Gene Information

Name : merA (SeSA_B0045)
Accession : YP_002112925.1
Strain :
Genome accession: NC_011092
Putative virulence/resistance : Resistance
Product : putative mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.16.1.1
Position : 41334 - 43028 bp
Length : 1695 bp
Strand : -
Note : identified by match to protein family HMM PF00070; match to protein family HMM PF00403; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR02053

DNA sequence : 
ATGAGCACTCTCAAAATCACCGGCATGACTTGCGACTCGTGCGCAGTGCATGTCAAGGACGCCCTGGAGAAAGTGCCCGG
CGTGCAATCAGCGGATGTCTCCTACGCCAAGGGCAGCGCCAAGCTCGCCATTGAGGTCGGCACGTCACCCGACGCGCTGA
CGGCCGCTGTAGCTGGACTCGGTTATCGGGCCACGCTGGCCGATGCCCCCTCAGTTTCGACGCCGGGCGGATTGCTCGAC
AAGATGCGCGATCTGCTGGGCAGAAACGACAAGACGGGTAGCAGCGGCGCATTGCATATCGCCGTCATCGGCAGCGGCGG
GGCCGCGATGGCAGCGGCGCTGAAGGCCGTCGAGCAAGGCGCACGTGTCACGCTGATCGAGCGCGGCACCATCGGCGGCA
CCTGCGTCAATGTCGGTTGTGTGCCGTCCAAGATCATGATCCGCGCCGCCCATATCGCCCATCTGCGCCGGGAAAGCCCG
TTCGATGGCGGCATCGCCGCTACCACGCCGACCATCCAGCGCACGGCGCTGCTGGCCCAGCAGCAGGCCCGCGTCGATGA
ACTGCGCCACGCCAAGTACGAAGGCATCTTGGAGGGCAATCCGGCGATCACTGTGCTGCACGGCTCCGCCCGCTTTAAGG
ACAATCGCAACCTGATCGTGCAACTCAACGACGGCGGCGAGCGCGTGGTGGCATTCGACCGCTGCCTGATCGCCACCGGC
GCGAGCCCGGCCGTGCCGCCGATTCCCGGCCTGAAAGACACTCCGTACTGGACTTCCACTGAAGCGCTGGTCAGCGAGAC
GATTCCTAAGCGCCTGGCCGTGATTGGCTCATCAGTGGTGGCGCTGGAGCTGGCGCAGGCGTTCGCCCGACTCGGAGCGA
AGGTGACGATCCTGGCTCGCAGCACGCTGTTCTTCCGCGAAGACCCAGCTATAGGCGAAGCCGTCACGGCCGCATTCCGC
ATGGAGGGCATCGAGGTGAGGGAACACACCCAGGCCAGCCAGGTCGCGTATATCAATGGTGAAGGGGACGGCGAATTCGT
GCTCACCACGGCGCACGGCGAACTGCGCGCCGACAAGCTGCTGGTCGCCACCGGCCGCGCGCCCAACACACGCAAGCTGG
CACTGGATGCGACGGGCGTCACGCTCACCCCGCAAGGCGCTATCGTCATCGACCCCGGCATGCGTACAAGCGTGGAACAC
ATCTACGCCGCAGGCGACTGCACCGACCAGCCGCAGTTCGTCTATGTGGCGGCAGCGGCCGGCACTCGCGCCGCGATCAA
CATGACCGGCGGTGACGCGGCCCTGAACCTGACCGCGATGCCGGCCGTGGTGTTCACCGACCCGCAAGTGGCGACCGTAG
GCTACAGCGAGGCGGAAGCGCACCATGACGGCATCAAAACTGATAGTCGCACGCTAACGCTGGACAACGTGCCGCGCGCG
CTCGCCAACTTCGACACGCGCGGCTTCATCAAACTGGTGGTTGAAGAAGGCAGCGGACGACTGATCGGCGTGCAGGCAGT
GGCCCCGGAAGCGGGCGAACTGATCCAGACGGCCGCACTGGCGATTCGCAACCGGATGACGGTGCAGGAACTGGCCGACC
AGTTGTTCCCCTACCTGACGATGGTCGAAGGGTTGAAGCTCGCGGCGCAGACCTTCAACAAGGATGTGAAGCAGCTTTCC
TGCTGCGCCGGGTGA

Protein sequence : 
MSTLKITGMTCDSCAVHVKDALEKVPGVQSADVSYAKGSAKLAIEVGTSPDALTAAVAGLGYRATLADAPSVSTPGGLLD
KMRDLLGRNDKTGSSGALHIAVIGSGGAAMAAALKAVEQGARVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRESP
FDGGIAATTPTIQRTALLAQQQARVDELRHAKYEGILEGNPAITVLHGSARFKDNRNLIVQLNDGGERVVAFDRCLIATG
ASPAVPPIPGLKDTPYWTSTEALVSETIPKRLAVIGSSVVALELAQAFARLGAKVTILARSTLFFREDPAIGEAVTAAFR
MEGIEVREHTQASQVAYINGEGDGEFVLTTAHGELRADKLLVATGRAPNTRKLALDATGVTLTPQGAIVIDPGMRTSVEH
IYAAGDCTDQPQFVYVAAAAGTRAAINMTGGDAALNLTAMPAVVFTDPQVATVGYSEAEAHHDGIKTDSRTLTLDNVPRA
LANFDTRGFIKLVVEEGSGRLIGVQAVAPEAGELIQTAALAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFNKDVKQLS
CCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AFG30120.1 MerA Not tested PAGI-2 Protein 0.0 100
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 0.0 100
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 0.0 100
merA ABQ57371.1 MerA Not tested SGI1 Protein 0.0 92
merA AGK07021.1 MerA Not tested SGI1 Protein 0.0 92
merA AGK07079.1 MerA Not tested SGI1 Protein 0.0 92
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 0.0 85
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 0.0 85
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 0.0 79
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 0.0 76

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA YP_002112925.1 putative mercuric reductase BAC0652 Protein 0.0 86
merA YP_002112925.1 putative mercuric reductase BAC0653 Protein 0.0 81
merA YP_002112925.1 putative mercuric reductase BAC0650 Protein 5e-170 70