Gene Information

Name : SeHA_C3086 (SeHA_C3086)
Accession : YP_002046856.1
Strain : Salmonella enterica SL476
Genome accession: NC_011083
Putative virulence/resistance : Virulence
Product : invasion protein InvA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4789
EC number : -
Position : 3012914 - 3014971 bp
Length : 2058 bp
Strand : -
Note : identified by match to protein family HMM PF00771; match to protein family HMM TIGR01399

DNA sequence :
GTGCTGCTTTCTCTACTTAACAGTGCTCGTTTACGACCTGAATTACTGATTCTGGTACTAATGGTGATGATCATTTCTAT
GTTCGTCATTCCATTACCTACCTATCTGGTTGATTTCCTGATCGCACTGAATATCGTACTGGCGATATTGGTGTTTATGG
GGTCGTTCTACATTGACAGAATCCTCAGTTTTTCAACGTTTCCTGCGGTACTGTTAATTACCACGCTCTTTCGTCTGGCA
TTATCAATCAGTACCAGCCGTCTTATCTTGATTGAAGCCGATGCCGGTGAAATTATCGCCACGTTCGGGCAATTCGTTAT
TGGCGATAGCCTGGCGGTGGGTTTTGTTGTCTTCTCTATTGTCACCGTGGTCCAGTTTATCGTTATTACCAAAGGTTCAG
AACGCGTCGCGGAAGTCGCGGCCCGATTTTCTCTGGATGGTATGCCCGGTAAACAGATGAGTATTGATGCCGATTTGAAG
GCCGGTATTATTGATGCGGATGCCGCGCGCGAACGGCGAAGCGTACTGGAAAGAGAAAGCCAGCTTTACGGTTCCTTTGA
CGGTGCGATGAAGTTTATCAAAGGTGACGCTATTGCCGGCATCATTATCATCTTTGTGAACTTTATTGGCGGTATTTCGG
TGGGGATGACCCGCCATGGTATGGATTTGTCCTCCGCCCTGTCTACTTATACCATGCTGACCATTGGTGATGGTCTTGTC
GCCCAGATCCCCGCATTGTTGATTGCGATTAGTGCCGGTTTTATCGTGACTCGCGTAAATGGCGATAGCGATAATATGGG
GCGGAATATCATGACGCAGCTGTTGAACAACCCATTTGTATTGGTTGTTACGGCTATTTTGACCATTTCAATGGGAACTC
TGCCGGGATTCCCGCTGCCGGTTTTTGTTATTTTATCGGTGGTTTTAAGCGTACTCTTCTATTTTAAATTCCGTGAAGCA
AAACGTAGTGCCGCCAAACCTAAAACCAGCAAAGGCGAGCAGCCGCTCAGTATTGAGGAAAAAGAAGGGTCGTCGTTAGG
ACTGATTGGCGATCTCGATAAAGTCTCTACAGAGACCGTACCGTTGATATTACTTGTGCCGAAGAGCCGGCGTGAAGATC
TGGAAAAAGCTCAACTTGCGGAGCGTCTACGTAGTCAGTTCTTTATTGATTATGGCGTGCGCCTGCCGGAAGTATTGTTA
CGCGATGGCGAGGGCCTGGACGATAACAGCATCGTATTGTTGATTAATGAGATCCGTGTTGAACAATTTACGGTCTATTT
TGATTTGATGCGAGTGGTAAATTATTCCGATGAAGTTGTTTCCTTTGGCATTAATCCAACAATCTATCAGCAAGGTAGCA
GCCAGTATTTCTGGGTAACGCATGAAGAGGGGGAGAAACTCCGGGAGCTTGGCTATGTGTTGCGGAACGCGCTTGATGAG
CTTTACCACTGTCTGGCGGTGACGCTGGCGCGCAACGTCAATGAATATTTCGGTATTCAGGAAACAAAACATATGCTGGA
CCAACTGGAAGCGAAATTTCCTGATTTACTTAAAGAAGTGCTCAGACATGCCACGGTACAACGTATATCTGAAGTTTTGC
AGCGTTTGTTAAGCGAACGTGTTTCCGTGCGTAATATGAAATTAATTATGGAAGCGCTCGCATTGTGGGCGCCAAGAGAA
AAAGATGTCATTAACCTTGTGGAGCATATTCGTGGGGCAATGGCGCGTTATATTTGCCATAAATTCGCCAATGGCGGCGA
ATTACGAGCAGTAATGGTATCTGCTGAAGTTGAGGATGTTATTCGCAAAGGGATCCGTCAGACCTCTGGCAGTACCTTCC
TCAGCCTTGACCCGGAAGCCTCCGCTAATTTGATGGATCTCATTACACTTAAGTTGGATGATTTATTGATTGCACATAAA
GATCTTGTCCTCCTTACGTCTGTCGATGTCCGTCGATTTATTAAGAAAATGATTGAAGGTCGTTTTCCGGATCTGGAGGT
TTTATCTTTCGGTGAGATAGCAGATAGCAAGTCAGTGAATGTTATAAAAACAATATAA

Protein sequence :
MLLSLLNSARLRPELLILVLMVMIISMFVIPLPTYLVDFLIALNIVLAILVFMGSFYIDRILSFSTFPAVLLITTLFRLA
LSISTSRLILIEADAGEIIATFGQFVIGDSLAVGFVVFSIVTVVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLK
AGIIDADAARERRSVLERESQLYGSFDGAMKFIKGDAIAGIIIIFVNFIGGISVGMTRHGMDLSSALSTYTMLTIGDGLV
AQIPALLIAISAGFIVTRVNGDSDNMGRNIMTQLLNNPFVLVVTAILTISMGTLPGFPLPVFVILSVVLSVLFYFKFREA
KRSAAKPKTSKGEQPLSIEEKEGSSLGLIGDLDKVSTETVPLILLVPKSRREDLEKAQLAERLRSQFFIDYGVRLPEVLL
RDGEGLDDNSIVLLINEIRVEQFTVYFDLMRVVNYSDEVVSFGINPTIYQQGSSQYFWVTHEEGEKLRELGYVLRNALDE
LYHCLAVTLARNVNEYFGIQETKHMLDQLEAKFPDLLKEVLRHATVQRISEVLQRLLSERVSVRNMKLIMEALALWAPRE
KDVINLVEHIRGAMARYICHKFANGGELRAVMVSAEVEDVIRKGIRQTSGSTFLSLDPEASANLMDLITLKLDDLLIAHK
DLVLLTSVDVRRFIKKMIEGRFPDLEVLSFGEIADSKSVNVIKTI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
invA NP_457290.1 possible secretory protein (associated with virulence) Virulence SPI-1 Protein 0.0 99
invA NP_806499.1 virulence-associated secretory protein Virulence SPI-1 Protein 0.0 99
invA NP_461817.1 needle complex export protein Virulence SPI-1 Protein 0.0 99
invA YP_217815.1 invasion protein Virulence SPI-1 Protein 0.0 99
ECs3731 NP_311758.1 EivA Not tested LIM Protein 1e-178 65
invA AAS66860.1 InvA Not tested SSR-2 Protein 1e-165 64
ysaV AAS66840.1 YsaV Not tested SSR-1 Protein 3e-143 55
lssD AAO18050.1 LssD Virulence TTSS locus Protein 9e-97 41
YPO0266 YP_002345347.1 secretion system apparatus protein SsaV Virulence Not named Protein 4e-88 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SeHA_C3086 YP_002046856.1 invasion protein InvA VFG0557 Protein 0.0 99
SeHA_C3086 YP_002046856.1 invasion protein InvA VFG1006 Protein 2e-171 65
SeHA_C3086 YP_002046856.1 invasion protein InvA VFG1780 Protein 4e-144 54
SeHA_C3086 YP_002046856.1 invasion protein InvA VFG0384 Protein 1e-98 43
SeHA_C3086 YP_002046856.1 invasion protein InvA VFG0064 Protein 1e-97 43
SeHA_C3086 YP_002046856.1 invasion protein InvA VFG0198 Protein 1e-93 42