Gene Information

Name : pyk (Sez_0882)
Accession : YP_002123253.1
Strain : Streptococcus equi MGCS10565
Genome accession: NC_011134
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 925545 - 927047 bp
Length : 1503 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGAATAAACGTGTAAAAATTGTTGCAACACTTGGTCCTGCGGTTGAAATTCGCGGTGGTAAAAAATATGGTGAGGACGG
CTATTGGGCTGGTCAGTTGGACGTTGAACAATCAGCTAAAAAAATCGCTGAATTGATTGAAGCAGGTGCTAACGTTTTCC
GCTTTAACTTTTCACATGGTGACCACAAAGAGCAGGGTGACCGTATGGCTACTGTTCGTCTTGCTGAAAAGCTGGCACGT
CAAAAGGTTGGTTTCCTTTTGGATACAAAAGGACCAGAAATGCGTACAGAATTGTTTGCTGATGATGCCAAAGAATATAG
CTATGTGACTGGTGAGCGTATTCGTGTTGCGACAGCACAAGGCATTCAATCAACTCGTGATGTGATTGCTTTGAATGTAG
CTGGTGCTCTTGATATTTATGATGAGGTTGAGGTTGGCCACACTATTCTTATTGACGATGGAAAGCTTGGCCTAAAGGTT
ATCGAAAAGGACATTGCAAAGCGTGAGTTTATCGTTGAGGTTGAAAATGATGGCATCATTGCAAAGCAAAAGGGTGTTAA
TATTCCTAATACTAAGATTCCTTTCCCAGCCTTAGCAGAACGTGACAATGCTGATATTCGTTTTGGTCTTGAGCAAGGTC
TTAACTTTATTGCTATTTCATTTGTTCGTACTGCCAAGGACGTTGAAGAGGTTCGTGAGATTTGTCGTGAAACAGGCAAT
GAGCATGTTCAATTATTTGCTAAAATCGAAAACCAACAAGGTATTGATAACCTTGATGAAATCATCGAAGCTGCAGATGG
TATCATGATTGCTCGTGGTGATATGGGGATTGAGGTGCCATTTGAAATGGTTCCAGTCTTCCAAAAAATGATTATCACCA
AGGTAAATGCAGCAGGTAAAGCAGTCATCACCGCAACTAACATGCTTGAAACAATGACTGAAAAACCACGTGCAACTCGT
TCAGAGGTATCTGACGTTTTCAACGCGGTTATTGACGGTACAGATGCGACAATGCTTTCTGGTGAGTCAGCAAATGGTAA
ATACCCTGTTGAGGCAGTTCGTACAATGGCTACAATTGATAAAAATGCACAAACTCTTCTTAATGAGTATGGTCGTTTAG
ACTCATCTGCCTTCCCACGTACCAATAAAACTGACGTGATTGCTTCAGCTGTTAAAGATGCAACACACTCAATGGATATC
AAGCTTGTTGTGACCATCACTGAAACAGGAAACACAGCTCGTGCCATTTCTAAGTTCCGTCCTGATGCTGACATCTTGGC
TGTGACCTTTGATGAAAAGGTTCAACGTGCCTTGATGATTAACTGGGGTGTGATTCCAGTGCTTGCTGAAAGACCAGCAT
CAACAGATGATATGTTTGAGGTAGCAGAGCGTGTAGCTCTTGAGACTGGTTTGGTGCAATCAGGAGATAATATCGTTATT
GTTGCAGGTGTGCCAGTTGGTACAGGTGGTACAAATACAATGCGTGTTCGCACTGTAAAATAA

Protein sequence :
MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEQSAKKIAELIEAGANVFRFNFSHGDHKEQGDRMATVRLAEKLAR
QKVGFLLDTKGPEMRTELFADDAKEYSYVTGERIRVATAQGIQSTRDVIALNVAGALDIYDEVEVGHTILIDDGKLGLKV
IEKDIAKREFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVEEVREICRETGN
EHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPVEAVRTMATIDKNAQTLLNEYGRLDSSAFPRTNKTDVIASAVKDATHSMDI
KLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAERPASTDDMFEVAERVALETGLVQSGDNIVI
VAGVPVGTGGTNTMRVRTVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 7e-81 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-80 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-80 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-80 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_002123253.1 pyruvate kinase VFG0479 Protein 5e-81 43