Gene Information

Name : hemC (SeSA_A4151)
Accession : YP_002116870.1
Strain : Salmonella enterica CVM19633
Genome accession: NC_011094
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 4024366 - 4025307 bp
Length : 942 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTTAGACAATGTTTTAAGAATTGCCACACGCCAAAGTCCCCTTGCGCTTTGGCAGGCACATTATGTCAAAGACGCATT
GATGGCAACCCATCCGGGACTGACGGTAGAACTGGTGCCGATGGTCACACGCGGCGACGTGATTCTCGATACTCCCCTGG
CGAAAGTGGGCGGTAAGGGACTGTTTGTTAAAGAGCTTGAAATCGCGCTGCTGGAAAAGCGCGCTGATATCGCCGTGCAC
TCTATGAAAGACGTTCCGGTGGCCTTCCCGGATGGTCTCGGTCTGGTGACCATTTGCGAGCGCGAAGATCCGCGCGACGC
GTTTGTCTCGAATAAATATCACAGTCTGGACGATCTGCCCGCGGGTAGTATCGTCGGGACGTCCAGTTTGCGTCGTCAGT
GTCAACTGGCGGAGCGCCGTCCGGACCTCATTATCCGTTCGTTGCGCGGCAACGTCGGCACACGTCTCGGCAAGCTGGAC
AACGGCGACTATGACGCCATTATCCTGGCCGTGGCCGGTCTGAAACGCTTAGGTCTGGAGTCGCGCATTCGCACAGCCTT
GCCGCCCGACGTTTCACTTCCTGCCGTAGGCCAGGGCGCCGTCGGGATTGAGTGTCGTCTTGACGACGCGCGAACGCAGG
CGCTGCTCGCACCGTTGAATCACTCGCAAACCGCGCTACGCGTAACGGCGGAACGCGCTATGAACACCCGCCTGGAAGGC
GGTTGTCAGGTGCCGATTGGCAGCTATGCAGAAATCATCAACGGTGAAATTTGGTTACGCGCGCTGGTTGGCGCGCCGGA
CGGTTCGGTGATGGTGCGCGGCGAACGTCGTGGTTCTCCCGAGCAGGCGGAGCAAATGGGCATCTCGCTTGCAGAGGAAC
TGCTGGAAAACGGCGCGCGCGCGATTCTGACGGAAGTTTATAACGGCGAGACGCCCGCATGA

Protein sequence :
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKGLFVKELEIALLEKRADIAVH
SMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLD
NGDYDAIILAVAGLKRLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGARAILTEVYNGETPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-86 61
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-86 61