Gene Information

Name : hemC (SeHA_C4268)
Accession : YP_002047954.1
Strain : Salmonella enterica SL476
Genome accession: NC_011083
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 4154979 - 4155935 bp
Length : 957 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGACGGTAACAAGCATGTTAGACAATGTTTTAAGAATTGCCACACGCCAAAGTCCCCTTGCGCTTTGGCAGGCACATTA
TGTCAAAGACGCATTGATGGCAACCCATCCGGGACTGACGGTAGAACTGGTGCCGATGGTCACACGCGGCGACGTGATTC
TCGATACTCCCCTGGCGAAAGTGGGCGGTAAGGGACTGTTTGTTAAAGAGCTTGAAATCGCGCTGCTGGAAAAACGCGCT
GATATCGCCGTGCACTCTATGAAAGACGTTCCGGTGGCCTTCCCGGACGGTCTCGGTCTGGTGACCATTTGCGAGCGCGA
AGATCCGCGCGACGCGTTTGTCTCGAATAAATATCACAGTCTGGACGATCTGCCCGCGGGTAGTATCGTCGGGACGTCCA
GTTTGCGTCGCCAGTGTCAACTGGCGGAACGCCGTCCGGACCTCATTATCCGTTCGTTGCGCGGCAACGTCGGCACACGT
CTCGGCAAGCTGGACAACGGCGACTATGACGCCATTATCCTGGCCGTGGCCGGTCTGAAACGCTTAGGTCTGGAGTCGCG
CATTCGCACAGCCTTGCCGCCCGACGTTTCGCTTCCTGCCGTAGGCCAGGGCGCCGTCGGGATTGAGTGTCGTCTTGACG
ACGCGCGAACACAGGCGCTGCTCGCACCGTTGAATCACTCGCAAACCGCGCTACGCGTAACGGCGGAACGCGCTATGAAC
ACCCGCCTGGAAGGCGGATGTCAGGTGCCGATTGGCAGCTATGCAGAAATCATCAACGGTGAAATTTGGCTACGCGCGCT
GGTTGGCGCGCCGGACGGTTCGGTGATGGTGCGCGGCGAACGTCGTGGTTCTCCCGAGCAGGCGGAGCAAATGGGCATCT
CGCTTGCAGAGGAACTGCTGGAAAACGGCGCACGCGCGATTCTGACGGAAGTTTATAACGGCGAGACGCCCGCATGA

Protein sequence : 
MTVTSMLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKGLFVKELEIALLEKRA
DIAVHSMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTR
LGKLDNGDYDAIILAVAGLKRLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMN
TRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGARAILTEVYNGETPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-86 61
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-86 61