Gene Information

Name : alr (SeSA_A4495)
Accession : YP_002117180.1
Strain : Salmonella enterica CVM19633
Genome accession: NC_011094
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 4358593 - 4359672 bp
Length : 1080 bp
Strand : +
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
ATGCAAGCGGCAACAGTCGTCATTAACCGCCGCGCTCTGCGACACAACCTGCAACGTCTGCGTGAACTGGCGCCTGCCAG
TAAGCTGGTTGCGGTGGTGAAAGCGAACGCTTATGGACACGGTCTTCTGGAGACCGCGCGAACGCTCCCTGATGCTGACG
CTTTTGGCGTGGCGCGTCTTGAAGAGGCTCTACGTCTGCGAGCGGGCGGGATCACGCAGCCTATCCTGCTGCTGGAGGGT
TTTTTCGACGCCGCCGATCTGCCGACCATTTCCGCGCAATGTCTGCATACCGCCGTACATAATCAGGAGCAGCTTGCCGC
CCTGGAGGCGGTGGAGCTGGCGGAGCCAGTAACGGTCTGGATGAAACTGGATACCGGTATGCATCGTCTCGGCGTGCGTC
CCGAAGAGGCGGAGGCGTTCTACCAGCGTCTGACGCACTGTAAAAATGTACGCCAGCCGGTGAATATCGTCAGCCATTTT
GCCCGTGCGGATGAGCCGGAATGCGGCGCTACCGAACATCAGCTCGACATTTTTAATGCCTTCTGTCAGGGTAAACCCGG
TCAGCGCTCTATTGCCGCGTCTGGCGGTATTCTGCTGTGGCCGCAGTCTCACTTTGACTGGGCGCGTCCGGGCATCATTT
TGTATGGCGTATCGCCGCTGGAACACAAACCCTGGGGGCCGGATTTTGGTTTTCAGCCGGTGATGTCTTTAACCTCCAGT
TTGATCGCGGTGCGTGACCACAAAGCGGGCGAACCGGTGGGCTACGGCGGGACATGGGTGAGTGAGCGCGACACGCGCCT
GGGCGTGGTGGCTATGGGTTATGGCGATGGCTACCCACGAGCGGCGCCTTCCGGTACGCCAGTGCTGGTCAATGGTCGCG
AAGTCCCGATTGTCGGGCGGGTGGCGATGGATATGATTTGCGTGGATTTGGGGCCAAACGCGCAGGATAACGCGGGCGAT
CCGGTGGTCTTATGGGGCGAAGGTCTGCCGGTTGAACGTATCGCTGAAATGACAAAAGTAAGTGCTTACGAACTTATCAC
GCGCCTGACTTCAAGGGTGGCGATGAAGTATATTGATTAA

Protein sequence :
MQAATVVINRRALRHNLQRLRELAPASKLVAVVKANAYGHGLLETARTLPDADAFGVARLEEALRLRAGGITQPILLLEG
FFDAADLPTISAQCLHTAVHNQEQLAALEAVELAEPVTVWMKLDTGMHRLGVRPEEAEAFYQRLTHCKNVRQPVNIVSHF
ARADEPECGATEHQLDIFNAFCQGKPGQRSIAASGGILLWPQSHFDWARPGIILYGVSPLEHKPWGPDFGFQPVMSLTSS
LIAVRDHKAGEPVGYGGTWVSERDTRLGVVAMGYGDGYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPNAQDNAGD
PVVLWGEGLPVERIAEMTKVSAYELITRLTSRVAMKYID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 3e-54 42