Gene Information

Name : serS (SeSA_A1077)
Accession : YP_002114015.1
Strain : Salmonella enterica CVM19633
Genome accession: NC_011094
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1052302 - 1053594 bp
Length : 1293 bp
Strand : +
Note : 'catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA'

DNA sequence :
ATGCTCGATCCCAATCTGCTGCGTAATGAGCCAGACGCAGTCGCTGAAAAACTGGCACGCCGGGGCTTTAAGCTGGATGT
AGATAAGCTGCGCGCTCTTGAAGAGCGTCGTAAAGTTTTGCAGGTCAACACGGAAAACCTGCAGGCGGAGCGTAATTCTC
GATCGAAATCCATCGGCCAGGCGAAAGCGCGCGGGGAAGATATCGAGCCTTTACGCCTGGAAGTGAATAAACTGGGCGAA
GAGCTGGATGCGGCGAAAGCCGAGCTGGATACCTTGCTGGCGGAGATCCGCAATATCGCGCTGACCATCCCAAACCTGCC
TGCGGATGAAGTGCCGGTAGGTAAAGATGAAAACGACAACGTTGAAGTCAGCCGCTGGGGTACCCCGCGTGAGTTTGATT
TTGAAATCCGCGATCACGTCACCTTAGGGGAAATGCACTCCGGCCTCGACTTTGCCGCCGCGGTTAAGCTGACCGGCTCC
CGTTTTGTAGTGATGAAAGGACAGATTGCGCGTATGCATCGCGCATTGTCGCAGTTCATGTTGGATCTGCATACGGAACA
GCACGGCTATAGCGAAAACTACGTGCCGTATCTGGTTAACCACGACACGCTGTATGGCACCGGTCAACTGCCGAAATTCG
CAGGCGATTTGTTCCATACCCGTCCGCTGGAAGAAGAAGCAGACAGCAGCAACTATGCTTTGATCCCGACGGCGGAGGTT
CCGCTGACCAATCTGGTACGCGATGAAATCATCGACGAAGATCAGCTGCCAATTAAAATGACGGCGCATACGCCTTGTTT
CCGTTCTGAAGCAGGTTCTTATGGTCGTGATACCCGTGGCCTGATTCGTATGCATCAGTTTGACAAAGTGGAAATGGTGC
AGATCGTTCGCCCGGAAGATTCTATGGCTGCGTTGGAAGAGATGACCGGTCACGCGGAAAAAGTGCTCCAGCTACTGGGA
CTGCCGTACCGTAAAATTATTCTGTGCACTGGTGATATGGGCTTCGGCGCCTGCAAAACCTATGACCTCGAAGTCTGGGT
TCCGGCGCAGAATACCTACCGCGAGATCTCTTCCTGCTCTAACGTCTGGGACTTCCAGGCGCGTCGTATGCAGGCACGCT
GTCGCAGCAAGTCCGACAAAAAGACCCGTCTGGTCCATACCCTGAATGGTTCTGGTCTGGCGGTAGGTCGTACCCTGGTG
GCCGTGATGGAAAACTATCAGCAGGCTGATGGTCGCATTGAAGTGCCGGAAGTATTACGTCCGTACATGAACGAACTGGA
ATATATCGGCTAA

Protein sequence :
MLDPNLLRNEPDAVAEKLARRGFKLDVDKLRALEERRKVLQVNTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGE
ELDAAKAELDTLLAEIRNIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEIRDHVTLGEMHSGLDFAAAVKLTGS
RFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNHDTLYGTGQLPKFAGDLFHTRPLEEEADSSNYALIPTAEV
PLTNLVRDEIIDEDQLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLG
LPYRKIILCTGDMGFGACKTYDLEVWVPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLV
AVMENYQQADGRIEVPEVLRPYMNELEYIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 8e-107 56