Gene Information

Name : phoP (Sez_1369)
Accession : YP_002123718.1
Strain : Streptococcus equi MGCS10565
Genome accession: NC_011134
Putative virulence/resistance : Resistance
Product : alkaline phosphatase synthesis transcriptional regulatory protein PhoP
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 1408225 - 1408968 bp
Length : 744 bp
Strand : -
Note : similar to ref|ZP_01817666.1| response regulator [Streptococcus pneumoniae SP3-BS71]; Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase.

DNA sequence :
GTGACTGATAGGAGTTATGAAATGACAAAACGAGTATTATTAGTAGATGATGAGGAGCCTATCTTAAGGCTACTGGATTA
TCACTTGGCCAAGGAGGGCTTTGTGACAGAGATGGTAACAGATGGCCGTACTGCCTTGGCATTAGCTGAAAGAGAACCTT
ATGATTTTATTGTGTTAGATATTATGCTGCCGCAATTAGACGGTATCGAGGTCTGCAAAAGGCTTCGTTCTAAGGGAAGT
AAAACCCCAATTATGATGGTTTCTGCTAAAAGTGATGAATTTGACAAGGTTTTGGCTTTGGAACTGGGGGCAGATGATTA
TGTGACCAAGCCCTTTAGTCCTAGAGAATTATTAGCGCGTGTCAAGGCTATTTTAAGGCGCACTGAAGCAGAGATTTCTG
GTGATGGTGAGGAGCATCGTGAGCCTTTTTATACGATGAGTCAATTGCGTCTGTACCCAGAGCGACATGAGGTCTATAAG
GACAAGGAGCTATTGCCGTTAACCCCAAAGGAATATGAGCTACTGCTCTATCTCATGAAGCACCCTAATATGACCTTGAC
GCGTGAGCGGCTATTAGAGCGTATCTGGGGTTATGACTTTGGCCAAGAAACACGTCTGGTAGACGTTCATATTGGCAAGC
TCAGAGAAAAAATTGAGGACAATCCTAAGGCGCCTCAGTATATTCAAACCATTCGCGGCTATGGATACAAATTTAAGGAG
CTAAAGAATGATAGGACATCTTAG

Protein sequence :
MTDRSYEMTKRVLLVDDEEPILRLLDYHLAKEGFVTEMVTDGRTALALAEREPYDFIVLDIMLPQLDGIEVCKRLRSKGS
KTPIMMVSAKSDEFDKVLALELGADDYVTKPFSPRELLARVKAILRRTEAEISGDGEEHREPFYTMSQLRLYPERHEVYK
DKELLPLTPKEYELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAPQYIQTIRGYGYKFKE
LKNDRTS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanRB YP_008394254.1 DNA-binding response regulator VanRB Not tested Not named Protein 2e-31 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
phoP YP_002123718.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_012469.1.7686381. Protein 4e-92 82
phoP YP_002123718.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_002952.2859905.p0 Protein 1e-58 53
phoP YP_002123718.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_002758.1121668.p0 Protein 1e-58 52
phoP YP_002123718.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_009641.5332272.p0 Protein 1e-58 52
phoP YP_002123718.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_013450.8614421.p0 Protein 1e-58 52
phoP YP_002123718.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_007793.3914279.p0 Protein 1e-58 52
phoP YP_002123718.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_003923.1003749.p0 Protein 1e-58 52
phoP YP_002123718.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_002745.1124361.p0 Protein 1e-58 52
phoP YP_002123718.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_009782.5559369.p0 Protein 1e-58 52
phoP YP_002123718.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_002951.3237708.p0 Protein 1e-58 52
phoP YP_002123718.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_007622.3794472.p0 Protein 1e-58 52
phoP YP_002123718.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP HE999704.1.gene2815. Protein 3e-60 52
phoP YP_002123718.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_012469.1.7685629. Protein 1e-47 50
phoP YP_002123718.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP AE016830.1.gene1681. Protein 1e-57 49
phoP YP_002123718.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP CP001485.1.gene721.p Protein 8e-38 42
phoP YP_002123718.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP AF310956.2.orf0.gene Protein 8e-32 41
phoP YP_002123718.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP HE999704.1.gene1528. Protein 5e-38 41