Gene Information

Name : cpsD (SPG_0317)
Accession : YP_002037032.1
Strain : Streptococcus pneumoniae G54
Genome accession: NC_011072
Putative virulence/resistance : Virulence
Product : tyrosine-protein kinase wze
Function : -
COG functional category : D : Cell cycle control, cell division, chromosome partitioning
COG ID : COG0489
EC number : 2.7.10.2
Position : 306664 - 307347 bp
Length : 684 bp
Strand : +
Note : Bentley, S.D.; 2006 PLOS Genetics 2: 0262-0269 Guidolin,A.; 1994 Inf.Imm. 62:5384-5396; identified by match to protein family HMM TIGR01007

DNA sequence :
ATGCCGACATTAGAAATAGCACAAAAAAAACTGGAGTTCGTTAAGAAGGCAGAAGAATATTACAATGCCTTGTGTACAAA
TATACAGTTGAGCGGAGATAAACTAAAAGTAATTTCCGTTACTTCTGTTAACCCTGGGGAAGGAAAAACAACTACTTCCG
TAAATATAGCAAGGTCGTTTGCGCGTGCAGGCTATAAAACTCTTTTGATCGATGGCGATACTCGAAATTCAGTTATGTCA
GGATTTTTTAAATCTCGTGAAAAAATTACAGGGCTAACGGAATTTTTATCTGGGACAGCTGATTTATCTCACGGTTTATG
TGATACAAATATTGAAAATTTATTTGTAGTTCAATCGGGCACTGTATCACCAAACCCTACAGCCTTGTTACAAAGTAAAA
ATTTTAATGATATGATTGAAACATTGCGTAAATATTTTGATTATATCATTGTTGATACAGCACCTATTGGAATTGTTATT
GATGCGGCAATTATCACTCAAAAGTGTGATGCGTCCATCTTGGTAACAGCAACAGGTGAGGTGAATAAACGTGATGTCCA
AAAAGCGAAACAACAATTAGAACAAACAGGGAAACTGTTCCTAGGAGTTGTTTTTAATAAATTAGATATCTCGGTTGATA
AGTATGGAGTTTACGGTTTCTATGGAAATTATGGTAAAAAATAA

Protein sequence :
MPTLEIAQKKLEFVKKAEEYYNALCTNIQLSGDKLKVISVTSVNPGEGKTTTSVNIARSFARAGYKTLLIDGDTRNSVMS
GFFKSREKITGLTEFLSGTADLSHGLCDTNIENLFVVQSGTVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
DAAIITQKCDASILVTATGEVNKRDVQKAKQQLEQTGKLFLGVVFNKLDISVDKYGVYGFYGNYGKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cpsFD YP_006310771.1 putative autophosphorylating protein tyrosine kinase Not tested FWisland_4 Protein 5e-62 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cpsD YP_002037032.1 tyrosine-protein kinase wze VFG1368 Protein 1e-97 94
cpsD YP_002037032.1 tyrosine-protein kinase wze VFG1349 Protein 7e-59 57