Gene Information

Name : serS (SeHA_C1062)
Accession : YP_002044956.1
Strain : Salmonella enterica SL476
Genome accession: NC_011083
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1048183 - 1049475 bp
Length : 1293 bp
Strand : +
Note : 'catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA'

DNA sequence :
ATGCTCGATCCCAATCTGCTGCGTAATGAGCCAGACGCAGTCGCTGAAAAACTGGCACGCCGGGGCTTTAAGCTGGATGT
AGATAAGCTGCGCGCTCTTGAAGAGCGTCGTAAAGTTTTGCAGGTCAACACGGAAAACCTGCAGGCGGAGCGTAATTCTC
GATCGAAATCCATCGGCCAGGCGAAAGCGCGCGGGGAAGATATTGAGCCTTTACGCCTGGAAGTGAATAAACTGGGCGAA
GAGCTGGATGCGGCGAAAGCCGAGCTGGAAACCTTGCTGGCGGAGATCCGCGATATCGCGCTGACCATCCCAAACCTGCC
TGCGGATGAAGTGCCGGTAGGTAAAGATGAAAACGACAACGTTGAAGTCAGCCGCTGGGGTACCCCGCGTGAGTTTGATT
TTGAAATCCGCGATCACGTCACCTTAGGGGAAATGCACTCCGGCCTCGACTTTGCCGCCGCGGTTAAGCTGACCGGCTCC
CGTTTTGTGGTGATGAAAGGACAGATTGCGCGTATGCATCGCGCATTGTCGCAGTTCATGTTGGATCTGCATACGGAACA
GCACGGCTATAGCGAAAACTACGTGCCGTATCTGGTTAACCACGACACGCTGTATGGCACCGGTCAACTGCCGAAATTCG
CAGGCGACTTGTTCCATACCCGTCCGCTGGAAGAAGAAGCAGACAGCAGCAACTATGCTTTGATCCCGACGGCGGAGGTT
CCGCTGACCAATCTGGTACGCGATGAAATCATCGACGAAGATCAGCTGCCGATTAAAATGACGGCGCATACGCCTTGTTT
CCGTTCTGAAGCAGGTTCTTATGGCCGTGATACCCGTGGCCTGATTCGTATGCATCAGTTTGACAAAGTGGAAATGGTGC
AGATCGTTCGCCCGGAAGATTCTATGGCTGCGTTGGAAGAGATGACCGGTCACGCGGAAAAAGTGCTCCAGCTACTGGGA
CTGCCGTACCGTAAAATTATTCTGTGCACTGGCGATATGGGCTTCGGCGCCTGCAAAACCTATGACCTCGAAGTCTGGGT
TCCGGCGCAGAATACCTACCGCGAGATCTCTTCCTGCTCTAACGTCTGGGACTTCCAGGCGCGTCGTATGCAGGCACGCT
GTCGCAGCAAGTCCGACAAAAAGACCCGTCTGGTCCATACCCTGAATGGTTCTGGTCTGGCGGTAGGTCGTACCCTGGTG
GCCGTGATGGAAAACTATCAGCAGGCTGATGGCCGCATTGAAGTGCCGGAAGTATTACGTCCGTACATGAACGGACTGGA
ATATATCGGCTAA

Protein sequence :
MLDPNLLRNEPDAVAEKLARRGFKLDVDKLRALEERRKVLQVNTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGE
ELDAAKAELETLLAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEIRDHVTLGEMHSGLDFAAAVKLTGS
RFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNHDTLYGTGQLPKFAGDLFHTRPLEEEADSSNYALIPTAEV
PLTNLVRDEIIDEDQLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLG
LPYRKIILCTGDMGFGACKTYDLEVWVPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLV
AVMENYQQADGRIEVPEVLRPYMNGLEYIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-103 57