Gene Information

Name : murD (SeHA_C0138)
Accession : YP_002044096.1
Strain : Salmonella enterica SL476
Genome accession: NC_011083
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 142599 - 143915 bp
Length : 1317 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGGCTGATTACCAGGACAAAAACGTCGTCATTATTGGTCTGGGCTTAACCGGACTCTCTTGCGTGGACTTTTTTCTCGC
CCGCGGCGTGACGCCGCGGGTGATGGATACTCGCGTGACGCCGCCGGGTCTGGATAAGCTGCCGCAAGAGGTTGAGCGTC
ACGTTGGCGGCCTGAACGACGAGTGGCTCTTAGCGGCGGATTTAATCGTCGCCAGCCCTGGTATTGCTCTGGCACATCCC
TCTCTTAGCGCTGCCGCCAGCGCTGGAGTGGAAATTGTCGGCGATATCGAACTGTTTTGCCGCGAAGCGCAAGCGCCGAT
TGTGGCCATCACCGGCTCGAACGGCAAAAGCACCGTGACCACCTTAGTGGGCGAGATGGCGAAAGCGGCGGGCGTCAATG
TCGGCGTTGGCGGCAATATCGGTCTTCCGGCGCTGATGCTGCTGGATGCCGATCGCGAATTGTACGTGCTGGAATTATCC
AGTTTCCAACTGGAAACTACCTCAAGTTTGCAAGCGGCGGCGGCAACGGTGCTCAACGTCACTGAAGATCATATGGACCG
GTATCCGTTTGGTTTGCAACAGTACCGGGCGGCGAAACTGCGCGTCTACGAGAAGGCGAAAGTGTGCGTAGTGAATGCCG
ATGACGCGTTGACGATGCCGGTACGCGGGGCCGATGAACGCTGCGTTAGCTTTGGCGTCAATATGGGCGATTATCACCTT
AATCGTCAGCAGGGCGAAACCTGGCTGCGAGTCAAAGGCGAGAAGGTGCTGAACGTGAAAGAGATGAAGCTTTCCGGTCA
GCATAACTATACCAATGCGTTAGCGGCGCTGGCGCTGGCGGATGCCGTAGGTCTGCCGCGCGCCAGCAGTTTGAAGGCGT
TGACGACATTTACCGGTCTGGCGCATCGCTTCCAGCTGGCGTTGGAGCATAACGGCGTACGTTGGATCAACGACTCGAAA
GCGACCAACGTCGGCAGTACCGAAGCGGCGCTAAACGGTTTGCATGTGGACGGTACGCTACATCTGCTGCTGGGCGGCGA
CGGTAAGTCGGCAGACTTTTCTCCGCTGACACGCTATCTGACCGGCGATCGTATCCGCCTGTATTGCTTTGGGCGCGATG
GCGCGCAGCTTGCCGCACTGCGTCCGGAAATCGCCCAACAGACTGAGACGATGGAAGAGGCGATGCGTTTGCTGGCGCCG
CGCGTTCAGCCGGGTGATATGGTGCTGCTGTCGCCCGCTTGCGCTAGCCTCGATCAGTTTAAAAATTTTGAGCAACGGGG
CGATGTCTTTACCCGTCTGGCGAAGGAGTTAGGTTGA

Protein sequence :
MADYQDKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRVTPPGLDKLPQEVERHVGGLNDEWLLAADLIVASPGIALAHP
SLSAAASAGVEIVGDIELFCREAQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDADRELYVLELS
SFQLETTSSLQAAAATVLNVTEDHMDRYPFGLQQYRAAKLRVYEKAKVCVVNADDALTMPVRGADERCVSFGVNMGDYHL
NRQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAALALADAVGLPRASSLKALTTFTGLAHRFQLALEHNGVRWINDSK
ATNVGSTEAALNGLHVDGTLHLLLGGDGKSADFSPLTRYLTGDRIRLYCFGRDGAQLAALRPEIAQQTETMEEAMRLLAP
RVQPGDMVLLSPACASLDQFKNFEQRGDVFTRLAKELG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 3e-52 44
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 3e-52 44