Gene Information

Name : MADE_1009625 (MADE_1009625)
Accession : YP_004427061.1
Strain : Alteromonas macleodii Deep ecotype
Genome accession: NC_011138
Putative virulence/resistance : Resistance
Product : D-lactate dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1052
EC number : 1.1.1.28
Position : 2185708 - 2186733 bp
Length : 1026 bp
Strand : -
Note : fermentative; catalyzes the formationof pyruvate from lactate; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGAGCCAGAACAAAATTGAAACTGACAGTGAAAGTAGCAGAAAAGTTGTGTTTTTCAGCACCCGCCCGTATGAAAAAAA
CGTTTTCACTGCCTTACTTTGTGAACGCAATAAATCGCTGCCCCCCCGTATAGAAGCCACTTTCTTTGAACACCCTTTAA
ACCCTTCAACGGCGGCAAGTTGTAAAGGGTTTTCTGACGTCGTGGTATTTGTTAATGATAACGTAAATGCAGAAACAATT
GACGCACTTAAGCACGCCGACGTAGAGCACATTGCACTTCGCTGTGCAGGCTTTAACAACGTTGACGTTAATGCTGCTAC
CCGAGCAGGCATTTCGGTAAGCCGTGTACCTGCATACAGCCCTGAAACCGTTGCCGAGCATACCCTTGCCCTTATACTGA
CATTAAACCGTAAAACCCATAAAGCGTATAATCGCGTGAGAGAGGGTAATTTTAACCTTGCCGGGTTGATAGGGTTTACT
TTACATAATAAAACGGTAGGTGTAATCGGCACCGGCAGAATTGGCAAGGCCGTAATACGGATATTGTTAGGCTTTGGCTG
TCGCGTGCTTTGTTTTGACCCTATAGAAGACGTAAGCGTAAAGAAAATGGGAGCGCATTATGTCTCTCTTGACGAACTAT
TCGCAATGAGCGCGATAGTTACACTTCATTGCCCACTTAATGAACATAGTCATCACATCATCAACGAAAGTAGCCTTGCC
CAAATGCCCGACGGTGTCATGCTTATTAACACGTCCCGAGGGGGTTTAGTCGATAACGATGCGATAATAAAGGGCCTAAA
ATCAAGAAAAATTGGATATTTAGGGCTAGATGTATACGAACGTGAATCTGAACTCTTCTTTGTCGATCATTCCCAAGAAA
TCATTCAAGATGACGTATTTCAACGGTTAACCACTTTTCCTAATGTGTTGATAACAGGCCACCAGGGCTTCTTCACCGAA
GAAGCCCTAGAAGAAATTGCCAATACCACTATCGACAACATACTAAGCGGTAGCAATAGACTTTAA

Protein sequence :
MSQNKIETDSESSRKVVFFSTRPYEKNVFTALLCERNKSLPPRIEATFFEHPLNPSTAASCKGFSDVVVFVNDNVNAETI
DALKHADVEHIALRCAGFNNVDVNAATRAGISVSRVPAYSPETVAEHTLALILTLNRKTHKAYNRVREGNFNLAGLIGFT
LHNKTVGVIGTGRIGKAVIRILLGFGCRVLCFDPIEDVSVKKMGAHYVSLDELFAMSAIVTLHCPLNEHSHHIINESSLA
QMPDGVMLINTSRGGLVDNDAIIKGLKSRKIGYLGLDVYERESELFFVDHSQEIIQDDVFQRLTTFPNVLITGHQGFFTE
EALEEIANTTIDNILSGSNRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 2e-42 43
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 1e-42 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MADE_1009625 YP_004427061.1 D-lactate dehydrogenase AF130997.1.orf3.gene Protein 3e-40 44
MADE_1009625 YP_004427061.1 D-lactate dehydrogenase NC_005054.2598279.p0 Protein 2e-42 44
MADE_1009625 YP_004427061.1 D-lactate dehydrogenase NC_014475.1.orf2.gen Protein 2e-42 44
MADE_1009625 YP_004427061.1 D-lactate dehydrogenase U35369.1.gene5.p01 Protein 4e-43 43
MADE_1009625 YP_004427061.1 D-lactate dehydrogenase AF155139.2.orf4.gene Protein 2e-41 43
MADE_1009625 YP_004427061.1 D-lactate dehydrogenase AF310956.2.orf4.gene Protein 6e-43 42