Gene Information

Name : guaA (Sez_1010)
Accession : YP_002123377.1
Strain : Streptococcus equi MGCS10565
Genome accession: NC_011134
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1047063 - 1048610 bp
Length : 1548 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGTTGAATGATGTTCAAAAAATTATCGTTCTTGATTACGGTAGTCAGTACAATCAACTGATTGCAAGACGTATTCGGGA
GTTTGGTGTTTTTTCTGAGCTCAAAAGCCATCACATCACTGCGCAAGAGCTTCGTGACATCAATCCAATCGGGATTGTCC
TGTCTGGTGGGCCAAATTCTGTTTATGCAACTGATGCCTTTGGTATTGATCCTGAAATCTTTGAATTAGGGATTCCAATT
TTAGGGATTTGCTATGGCATGCAGCTAATCACACATACCTTAGGAGGTAAGGTAGTCCCAGCTGGTCAAGCAGGTCACCG
AGAATATGGTCAATCATCATTACGTTTACGTTCTGCATCAGCATTATTTGCGGGCACTCCAGATGAGCAGCTTGTTTTGA
TGAGTCATGGTGATGCTGTTACAGAAATTCCAGAGGGCTTTCATCTTGTAGGAGATTCTAACGATTGCCCTTACGCTGCT
ATGGAAAATACAAAAAAGAGGCTCTACGGTATCCAATTCCACCCAGAGGTAAGACACTCTGTCTATGGTAATGATATTTT
GAAGAACTTTGCTATCTCTATCTGTGGTGGACGTGGTGATTGGTCAATGGATAATTTTATTGACATGCAAATTGCTAAAA
TTCGCGAAACAGTCGGAGATCGTAAGGTTTTGCTAGGTTTGTCTGGTGGTGTTGATTCTTCAGTTGTTGGTGTCCTTTTA
CAAAAAGCCATCGGAGATCAATTAACCTGTATCTTTGTTGACCATGGACTTCTTCGTAAAAATGAAGGTGACCAAGTTAT
GGAAATGCTTGGTGGAAGATTTGGTCTCAATATTATTCGTGTTGATGCCTCAAAGCGCTTTTTAGATCTTCTTGCAGGCG
TTGAGGATCCTGAGAAAAAACGTAAAATTATCGGTAATGAGTTTGTTTACGTCTTTGATGACGAGGCTAGCAAGCTTAAG
GGCGTTGACTTCCTTGCACAAGGAACGCTTTACACAGACATCATTGAATCTGGAACAGAAACTGCTCAAACGATAAAATC
TCACCACAATGTTGGTGGTCTGCCAGAGGATATGCAGTTTGAATTAATCGAACCCCTCAATACACTCTTTAAAGATGAGG
TTCGTGCTCTTGGTACGGCCCTTGGTATGCCAGATGAAGTCGTCTGGCGTCAGCCTTTCCCAGGCCCAGGCCTTGCCATT
CGCGTCATGGGAGAGATCACAGCAGAAAAGCTTGAAACAGTTCGCGAGTCAGATGCTATCCTTCGAGAAGAAATTGCTAA
AGCAGGACTTGAGCGTGATGTGTGGCAATATTTTACAGTTAACACAGGTGTTCGTTCTGTCGGAGTTATGGGAGATGGTC
GTACCTATGACTATACCATCGCTATTCGTGCTATCACCTCAATTGATGGTATGACAGCAGACTTTGCCCAATTGCCTTGG
GAAGTTCTAAAGAAAATCTCAGTTCGAATTGTCAATGAAGTCGACCACGTTAATCGAATTGTCTACGACATCACCAGCAA
ACCACCAGCAACCGTTGAGTGGGAGTGA

Protein sequence :
MLNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHHITAQELRDINPIGIVLSGGPNSVYATDAFGIDPEIFELGIPI
LGICYGMQLITHTLGGKVVPAGQAGHREYGQSSLRLRSASALFAGTPDEQLVLMSHGDAVTEIPEGFHLVGDSNDCPYAA
MENTKKRLYGIQFHPEVRHSVYGNDILKNFAISICGGRGDWSMDNFIDMQIAKIRETVGDRKVLLGLSGGVDSSVVGVLL
QKAIGDQLTCIFVDHGLLRKNEGDQVMEMLGGRFGLNIIRVDASKRFLDLLAGVEDPEKKRKIIGNEFVYVFDDEASKLK
GVDFLAQGTLYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEVVWRQPFPGPGLAI
RVMGEITAEKLETVRESDAILREEIAKAGLERDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPW
EVLKKISVRIVNEVDHVNRIVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-172 70
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-172 70
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-173 70
guaA NP_938969.1 GMP synthase Not tested Not named Protein 8e-117 50