Gene Information

Name : MADE_1000720 (MADE_1000720)
Accession : YP_004425291.1
Strain : Alteromonas macleodii Deep ecotype
Genome accession: NC_011138
Putative virulence/resistance : Unknown
Product : phosphomethylpyrimidine synthase ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 154528 - 156456 bp
Length : 1929 bp
Strand : -
Note : catalyzes the formation of 4-amino-2-methyl-5-phosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole and S-adenosyl-L-methionine in thiamine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Hom

DNA sequence :
ATGTCGAACAGACGCGAACAGCGCCAACAAGCGCAACAATTCATTAATGAACTAGCGGGCGAAGCCTACCCCAACTCAAC
ACGCCATTATGAAAGTGGAAGTAGAGACGATATCCGTGTGGCCATGCGCCTTATTCACCAGCACGACAGCTTGGTAGGCG
GCACAGAAGACAACCCTATCTTAGAACCCAACCCACCCATTCCGGTTTACGACACATCAGGCCCTTACGGCGACCCAAAG
GAAAATATTGACGTACACAAAGGTTTATCGCCTTTGCGTAAAACCTGGATTGAAGAGCGCAGCGATACCCGTGAGCTTGA
TGGCGTTTCATCAAGCTTTGCCAAAGAACGTGAAAACGACATTTTTACCGAAGACTTTCGCTTTATACGCAGTCGCAAAC
CGCTAAAAGCAAAAGCAGGCAAAAACGTTACACAGCTGCATTACGCCAGACAGGGCGTTATTACCCCTGAAATGGAATAC
ATTGCCATACGCGAAAACATGGGCCGCCAAGCCATTAAAGACGCCGAGCTAACTCAGCAGCACAAAGGCGAGCACTTTGG
CGCCAATTTACCCGAGACGATAACCCCTGAATTTGTGCGACAAGAAGTGGCCGCAGGGCGCGCTATTATTCCGTGTAACA
TTAATCACCCCGAACTCGAGCCAATGATTATTGGCCGTAACTTCTTAGTGAAAATTAACGCCAACATTGGTAATTCTGCA
GTAACGTCATCAATTGAAGAAGAGGTAGAAAAGCTGGTGTGGTCTACGCGCTGGGGCGCCGACACCATCATGGATTTATC
CACCGGCAGGAATATTCACGAAACCCGCGAGTGGCTGCTGCGAAATAGCCCAGTCCCCCTTGGTACCGTACCTATTTACC
AAGCGCTGGAAAAAGTGAATGGCGTAGCCGAAGACTTAACGTGGGAGATGTTTAAAGACACGCTTATCGAACAAGCCGAG
CAAGGGGTAGATTACTTCACTATTCACGCAGGCGTACTGCTTGAATATGTACACCTTACCGCAAAACGGGTAACCGGCAT
TGTATCTCGTGGCGGGTCGATTATGGCGAAGTGGTGTTTAAGTCATCACCAGCAAAGCTTTTTGTACGAGCACTTCAACG
ATATTTGCGAAATTTGCGCGAAATACGATGTAGCGCTGTCGCTAGGTGATGGCTTGCGCCCGGGCAGCGTAGCAGACGCT
AACGACGATGCGCAGTTTTCTGAACTACGTACCCTTGGTGAGCTAACTAAAATTGCCTGGGAATACGATGTTCAGGTAAT
GATTGAAGGCCCAGGGCATGTGCCAATGCACATGATTAAAGAGAACATGGAAGAGCAGCTTAAGCACTGTCATGAAGCAC
CGTTTTATACCCTGGGGCCACTAACCACAGATATTGCACCGGGCTACGATCATTTCACATCCGGCATTGGTGCCGCCATG
ATTGGCTGGTATGGCTGCGCCATGCTTTGCTATGTAACCCCTAAAGAGCACCTTGGTTTACCTAACAAGGAAGACGTTAA
ACAAGGCTTAATTACCTACAAAATTGCTGCTCACGCCGCTGATTTAGCTAAAGGCCACCCGGGCGCGCAAATTCGCGACA
ACGCCATGTCGAAAGCGCGCTTTGAGTTTAGATGGGAAGATCAGTTCAATTTAGCGTTAGACCCACATACCGCGCGTGCG
TATCACGATGAAACCCTTCCGCAAGCCTCTGGCAAAGTCGCACACTTTTGCTCTATGTGCGGGCCTAAATTCTGCAGCAT
GAAAATATCTCAGGAAGTACGGGATGTCGCTAAGCAGGCGGAAAACCTAGCTCCCGCCCAAGCCGCAGAAAAAGAAAAGG
AAAAAGGCATGAAGGACATGGCGAACGCATTTAATAAATCGGGCGCCGAGCTTTATCATACCGCCGACAGTAAGGTTGAA
TTGCCATGA

Protein sequence :
MSNRREQRQQAQQFINELAGEAYPNSTRHYESGSRDDIRVAMRLIHQHDSLVGGTEDNPILEPNPPIPVYDTSGPYGDPK
ENIDVHKGLSPLRKTWIEERSDTRELDGVSSSFAKERENDIFTEDFRFIRSRKPLKAKAGKNVTQLHYARQGVITPEMEY
IAIRENMGRQAIKDAELTQQHKGEHFGANLPETITPEFVRQEVAAGRAIIPCNINHPELEPMIIGRNFLVKINANIGNSA
VTSSIEEEVEKLVWSTRWGADTIMDLSTGRNIHETREWLLRNSPVPLGTVPIYQALEKVNGVAEDLTWEMFKDTLIEQAE
QGVDYFTIHAGVLLEYVHLTAKRVTGIVSRGGSIMAKWCLSHHQQSFLYEHFNDICEICAKYDVALSLGDGLRPGSVADA
NDDAQFSELRTLGELTKIAWEYDVQVMIEGPGHVPMHMIKENMEEQLKHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAM
IGWYGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPHTARA
YHDETLPQASGKVAHFCSMCGPKFCSMKISQEVRDVAKQAENLAPAQAAEKEKEKGMKDMANAFNKSGAELYHTADSKVE
LP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 72
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 72
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 68