Gene Information

Name : thiC (SeHA_C4494)
Accession : YP_002048149.1
Strain : Salmonella enterica SL476
Genome accession: NC_011083
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 4375891 - 4377786 bp
Length : 1896 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGTCTACAACAACGTTAACCCGCCGCGAGCAGCGCGCTAAAGCCCAGCATTTTATCGATACGCTGGAAGGCACCGCGTT
TCCCAACTCGAAACGCATCTACGTGACCGGTTCGCAGCATGATATTCGCGTACCGATGCGCGAAATTCAACTTAGCCCCA
CGCTCATCGGCGGCAGTAAAGACAACCCGCAGTTTGAAGAGAACGAAGCCGTACCGGTATACGACACCTCCGGCCCCTAT
GGCGATCCTGAGGTGGCGATTAACGTCCAGCAGGGTCTGGCGAAACTGCGCCAGCCATGGATTGACGCACGTAACGATAG
CGAAGAATTAGACGACCGTAGCTCGGCTTATACCAGAGAACGTCTGGCCGACGATGGCCTGGACGATCTGCGCTTTACCG
GCCTGCTGACGCCAAAACGCGCTAAAGCGGGCAAGCGCGTCACCCAGTTACACTACGCCCGCAAGGGGATCGTCACTCCC
GAAATGGAGTTCATCGCCATCCGTGAAAACATGGGCCGCGAACGCATTCGTAGTGAAGTGCTGCGCCACCAGCATCCGGG
GATGAGCTTTGGCGCGCGCCTGCCGGAAAACATTACGCCGGAATTCGTGCGTGATGAAGTCGCCGCGGGCCGCGCGATTA
TTCCCGCCAACATCAACCACCCGGAATCGGAGCCGATGATTATCGGCCGCAACTTCCTGGTCAAAGTGAATGCCAACATC
GGTAACTCGGCGGTGACCTCCTCTATCGAAGAAGAGGTGGAAAAACTGGTGTGGTCAACCCGCTGGGGCGCGGATACGGT
TATGGACCTCTCCACCGGCCGCTATATCCACGAAACCCGCGAATGGATCCTGCGTAACAGCCCGGTACCGATCGGCACCG
TCCCGATCTACCAGGCGCTGGAGAAGGTCAACGGGATCGCCGAAGATCTTACCTGGGAAGCGTTCCGCGACACGCTGCTG
GAGCAGGCCGAACAGGGCGTCGACTACTTCACCATTCACGCGGGCGTGCTGTTGCGCTACGTGCCGATGACCGCCAAACG
CCTGACCGGGATTGTCTCGCGCGGCGGTTCGATCATGGCGAAGTGGTGCCTCTCGCATCACAAAGAGAACTTCCTGTTCG
AACATTTCCGCGAGATCTGCGAAATCTGCGCCGCCTACGACGTTTCCCTGTCGTTAGGCGACGGCCTGCGCCCCGGCTCC
ATTCAGGACGCCAACGACGAAGCGCAGTTCTCCGAGCTGCATACGCTGGGCGAGCTGACCAAAATCGCCTGGGAATACGA
CGTGCAGGTGATGATTGAAGGCCCGGGTCATGTACCCATGCATATGATTCAGCGCAACATGACCGAAGAGCTGGAGAGCT
GCCATGAAGCACCGTTCTACACCTTAGGGCCATTGACCACCGATATCGCGCCGGGCTATGACCACTTCACCTCCGGCATT
GGCGCCGCGATGATCGGCTGGTTCGGTTGTGCGATGCTGTGTTACGTCACGCCGAAAGAGCATCTCGGCCTGCCGAACAA
AGAAGATGTGAAGCAGGGGCTGATCACCTACAAAATAGCCGCCCACGCCGCTGACTTAGCGAAAGGCCATCCGGGCGCGC
AGATCCGCGATAACGCCATGTCGAAAGCGCGCTTCGAATTCCGCTGGGAAGATCAGTTTAACCTCGCGCTCGACCCGTTC
ACCGCCCGCGCTTATCACGATGAAACCCTACCGCAGGAGTCCGGTAAGGTCGCTCACTTCTGTTCCATGTGCGGGCCGAA
GTTCTGCTCGATGAAAATCAGCCAGGAAGTCCGCGACTATGCCGCCGCACAAACCATCGAAGTCGGCATGGCGGATATGT
CGGAAAACTTCCGCGCCAAAGGCGGCGAAATCTATCTCAAGCGGGAGGAAGCCTGA

Protein sequence :
MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPY
GDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRVTQLHYARKGIVTP
EMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANI
GNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLL
EQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGS
IQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGI
GAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPF
TARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRAKGGEIYLKREEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 72
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 72
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 70