Putative virulence/resistance : Virulence
Product : response regulator
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2363942 - 2364586 bp
Length : 645 bp
Strand : -
Note : in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate v

DNA sequence :
GTGATAAAAATAATCCTAGCAGACGACCACGACTTGGTCAGAACAGGGATACGCCGGATACTGGAAGATGTGGAAGACTT
CACGATTCTCGCAGAAGCGAAAAACGGTGAAGACGCGGTACAGAAGTGCCGTAAAAATGCCCCAGATGTGGTACTCATGG
ACGTGAATATGCCCGGGATAGGCGGGTTAGAGGCAACGAAAAGAATTGTTCGTATGTCTGAAAACACTCGGGTGATTTGT
GTTTCTATGCACAAAGAAAGCCCCATTCCTATGCAAGTGATGGACGCGGGCGCGTATGGGTTTCTCTCCAAAGACGCTGA
ACCCAAAGAGGTAATTCTTGCCATTCGTAAAGTAGCGGCAGGACAGAAATACCTTGATAGCGAAGTTGCCAATAGTATTG
CTATTGGCAAGTTATTGCCCAGTTCAGATAATCCATTTGACGATTTATCGAGTAGAGAACTTACCATAGCAATGCGATTA
ACCGAAGGGCACAAAGTGCCTGATATCGCTCGCGAGCTTAGTATTAACTCTAAAACGGTTAACACCTATCGTTATAGAAT
GTTTCAAAAGTTAGGCGTGAATTCTGACGTAGAGTTAACGCATTTAGCCTATCGTCATAAACTTATCAATCCTAACACCT
TTTAA

Protein sequence :
MIKIILADDHDLVRTGIRRILEDVEDFTILAEAKNGEDAVQKCRKNAPDVVLMDVNMPGIGGLEATKRIVRMSENTRVIC
VSMHKESPIPMQVMDAGAYGFLSKDAEPKEVILAIRKVAAGQKYLDSEVANSIAIGKLLPSSDNPFDDLSSRELTIAMRL
TEGHKVPDIARELSINSKTVNTYRYRMFQKLGVNSDVELTHLAYRHKLINPNTF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00302 YP_008207767.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Not tested AbaR25 Protein 5e-44 47
BJAB0868_00306 YP_008211632.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Not tested AbaR26 Protein 5e-44 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sirA YP_008549847.1 response regulator VFG1889 Protein 6e-48 49