Gene Information

Name : topB (SNSL254_A1409)
Accession : YP_002040555.1
Strain : Salmonella enterica SL254
Genome accession: NC_011080
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 1378627 - 1380576 bp
Length : 1950 bp
Strand : +
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCGGTTGTTTATTGCCGAAAAACCGAGTCTGGGGCGCGCCATTGCGGATGTGCTGCCAAAACCGCACCGTAAAGGCGA
TGGTTTTATTGAGTGCGGAAACGGGCAGGTCGTCACCTGGTGTATCGGTCATTTGCTGGAACAGGCGCAGCCGGATGCGT
ATGACAGCCGTTATGCGCGCTGGAATCTGGCTGACCTGCCTATCGTGCCGGAAAAATGGCAGCTTCAGCCTCGTCCTTCC
GTCACCAAACAGCTCAATGTGATTAAGCGCTTTTTGCATCAAGCCGGTGAAATTATTCACGCTGGCGACCCGGATCGCGA
AGGGCAGCTTCTGGTTGATGAAGTGCTGGATTATCTCCAGCTTCCTGCCGAAAAGCGCCAGCAGGTGCGGCGTTGTCTGA
TAAACGACCTTAACCCGCAGGCGGTCGAGCGTGCTATTGACAGGCTGCGGGCGAACAGCGACTTCGTGCCGCTGTGCGTC
TCCGCGCTGGCGCGAGCGCGAGCGGACTGGCTGTATGGCATTAATATGACCCGCGCTTACACGATCCTGGGCCGGAATGC
CGGCTATCAGGGCGTGTTATCCGTGGGACGCGTACAGACTCCGGTACTGGGGCTGGTGGTGCGGCGAGACGAAGAGATTG
AGAACTTCGTCGCCAAAGACTTCTTTGAAGTAAAGGCGCACATCGTTACGCCTGCCGACGAGCGTTTTACCGCTATCTGG
CAGCCGAGCGAGGCGTGCGAACCTTATCAGGATGAAGAGGGGCGCTTGCTTCATCGTCCGCTGGCGGAGCATGTAGTGAA
CCGAATCAACGGTCAGCCCGCGCTGGTAACCAGTTATAATGATAAACGGGAATCAGAATCCGCGCCGCTGCCGTTTTCGC
TCTCGACGCTACAGATTGAAGCCGCCAAACGCTTTGGCCTGAGCGCGCAAAACGTGCTTGATATTTGTCAGAAGCTCTAT
GAAACCCACAAACTGATTACCTATCCGCGTTCCGACTGCCGTTATCTGCCGGAAGAACACTTTGCCGGACGGCAGGCGGT
CATGAACGCGATTAGCGTCCACGCCCCGGATTTACTGCCGCAGCCTGTGGTTAATCCTGATACGCGCAATCGCTGCTGGG
ATGACAAAAAAGTGGATGCGCACCACGCGATTATCCCGACGGCGCGCAGTTCTTCTGTCCATCTGACGGAAAACGAAGCG
AAAGTGTACACCCTGATTGCGCGTCAGTATCTGATGCAGTTCTGCCCGGACGCGGTGTTTCGTAAATGCGTTATTGAACT
GGAAATCGCCAAAGGGAAATTTGTCGCCAAAGCGCGTTTTCTGGCGGAGGCCGGTTGGCGGACGTTACTGGGCAGTAAAG
AGCGCGACGAGGAAAACGACGGTACGCCGCTGCCGGTTGTCGCCAAAGGTGATGAGTTGCTGTGTGAAAAGGGGGAAGTG
GTCGAGCGCCAAACCCAGCCGCCGCGTCATTTTACTGATGCGACATTGCTTTCCGCGATGACCGGAATTGCCCGCTTCGT
GCAGGATAAAGATCTGAAAAAGATCCTGCGCGCGACCGATGGGCTGGGGACGGAAGCCACGCGCGCCGGGATTATCGAGC
TGCTGTTCAAACGTAGCTTTCTGACCAAAAAAGGGCGCTACATTCATTCTACCGATGCTGGCAAAGCGTTAATACATTCG
CTGCCGGAAATGGCGGCCCGTCCAGATATGACCGCGCACTGGGAATCTGTTTTGACGCAAATCAGCGAAAAGCAGTGCCG
TTACCAGGATTTCATGCAACCGCTGGTCGGCACGTTATATCAGCTGATCGAGCAGGCTAAGCGCACGCCGGTGAAGCGCT
TCAGAGGGATAGTCGCGCCAGGCGGTGGAGACAAGAAAAAGAGCGCGCCGCGTAAGCGAGCGGGCAAAAAAAGCCCGCCT
GCTGAGGAGACAGGCCGTCAGACCGAATAA

Protein sequence :
MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPS
VTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCV
SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIW
QPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLY
ETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQPVVNPDTRNRCWDDKKVDAHHAIIPTARSSSVHLTENEA
KVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEV
VERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHS
LPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIEQAKRTPVKRFRGIVAPGGGDKKKSAPRKRAGKKSPP
AEETGRQTE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 3e-103 41
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 2e-110 41