Gene Information

Name : metB (SNSL254_A4431)
Accession : YP_002043364.1
Strain : Salmonella enterica SL254
Genome accession: NC_011080
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 4301340 - 4302500 bp
Length : 1161 bp
Strand : +
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGACGCGTAAACAGGCCACTATCGCAGTGCGTAGCGGATTAAACGATGACGAACAATACGGCTGCGTTGTGCCGCCAAT
TCACCTCTCCAGTACCTATAACTTTACCGGTTTCAATGAGCCGCGCGCGCATGATTATTCCCGCCGCGGTAATCCCACGC
GTGATGTGGTTCAGCGCGCATTAGCGGAACTGGAAGGCGGCGCGGGCGCGGTATTGACGAATACCGGCATGTCGGCGATT
CATCTGGTCACCACCGTTTTCCTCAAGCCGGGCGATCTGCTGGTCGCGCCGCATGATTGCTACGGCGGCAGTTATCGTCT
GTTTGACAGTCTGGCGACACGCGGCTGTTATCGTGTGCGGTTTGTCGATCAGGGCGATGAACGCGCCTTACAGGCGGCGC
TGGAAGAAAAACCGAAGCTGGTACTGGTAGAAAGTCCAAGCAATCCATTGTTACGCGTGGTGGATATTGCGAAAATCTGT
CGGCTGGCGCGCGAGGCGGGCGCAGTGAGCGTCGTTGATAACACGTTTTTAAGCCCGGCGCTGCAAAATCCGCTGGCGTT
GGGTGCCGATCTGGTGTTGCATTCATGCACGAAATATCTCAACGGTCATTCGGATGTCGTGGCCGGCGTGGTGATTGCGA
AAGATCCGGAAGTGGTCACTGAACTGGCGTGGTGGGCGAATAATATTGGCGTGACCGGCGGGGCGTTTGATAGCTATCTG
CTGCTGCGCGGTTTGCGAACTCTGGTGCCGCGTATGGAGCTGGCGCAGCGCAACGCGCAGGCGATTGTGAAATATCTGCA
AACCCAGCCGTTGGTGAAAAAACTGTATCATCCGTCGCTGCCGGAAAATCAGGGGCATGAAATTGCCGCGCGCCAGCAAA
AAGGCTTTGGCGCAATGTTGAGTTTTGAACTGGATGGGGATGAGGAGACGCTGCGTCGTTTTCTGGGCGGGCTGTCGCTG
TTTACGCTGGCGGAATCTTTAGGGGGAGTGGAAAGTTTGATCTCTCACGCCGCCACCATGACGCATGCCGGTATGTCGCC
GCAGGCGCGTGCCTCCGCCGGGATCTCCGAAACGCTACTGCGTATCTCCACCGGTATTGAAGATGGCGAAGATTTAATTG
CCGATCTGGAAAATGGCTTCCGGGCTGCAAACAAGGGGTAA

Protein sequence :
MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAI
HLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLATRGCYRVRFVDQGDERALQAALEEKPKLVLVESPSNPLLRVVDIAKIC
RLAREAGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPEVVTELAWWANNIGVTGGAFDSYL
LLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEETLRRFLGGLSL
FTLAESLGGVESLISHAATMTHAGMSPQARASAGISETLLRISTGIEDGEDLIADLENGFRAANKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-61 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-62 43
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-51 41