Gene Information

Name : clpL (Sez_1072)
Accession : YP_002123437.1
Strain : Streptococcus equi MGCS10565
Genome accession: NC_011134
Putative virulence/resistance : Virulence
Product : ATP-dependent protease ATP-binding subunit ClpL
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1104821 - 1106914 bp
Length : 2094 bp
Strand : +
Note : similar to ref|YP_598361.1| ATP-dependent endopeptidase clp ATP-binding subunit clpL [Streptococcus pyogenes MGAS10270]; Could be the ATP-dependent specificity component of an ATP-dependent protease.

DNA sequence :
ATGACAACTTATTATGGAAAAGACCCCTTTGGAAATATGGACGATATTTTCAATCAATTAATGGGAAACATTGGTGGCTA
TCGCAGTGAAAATCGGCGCTATCTTGTCAATGGACGTGAGATGACACCAGAGGAATTTCAGGAATACCGGAAAACCGGTA
AGCTAGCTGCAACTGAAGGACAAGACAAACAGGCTGGTAGCCTTAAAAAAGACGGCATTCTAACCAAGCTCGGAACAAAT
CTGACTGAAGAAGCTCGTCAAGGAAGGCTAGATCCTGTCATCGGACGAAACGATGAGATTCAAGCAACCGCAGAAATTCT
AGCTAGGCGAACCAAGAATAACCCTGTGCTTGTCGGTGACGCTGGCGTTGGTAAAACTGCTGTTGTCGAAGGTTTAGCCC
AGGCTATCGTCAATGGTGATGTGCCAGCTGCTATCAAAAATAAAGAGATTATCTCAATTGATATTTCTGGCCTTGAGGCT
GGCACACAGTATCGTGGCTCCTTTGAAGAAAACATTCAAAACATGGTTAAAGAGGTTAAAGAGGCTGGTAATATTATCCT
CTTCTTTGACGAAATTCATCAAATCCTTGGTGCAGGGTCAGCTGGTTCAGACTCAGGCTCTAAAGGCTTGGCTGATATTC
TAAAGCCAGCCCTCTCACGCGGTGAGTTGACCTTGATTGGTGCCACAACTCAAGATGAGTATCGCAATACTATTTTAAAA
AATGCTGCCCTTGCTCGTCGTTTCAACGAGGTTAAGGTTAATGCTCCTTCAGCAGAGGATACCTTCCACATATTGATGGG
CATTCGCAACCTCTACGAGCAGCACCACAATGTGATCCTGCCAGATTCTGTCTTGAAAGCAGCTATTGATTATGCTATCC
AATATATTCCACAACGAAGCCTGCCTGATAAAGCCATTGACCTTGTTGATATGACGGCTGCCCACCTAGCAGCTCAGCAC
CCTGTCACTGATCTAAAGTCACTTGAAGCAGAAATCGCTAAGCAAAAGGAGCTACAGGAAAAGGCTGTTGCAGAAGAAGA
CTTTGAAAAGGCCTTAACTGCTAAGACACGCATTGAGGAGCTTCAAAAGCAAATCAATCATCACAGTGAAGGGCAAAAGG
TCACTGCCACCGTCAATGATATTGCAGAATCTGTTGAACGACTAACTGGTGTCCCAGTCTCAAATATGGGGGCTAATGAT
TTAGAAAGGCTCAAAGAAATCAGTAATCGTCTTAAAGGCCATGTTATCGGACAAGATGGTGCAGTTGAGGCTGTTGCTCG
TGCGATTCGACGCAACCGCGCAGGCTTTGATGACGGTAATCGCCCAATTGGCTCCTTCCTCTTTGTTGGCCCAACTGGTG
TTGGTAAGACCGAGCTGGCTAAGCAGTTAGCCCTTGATATGTTCGGCTCAAAGGACGCTATCATTCGCTTAGATATGTCT
GAATATAGTGACCGCACAGCTGTTTCCAAATTAATCGGAACAACAGCTGGCTATGTTGGCTATGATGATAATCAAAATAC
CCTTACAGAACGTGTCCGTCGCAGTCCTTACTCTATCATCTTGCTTGATGAAATCGAAAAAGCAGACCCACAGGTCATTA
CACTGCTTCTTCAAGTGCTTGATGATGGGCGATTGACAGATGGACAAGGCAACACGATCAATTTCAAAAATACGGTTATC
ATCGCAACCTCTAATGCTGGTTTTGGCCATCAAGCAGGAGATAGTGCTGATCAAGAGCCTGCTATCATGGAGCGTATTGC
ACCTTACTTTAGACCAGAATTCTTGAATCGCTTCAACGGTGTCATCGAATTCAACCATTTAGCGAAAAAGGATCTACAAG
AAATCGTTGCTTTAATGCTAGCAGAGGTGAACCAAACCCTTGCTAAAAAAGGGATTAGCCTTGAGGTGACTGACGATGTT
AAAGAGCGTTTGATTGATCTGGGCTATGATCATGCAATGGGAGTTCGTCCACTTAGACGTGTCATCGAACAAGAAATTCG
TGACCGCATTACGGATTACTACCTGGATCACCCGACTGCTAAACACCTATTAGCAAGCCTTGATCAAGATACTATTACGA
TAAGTGAGAAGTAA

Protein sequence :
MTTYYGKDPFGNMDDIFNQLMGNIGGYRSENRRYLVNGREMTPEEFQEYRKTGKLAATEGQDKQAGSLKKDGILTKLGTN
LTEEARQGRLDPVIGRNDEIQATAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGSFEENIQNMVKEVKEAGNIILFFDEIHQILGAGSAGSDSGSKGLADILKPALSRGELTLIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHNVILPDSVLKAAIDYAIQYIPQRSLPDKAIDLVDMTAAHLAAQH
PVTDLKSLEAEIAKQKELQEKAVAEEDFEKALTAKTRIEELQKQINHHSEGQKVTATVNDIAESVERLTGVPVSNMGAND
LERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDMFGSKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNQNTLTERVRRSPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNTVI
IATSNAGFGHQAGDSADQEPAIMERIAPYFRPEFLNRFNGVIEFNHLAKKDLQEIVALMLAEVNQTLAKKGISLEVTDDV
KERLIDLGYDHAMGVRPLRRVIEQEIRDRITDYYLDHPTAKHLLASLDQDTITISEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 4e-128 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpL YP_002123437.1 ATP-dependent protease ATP-binding subunit ClpL VFG0080 Protein 2e-150 48
clpL YP_002123437.1 ATP-dependent protease ATP-binding subunit ClpL VFG0079 Protein 2e-132 44