Gene Information

Name : polA (Sez_0182)
Accession : YP_002122573.1
Strain : Streptococcus equi MGCS10565
Genome accession: NC_011134
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : -
Position : 196567 - 199266 bp
Length : 2700 bp
Strand : +
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
TTGCAAAAAGCGAAGCTGGTCAGAGCAAAGCAGGTCACTGTGTGGTATAATAAAGGCATGGAAAACAAGAATAAATTACT
TTTGATTGATGGCTCCTCAGTGGCCTTTCGTGCCTTTTTTGCCCTCTATAACCAGATTGACCGCTTTAAAAATCACAGCG
GTCTTCACACTAATGCGATTTATGGCTTTCATTTGATGCTAGACCACATGATGAAGCGTGTTCAGCCGACGCATGTCCTA
GTGGCCTTTGACGCGGGTAAAACAACCTTTCGGACAGAGCTTTTTGCTGATTACAAGGCAGGACGTGCTAAGACGCCTGA
TGAATTTCGAGAGCAGTTTCCTTATATTCGTGATATGCTGGGAGCGCTTGGTATTGCCTTTTATGAGCTAGAGCATTACG
AGGCAGACGATATTATCGGAACGCTTGATAAAATGGCAGAGCGCACAGAGCTTCCTTTTGATGTGACTATTGTTAGCGGT
GACAAGGATTTGATTCAGCTGACAGATGCAAATACCGTTGTTGAGATTTCTAAAAAAGGAGTTGCTGAGTTTGAAGAGTT
TACCCCAGCCTACCTCATGGACAAAATGGGGCTTACGCCAGAGCAATTCATTGACTTGAAAGCGCTCATGGGAGACAAGT
CTGATAATATTCCAGGAGTGACCAAAATTGGGGAAAAAACAGGTTTAAAGCTCTTGCACGAATATGGCAGCCTAGAAGGC
ATCTACCAGCATGTGGATAGCTTTAAGCCATCAAAAATGAAGGAAAACTTGCTTCATGATAAGGAGCAGGCCTTCCTCTC
AAAGACACTTGCTACTATCAACACCAGTGCTCCGATTACGATTGGATTGGAGGATATTGTCTATCAGGGTCCAGATCTAG
ATCGCTTGTCACAATTTTATGATGAGATGGATTTTGTTCAACTAAAAAATGCCTTAGCTAGTCAGCTGCCACAGGAGCCG
GTAGCTGAGATTGCTTATCAGGAAGTCACTGACATAAGAGCGGACATGTTTTCAGATGATACAGTGTTTTATTTTGAGGC
TTTGAGGGATAATTATCACCGCGAGGAGCTGATTGGCTTTGCTTGGGGCAACCAAGGCCAGATTTATGCTTCAGCAGATA
TTAGCCTCCTCACAACAGAGCTCTTTAAAAAGGTTCTTGAGCAGCCGATTGCTACCTATGATTTTAAGCGCAGTAAGGTG
CTGCTTAGTCACCTAGGGCTTGATTTGCCGGCTGCCAGTTATGATGCCCGCTTAGCTAATTACCTCTTATCAACTGTAGA
GGACAATGAAATGGCTACTTTGGCACGTCTTTACACCACTATACCACTGGATACAGATGAGGTGGTTTATGGTAAGGGGG
TCAAGCGTGCTGTGCCTGACAAGGCTGTTTTGTTAGGACATCTGGCGCGTAAGGTTCAGGTCTTGCTGGATAGTAGACCA
GTCATGCTTGATAAGCTGGCAGAGCATGAGCAGGCTGATCTCTACACAGACATTGAATTGCCGCTTGCCAATGTTCTTGC
GAAAATGGAAATCGAAGGCATTGCTGTCAATCAAGATAGCCTGCAGGAAATGGCAGAGCAAAATAAGGTGGTCATTGAGG
AACTGACACAGGAAATCTATGAAATGGCTGGTGAGGTCTTTAATATTAATTCTCCCAAGCAGCTAGGAGTGATACTCTTT
GAGAAAATGCAGCTCCCTCTTCATTTGACAAAGAAAACCAAGACAGGCTATTCAACGGCTGTTGATGTCTTGGAGCGCTT
AGCGCCAATTGCGCCAATCGTGGCTAAGATCTTGGACTATCGTCAAATTACTAAGCTGCAATCAACCTATGTGATTGGAC
TGCAGGATTACATCATGGCTGATGGCAGGATCCACACCCGCTATTTACAGGATTTAACCCAGACAGGCCGACTTTCCAGT
GTTGATCCTAACCTGCAAAATATCCCGATTCGTCTGGAGCAGGGGCGCTTGATTCGTAAGGCCTTTACTCCATCTCATGA
TGATGCTGTTTTGCTTAGCTCGGATTATTCGCAAATTGAATTGCGTGTTTTAGCACATATTTCAGGAGATGAGCATTTGA
TTGCTGCTTTTAAGGAGGGAGCGGATATCCATACCTCAACGGCAATGCGTGTCTTTGGCATTGAAAAGCCAGAGGACGTC
ACTGCCAATGATCGTCGGAATGCTAAGGCTGTTAACTTTGGCATTGTGTATGGGATTTCTGACTTTGGCTTGTCTAATAA
CCTTGGAATTCCAAGAAAGCAGGCCAAGGCTTATATTGACACCTACTTTGAGCGCTACCCTGGTATCAAGGCTTACATGG
AAAGGGTTGTGCGTGAAGCCAAGGATAAGGGCTATGTTGAGACGCTCTTTAAGCGCCGTCGTCAATTGCCAGATATCAAT
TCTCGTCAATTTAACCTTCGTTCATTTGCGGAGCGTACAGCCATTAATTCACCAATTCAGGGCAGTGCAGCCGATATTCT
CAAAATTGCGATGATAAATCTTGACCAAGCCCTAGTAGCTGGTGGCTTTGAGACCAAAATGCTGCTTCAGGTGCATGATG
AGATTGTGCTTGAGGTGCCAAGCCATGAGCTAGCGGCTGTTAAAGAGCTGGTCAAAGAAACAATGGAATCAGCTGTCAAT
CTGGCAGTTCCGCTGCGTGTGGACGAAAGTGCTGGTAAGAGCTGGTATGAGGCCAAGTAG

Protein sequence :
MQKAKLVRAKQVTVWYNKGMENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHVL
VAFDAGKTTFRTELFADYKAGRAKTPDEFREQFPYIRDMLGALGIAFYELEHYEADDIIGTLDKMAERTELPFDVTIVSG
DKDLIQLTDANTVVEISKKGVAEFEEFTPAYLMDKMGLTPEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEYGSLEG
IYQHVDSFKPSKMKENLLHDKEQAFLSKTLATINTSAPITIGLEDIVYQGPDLDRLSQFYDEMDFVQLKNALASQLPQEP
VAEIAYQEVTDIRADMFSDDTVFYFEALRDNYHREELIGFAWGNQGQIYASADISLLTTELFKKVLEQPIATYDFKRSKV
LLSHLGLDLPAASYDARLANYLLSTVEDNEMATLARLYTTIPLDTDEVVYGKGVKRAVPDKAVLLGHLARKVQVLLDSRP
VMLDKLAEHEQADLYTDIELPLANVLAKMEIEGIAVNQDSLQEMAEQNKVVIEELTQEIYEMAGEVFNINSPKQLGVILF
EKMQLPLHLTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIMADGRIHTRYLQDLTQTGRLSS
VDPNLQNIPIRLEQGRLIRKAFTPSHDDAVLLSSDYSQIELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIEKPEDV
TANDRRNAKAVNFGIVYGISDFGLSNNLGIPRKQAKAYIDTYFERYPGIKAYMERVVREAKDKGYVETLFKRRRQLPDIN
SRQFNLRSFAERTAINSPIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIVLEVPSHELAAVKELVKETMESAVN
LAVPLRVDESAGKSWYEAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 86