Gene Information

Name : SNSL254_A1191 (SNSL254_A1191)
Accession : YP_002040351.1
Strain : Salmonella enterica SL254
Genome accession: NC_011080
Putative virulence/resistance : Virulence
Product : transcriptional regulatory protein YedW
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 1185973 - 1186653 bp
Length : 681 bp
Strand : -
Note : induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistanc

DNA sequence : 
ATGAAGATTTTATTGATTGAAGATAACCAGAAAACCATTGAGTGGGTACGTCAGGGACTCACGGAAGCAGGCTATGTGGT
TGATTATGCCTGTGATGGACGAGACGGATTACACCTCGCCCTTCAGGAACATTATTCATTGATTATTCTTGATATTATGC
TGCCGGGGCTTGATGGATGGCAGGTTTTACGCGCGTTACGCACTGCGCATCAGTCCCCTGTTATTTGCCTGACGGCGCGC
GACTCGGTTGAGGATCGCGTCAAAGGTCTTGAGGCGGGCGCTAATGATTACCTTGTTAAGCCTTTTTCCTTCGCCGAACT
GCTGGCCCGGGTGAGAGCTCAACTCAGACAGCATGTCCCGGTCTTTACCCGACTGACGATTAATGGTCTGGACATGGATG
CCACAAAGCAATCGGTGTCACGAAATGGCAAACCGATTTCCCTGACCCGCAAAGAATTCCTGCTCCTCTGGTTACTGGCG
TCCCGGGCAGGAGAAATCGTGCCCCGAACCGCGATTGCCAGCGAAGTTTGGGGAATTAACTTTGATAGTGAAACCAACAC
CGTTGATGTCGCGATTCGTCGGCTGCGCGCCAAAGTAGACGATCCATTTGAAAATAAGCTCATTATGACCGTCCGGGGGA
TGGGTTATCGATTACAGGCGGAAGCGTCGCAGAATGGTTAA

Protein sequence : 
MKILLIEDNQKTIEWVRQGLTEAGYVVDYACDGRDGLHLALQEHYSLIILDIMLPGLDGWQVLRALRTAHQSPVICLTAR
DSVEDRVKGLEAGANDYLVKPFSFAELLARVRAQLRQHVPVFTRLTINGLDMDATKQSVSRNGKPISLTRKEFLLLWLLA
SRAGEIVPRTAIASEVWGINFDSETNTVDVAIRRLRAKVDDPFENKLIMTVRGMGYRLQAEASQNG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 1e-102 99
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 8e-102 98

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW BAC0083 Protein 3e-56 58
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW BAC0197 Protein 2e-59 58
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW BAC0125 Protein 1e-59 56
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW BAC0638 Protein 1e-52 56
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW BAC0308 Protein 3e-54 55
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW BAC0111 Protein 4e-57 53
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW BAC0347 Protein 2e-50 51
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW NC_003923.1003417.p0 Protein 1e-39 45
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW NC_013450.8614146.p0 Protein 1e-39 45
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW NC_002951.3238224.p0 Protein 1e-39 45
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW NC_007793.3914065.p0 Protein 1e-39 45
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW NC_002758.1121390.p0 Protein 1e-39 45
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW NC_010079.5776364.p0 Protein 1e-39 45
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW NC_002952.2859858.p0 Protein 1e-39 45
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW NC_007622.3794948.p0 Protein 1e-39 45
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW AE015929.1.gene1106. Protein 2e-33 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW VFG0596 Protein 4e-103 99
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW VFG1389 Protein 4e-32 42
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW VFG0473 Protein 4e-29 41
SNSL254_A1191 YP_002040351.1 transcriptional regulatory protein YedW VFG1390 Protein 5e-38 41