Gene Information

Name : lysS (Sez_1346)
Accession : YP_002123695.1
Strain : Streptococcus equi MGCS10565
Genome accession: NC_011134
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 1388200 - 1389705 bp
Length : 1506 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
TTGGAGGAAAACATGTCAAATCAACACATCGAAGAATTAAATGATCAACAAATTGTCCGTCGTGAAAAAATGGCAGCCTT
AGCTGAGCAAGGCATTGATCCATTTGGCAAACGCTTCGACCGAACAACTAATTCTGGTGAATTAAAGGAAAAATACTCAG
ACAAAACCAAAGAGGATTTACAAGAGCTTCAAGCCACTGCGATTATTGCTGGTCGTCTGATGACCAAGCGTGGTAAAGGA
AAGGTGGGCTTTGCTCATCTTCAGGATCGTCAAGGGCAAATCCAGATCTACGTTCGCAAGGATTCAGTTGGTGATGAAAA
CTATGACATTTTCAAGAAAGCTGACCTTGGTGATTTTATCGGGGTCGAAGGCGACATTATGCGTACTGATATGGGTGAGC
TGTCTATCAAGGCGACAAAACTAACCCACCTCTCCAAATCTCTACGTCCGCTACCAGAGAAATTTCATGGCTTAACTGAT
ATCGAAACCATTTATCGCAAACGTCATCTGGATTTGATTTCAAACCGCAGCAGCTTTGAGCGGTTCGTCACACGTTCAAA
AATGATTTCTGAAATTCGTCGTTATCTTGATGGCCTTGGCTTTTTAGAAGTGGAGACACCTGTCCTTCATAATGAAGCTG
GTGGTGCTGCTGCTCGTCCCTTTATCACTCACCACAATGCCCAAGATATTGACATGGTGCTTCGTATTGCAACAGAGCTG
CACCTCAAACGTCTCATCGTCGGTGGCATGGAACGTGTCTATGAAATTGGACGTATCTTCCGCAATGAGGGAATGGATGC
CACACACAACCCTGAATTCACTTCTATTGAGGTTTATGAAGCCTATGCAGACTATCTAGATATGATGAATCTAACCGAGG
GTATCATTCAGCATGCTGCTAAAGCCGTTAGGGGAGAGGGACCAGTTGATTATCAAGGAACTGAGATTAAGATCAATGAG
CCCTTTAAGCGTATCCATATGGTTGATGCCATCAAGGAGGTAACTGGTATTGACTTCTGGCCTGAGATGACTTTTGAGGA
AGCAACAGCTCTTGCTAACGAAAAGCATGTGCCACTTGAAAAGCACTTTACCTCTGTTGGTCATATCATTAATGCCTTCT
TTGAAGCCTTTGTCGAAGACACTCTCATTCAACCAACCTTTGTTTACGGACACCCCGTAGAGGTCTCACCACTCGCTAAG
AAAAATCCTGAGGACAGCCGCTTCACAGACCGCTTTGAGCTCTTTATCATGACCAAGGAGTACGCTAATGCCTTTACCGA
GCTAAATGATCCAATTGATCAGCTGTCACGCTTTAAGGCACAGGCAGCAGCCAAGGAGCTTGGAGACGATGAAGCAACCG
GTATTGACTACGACTTCGTTGAAGCCCTTGAGTACGGTATGCCACCAACAGGCGGGCTTGGAATCGGTATTGACCGTCTT
TGTATGCTGCTAACCAATACAACAACAATTCGCGATGTGCTCTTGTTCCCAACAATGAAGCCATAA

Protein sequence :
MEENMSNQHIEELNDQQIVRREKMAALAEQGIDPFGKRFDRTTNSGELKEKYSDKTKEDLQELQATAIIAGRLMTKRGKG
KVGFAHLQDRQGQIQIYVRKDSVGDENYDIFKKADLGDFIGVEGDIMRTDMGELSIKATKLTHLSKSLRPLPEKFHGLTD
IETIYRKRHLDLISNRSSFERFVTRSKMISEIRRYLDGLGFLEVETPVLHNEAGGAAARPFITHHNAQDIDMVLRIATEL
HLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYEAYADYLDMMNLTEGIIQHAAKAVRGEGPVDYQGTEIKINE
PFKRIHMVDAIKEVTGIDFWPEMTFEEATALANEKHVPLEKHFTSVGHIINAFFEAFVEDTLIQPTFVYGHPVEVSPLAK
KNPEDSRFTDRFELFIMTKEYANAFTELNDPIDQLSRFKAQAAAKELGDDEATGIDYDFVEALEYGMPPTGGLGIGIDRL
CMLLTNTTTIRDVLLFPTMKP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 3e-105 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_002123695.1 lysyl-tRNA synthetase VFG1668 Protein 2e-105 47