Gene Information

Name : thyA (SeHA_C3214)
Accession : YP_002046971.1
Strain : Salmonella enterica SL476
Genome accession: NC_011083
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 3140655 - 3141449 bp
Length : 795 bp
Strand : -
Note : 'ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived'

DNA sequence :
ATGAAACAGTATTTAGAACTGATGCAAAAAGTGCTGGATGAAGGCACACAGAAAAACGACCGTACCGGCACCGGCACGCT
TTCCATTTTTGGCCATCAGATGCGTTTTAACCTGCAGGAAGGCTTTCCTCTGGTGACGACAAAACGCTGCCATTTACGTT
CAATTATTCACGAACTGCTATGGTTTTTGCAGGGCGATACCAACATCGCTTACCTGCACGAAAATAATGTCACCATCTGG
GACGAATGGGCCGATGAGAACGGCGATTTAGGCCCGGTTTATGGTAAGCAGTGGCGTGCATGGCCAACACCGGATGGCCG
CCATATCGATCAGATCGCCACGGTCTTAAGCCAGCTTAAAAACGACCCGGACTCTCGCCGTATTATCGTTTCTGCGTGGA
ACGTCGGCGAGCTGGATAAGATGGCGCTGGCGCCGTGTCACGCCTTTTTCCAGTTTTATGTCGCAGATGGAAAACTCTCC
TGTCAGCTTTATCAGCGCTCCTGCGATGTGTTCCTCGGTCTGCCGTTCAACATTGCCAGCTACGCGTTACTGGTGCATAT
GATGGCGCAACAGTGCGACCTGGACGTCGGCGATTTTGTCTGGACCGGCGGCGACACGCACCTGTACAGCAACCATATGG
AGCAGACGCACCTGCAATTAAGCCGTGAACCGCGCGCGCTGCCGAAATTGGTCATTAAGCGTAAACCCGATTCGCTTTTT
GACTACCGGTTCGATGATTTCGAAATTGAAGGCTATGATCCGCACCCCGGTATTAAAGCGCCGGTCGCTATCTAA

Protein sequence :
MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQEGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIW
DEWADENGDLGPVYGKQWRAWPTPDGRHIDQIATVLSQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLDVGDFVWTGGDTHLYSNHMEQTHLQLSREPRALPKLVIKRKPDSLF
DYRFDDFEIEGYDPHPGIKAPVAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-88 66