Gene Information

Name : thiC (SNSL254_A4496)
Accession : YP_002043412.1
Strain : Salmonella enterica SL254
Genome accession: NC_011080
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 4370628 - 4372523 bp
Length : 1896 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGTCTACAACAACGTTAACCCGCCGCGAGCAGCGCGCTAAAGCCCAGCATTTTATCGATACGCTGGAAGGCACCGCGTT
TCCCAACTCGAAACGCATCTACGTGACCGGTTCGCAGCATGATATTCGCGTACCGATGCGCGAAATTCAACTTAGCCCCA
CGCTCATCGGCGGCAGTAAAGACAACCCGCAGTTTGAAGAGAACGAAGCCGTACCGGTATACGACACCTCCGGCCCCTAT
GGCGATCCTGAGGTGGCGATTAACGTCCAGCAGGGTCTGGCGAAACTGCGCCAGCCATGGATTGACGCACGTAACGATAG
CGAAGAATTAGACGACCGTAGCTCGGCTTATACCAGAGAACGTCTGGCCGACGATGGCCTGGACGATCTGCGCTTTACCG
GCCTGCTGACGCCAAAACGCGCTAAAGCGGGCAAGCGCGTCACCCAGTTACACTACGCCCGCAAGGGGATCGTCACTCCC
GAAATGGAGTTCATCGCCATCCGTGAAAATATGGGCCGTGAGCGCATTCGCAGTGAAGTGCTGCGCCACCAGCATCCGGG
CATGAACTTTGGCGCGCGCCTACCGGAAAACATTACGCCGGAATTCGTGCGTGATGAAGTCGCCGCGGGCCGCGCGATTA
TCCCTGCCAACATCAACCACCCGGAATCGGAGCCGATGATTATCGGCCGCAACTTCCTGGTCAAAGTGAATGCCAACATC
GGTAACTCGGCGGTCACCTCCTCCATCGAAGAAGAGGTGGAGAAGCTGGTGTGGTCAACGCGCTGGGGCGCAGACACGGT
GATGGATCTCTCCACCGGCCGCTATATCCACGAAACCCGCGAATGGATCCTGCGTAACAGCCCGGTACCGATCGGCACCG
TCCCGATCTACCAAGCGCTGGAGAAGGTCAACGGGATCGCCGAAGATCTTACCTGGGAAGCGTTCCGCGACACGCTGCTG
GAGCAGGCCGAACAGGGCGTCGACTACTTCACCATTCACGCGGGCGTGCTGTTGCGCTACGTGCCGATGACCGCCAAACG
CCTGACCGGTATTGTCTCGCGCGGCGGTTCGATCATGGCGAAGTGGTGCCTCTCGCATCACAAAGAGAACTTCCTGTTCG
AACATTTCCGCGAAATTTGTGAAATCTGCGCCGCCTACGACGTTTCCCTGTCGTTGGGCGACGGCCTGCGCCCCGGCTCC
ATTCAGGACGCCAACGACGAAGCGCAGTTCTCCGAGCTGCATACGCTGGGCGAATTGACCAAAATCGCCTGGGAATACGA
CGTGCAGGTGATGATTGAAGGCCCGGGCCACGTGCCGATGCATATGATTCAGCGCAACATGACCGAAGAGTTGGAGAGCT
GCCACGAAGCGCCGTTCTACACCTTAGGGCCGTTGACCACCGATATCGCGCCGGGCTATGACCACTTTACCTCCGGCATT
GGCGCGGCGATGATCGGCTGGTTTGGCTGCGCGATGCTGTGTTACGTGACGCCGAAAGAACACCTCGGCCTGCCGAACAA
AGAAGATGTGAAGCAGGGGCTGATCACCTACAAAATCGCCGCCCACGCCGCTGACTTAGCGAAAGGCCATCCGGGCGCAC
AGATCCGCGATAACGCCATGTCGAAAGCGCGCTTTGAATTCCGCTGGGAAGACCAGTTTAACCTCGCGCTCGACCCTTTC
ACCGCCCGCGCTTATCACGATGAAACCCTACCGCAGGAGTCCGGTAAGGTCGCTCACTTCTGTTCCATGTGCGGGCCGAA
GTTCTGCTCGATGAAAATCAGCCAGGAAGTCCGCGACTACGCCGCTGCACAAACTATTGAAATCGGCATGGCGGATATGT
CAGAGGACTTCCGCGCCAAAGGCGGCGAAATTTATCTCAAGCGGGAGGAAGCCTGA

Protein sequence :
MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPY
GDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRVTQLHYARKGIVTP
EMEFIAIRENMGRERIRSEVLRHQHPGMNFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANI
GNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLL
EQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGS
IQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGI
GAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPF
TARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEIGMADMSEDFRAKGGEIYLKREEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 72
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 72
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 70