Gene Information

Name : thiC (SeSA_A4374)
Accession : YP_002117065.1
Strain : Salmonella enterica CVM19633
Genome accession: NC_011094
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 4246493 - 4248388 bp
Length : 1896 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGTCTACAACAACGTTAACCCGCCGCGAGCAGCGCGCTAAAGCCCAGCATTTTATCGATACGCTGGAAGGCACCGCATT
TCCCAACTCGAAACGCATCTACGTGACCGGTTCGCAGCATGATATTCGCGTACCGATGCGCGAAATTCAACTTAGCCCAA
CGCTCATCGGCGGCAGCAAAGACAACCCGCAGTTTGAAGAGAACGAAGCCGTGCCGGTGTACGACACCTCCGGCCCCTAT
GGCGATCCTGAGGTGGCGATTAACGTCCAGCAGGGTCTGGCGAAACTGCGCCAGCCATGGATTGACGCACGTAACGATAG
CGAAGAATTAGACGACCGTAGCTCGGCTTATACCAGAGAACGTCTGGCCGACGATGGCCTGGACGATCTGCGTTTTACCG
GCCTGCTGACGCCAAAACGCGCTAAAGCGGGCAAGCGCGTCACCCAGTTACACTACGCCCGCAACGGGATCGTCACTCCC
GAAATGGAGTTCATCGCCATCCGTGAAAATATGGGCCGCGAGCGCATTCGCAGTGAAGTACTGCGCCACCAGCATCCGGG
GATGAGCTTTGGCGCACGCCTGCCGGAAAACATCACCCCGGAATTCGTGCGTGATGAAGTCGCCGCCGGACGCGCCATCA
TCCCCGCCAACATCAACCACCCGGAATCGGAGCCGATGATTATTGGCCGCAACTTCCTGGTGAAGGTCAACGCCAATATC
GGCAACTCGGCGGTGACCTCCTCTATCGAAGAAGAGGTGGAAAAACTGGTGTGGGCGACGCGCTGGGGGGCGGATACGGT
AATGGACCTTTCCACCGGGCGCTATATTCACGAAACCCGTGAGTGGATCCTGCGTAATAGCCCAGTACCAATCGGCACGG
TGCCGATCTACCAGGCGCTGGAAAAGGTCAACGGGATCGCCGAGGATCTTACCTGGGAAGCCTTCCGCGACACGCTGCTG
GAGCAGGCCGAACAGGGCGTCGACTACTTCACCATTCACGCGGGCGTGCTGCTGCGTTACGTGCCGATGACCGCCAAGCG
CCTGACCGGCATTGTCTCGCGCGGCGGTTCGATCATGGCGAAGTGGTGTCTCTCCCATCACAAAGAGAACTTCCTGTTCG
AACATTTCCGCGAGATTTGCGAAATCTGCGCCGCCTACGACGTTTCCCTGTCGCTGGGCGACGGCCTGCGACCGGGATCG
ATTCAGGACGCGAACGACGAAGCGCAGTTCTCCGAGCTGCATACGCTGGGCGAGCTGACCAAAATCGCCTGGGAATACGA
CGTGCAGGTGATGATTGAAGGCCCGGGCCACGTGCCGATGCATATGATTCAGCGCAACATGACCGAAGAGCTGGAGCACT
GCCATGAAGCGCCGTTCTACACCTTAGGGCCGCTGACTACCGATATCGCGCCGGGCTATGACCACTTCACCTCCGGCATT
GGCGCGGCGATGATCGGCTGGTTCGGCTGTGCGATGCTGTGTTACGTGACGCCGAAAGAGCATCTCGGCCTGCCGAACAA
AGAAGATGTGAAGCAGGGGCTGATCACCTACAAGATCGCCGCCCACGCCGCTGACTTAGCCAAAGGGCATCCGGGCGCGC
AGATTCGCGATAACGCGATGTCGAAAGCGCGCTTTGAATTCCGCTGGGAGGATCAGTTTAACCTCGCGCTCGACCCGTTC
ACCGCCCGCGCCTGGCACGATGAAACCCTGCCACAGGAGTCCGGCAAAGTGGCGCACTTTTGCTCGATGTGCGGGCCGAA
ATTCTGCTCAATGAAAATCAGCCAGGAAGTTCGTGATTACGCCGCCGCGCAAACTATTGAAGTCGGGATGGCGGATATGT
CGGAAAACTTCCGCGCCAAAGGCGGCGAAATCTATCTCAAGCGGGAGGAAGTCTGA

Protein sequence :
MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPY
GDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRVTQLHYARNGIVTP
EMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANI
GNSAVTSSIEEEVEKLVWATRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLL
EQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGS
IQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGI
GAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPF
TARAWHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRAKGGEIYLKREEV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 72
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 72
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 70