Gene Information

Name : clpC (Sez_0140)
Accession : YP_002122531.1
Strain : Streptococcus equi MGCS10565
Genome accession: NC_011134
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 151392 - 153812 bp
Length : 2421 bp
Strand : +
Note : similar to ref|YP_603351.1| Negative regulator of genetic competence clpC/mecB [Streptococcus pyogenes MGAS10750]; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with dn

DNA sequence :
ATGCAAGACATTTTTAATCAGGCTCAATTTCAGGCAGAGCGCTTTGATAGTCCTTACCTTGAGACCTGGCACATTTTATT
AGCTATGGTAGCTGTTGATCATTCTTTAGCAGCCATGGTTTTAAGCGAATTTGAACGAAAGATCAGAGCTGAAGAGTATG
AGGCAGCTGCTATTTTAGCTATGGGAAAAAGTCCCAAGGAGGTGACTTCTGTCCAATTCAAGCCGCAATCCAAGGCCTTA
TCAGAAATACTAGCATTTGCTCATGCTATCTGTCAGGTCACCAATGAGCATGAGGTTGGCTCAGAGCATGTGCTTTTTGC
TATTTTGCTCAATCCGGACATTATGGCTAGTCGTCTATTAGAATTGGCAGGCTATAGGCTTAAGGATTCTGGCAAGGGAG
AGCCTAGGTTTGCGGATTTACGTAAGGCTATTGAGTTAAATGCCGGCTATAGTAAGGAAACCATTAAGGCGATTCATGAG
TTGCGTAAGCCTAAAAAGACGAAATCAGTAGGCACCTTTTCTGAAATGATGAAGCCACAGAGTACAGCTGGTGAGCTATC
AGACTTTACTAGAGACCTGACAGAGATGGCAAGACAGGGCTTGTTAGAGCCAGTTATCGGACGAGAAAAAGAGGTGTCAC
GTATGGTTCAGGTGCTCTGTCGTAAGACTAAAAATAATCCTGTTCTTGTTGGTGATGCGGGTGTTGGAAAAACTGCTCTA
GCTTATGGCTTGGCACAGCGTATTGCAAGCGGCGTGATTCCTTATGAATTACAGGACATGCGTGTCTTGGAGCTTGACAT
GATGAGTGTGGTTGCAGGTACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATCAACTCATTGACGATATTGAAGCAG
ATGGCAAAATCATCTTGTTTGTCGATGAGCTACATACCATTATGGGATCAGGAAGTGGTATTGACAGCACTCTTGATGCA
GCTAATATTCTAAAGCCAGCCCTTTCTCGCGGTACCCTGCATATGGTTGGCGCTACAACTCAAGAGGAATATCAAAAGCA
TATTGAAAAGGACGCAGCTCTTTCTCGTCGCTTTGCCAAGATATTGATTGAGGAGCCTAGTGTCGATGATGCTTATCAGA
TTTTGCTTGGCTTGAGGGCCTCCTATGAACAGTACCATAATGTAACAATCTCTGATAAAGCTGTTCATACTGCTGTGAAG
CTGGCCCAGCGCTACTTGACGAGTAAGCGGCTTCCAGATTCAGCGATTGATCTGCTTGATGAAGCTAGTGCGATGGTACA
AAGCATGGTTAAAAAGACGCAGCCTGACTTTATAACGCCGCTTGATCAAGCCCTGCTTGATGGTGATATGAGCAAGGTGT
CAGCCCTTTTAGCCAAAGAGGATAAGCAACCAAAGCTAAAACCAACAGCAGTTACTGAAGATGATATGTTACACACCTTA
AGCAAGCTATCAGGTATTCCCCTAGAAAAACTAACTCAGGCGGATAGTAAAAAATATCTGAATCTGGAAAAGGAATTGCA
TAAGCGTGTTGTTGGTCAGGAAATGGCTGTTTCTGCTATTGCACGAGCCATTCGTCGTAACCAGTCAGGCATTCGCACAG
GCAGGCGTCCGATTGGCTCCTTTATGTTTCTTGGTCCAACTGGTGTCGGAAAAACAGAGCTAGCAAAGGCCTTGGCCGAA
TTACTCTTTGATGATGAGTCAGCCCTTATTCGTTTTGATATGTCTGAGTACATGGAAAAATTTGCAGCCTCCCGTCTTAA
TGGGGCTCCTCCTGGCTATGTTGGCTATGATGAGGGAGGAGAGCTAACCGAAAAGGTTAGAAATAAGCCTTATGCCGTTC
TTCTTTTTGATGAGGTTGAAAAGGCTCACCCAGACATCTTTAATATCCTGCTGCAGGTCCTTGATGATGGTATGTTAACA
GATAGTCGTGGACGTAAGGTTGATTTTTCAAACACGATTATTATCATGACGAGCAACCTAGGAGCAACTGCTCTAAGAGA
TGATAAGACGGTTGGATTTGGCGCTAAAGCGATCGGTCATGACCATCAAGCAATGGAAAAGCGTATTTTAGAGGAATTGA
AAAAGGCTTATCGGCCTGAATTTATCAACAGAATTGATGAAAAGGTGGTCTTCCACAGCCTAACACAGGAAAACATGCGT
GATGTGGTCAAAATTATGGTTAAGCCGCTGATTGCAGCCTTGGCAGAAAAGCATATTAGCCTTAAGTTCCAGCCATCAGC
TCTCAAGTACTTGTCTGAAGCTGGTTACGATGTTGAAATGGGGGCTCGCCCACTTCGTCGCACCTTGCAAACAGAGGTTG
AGGACAGGTTAGCAGAATTAATGCTGTCAGGAGAGTTATCAAGCGGTCAAAGCCTCAAGATTGGTGTATCACATGGGAAG
TTAGCTTTTGATATTGCTTGA

Protein sequence :
MQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLAAMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQFKPQSKAL
SEILAFAHAICQVTNEHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKETIKAIHE
LRKPKKTKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKEVSRMVQVLCRKTKNNPVLVGDAGVGKTAL
AYGLAQRIASGVIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSGIDSTLDA
ANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVDDAYQILLGLRASYEQYHNVTISDKAVHTAVK
LAQRYLTSKRLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQALLDGDMSKVSALLAKEDKQPKLKPTAVTEDDMLHTL
SKLSGIPLEKLTQADSKKYLNLEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTELAKALAE
LLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFDEVEKAHPDIFNILLQVLDDGMLT
DSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKAIGHDHQAMEKRILEELKKAYRPEFINRIDEKVVFHSLTQENMR
DVVKIMVKPLIAALAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQSLKIGVSHGK
LAFDIA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-147 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_002122531.1 ATP-dependent Clp protease ATP-binding subunit VFG0079 Protein 8e-170 46
clpC YP_002122531.1 ATP-dependent Clp protease ATP-binding subunit VFG0080 Protein 1e-126 44