Gene Information

Name : tktA (SPG_1943)
Accession : YP_002038610.1
Strain : Streptococcus pneumoniae G54
Genome accession: NC_011072
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : -
Position : 1844975 - 1846951 bp
Length : 1977 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTCAAATCTATCTGTTAATGCAATTCGTTTTCTAGGTATTGACGCCATTAATAAAGCCAACTCAGGTCATCCAGGTGT
GGTTATGGGAGCGGCTCCGATGGCTTACAGCCTCTTTACAAAACAACTTCATATCAATCCAGCTCAACCAAATTGGATTA
ACCGCGACCGCTTTATTCTTTCAGCAGGTCATGGTTCAATGCTCCTTTATGCTCTTCTTCACCTTTCTGGTTTTGAAGAT
GTCAGCATGAATGAGATTAAGAGCTTCCGTCAATGGGGTTCAAAAACACCAGGTCACCCAGAATTTGGTCATACGGCAGG
GATTGATGCTACGACAGGTCCTCTAGGGCAAGGGATTTCAACTGCTACTGGTTTTGCCCAAGCAGAACGTTTCTTGGCAG
CCAAATATAACCGTGAAGGCTACAATATCTTTGACCACTATACTTACGTTATCTGTGGAGACGGAGACTTGATGGAAGGT
GTCTCAAGCGAGGCAGCTTCATACGCAGGTTTGCAAAAACTTGATAAGTTGGTTGTTCTTTATGATTCAAATGATATCAA
CTTGGATGGTGAGACAAAGGATTCCTTTACAGAAAGTGTTCGTGACCGTTACAATGCCTACGGTTGGCATACTGCCTTGG
TTGAAAATGGAACAGACTTGGAAGCCATCCATGCTGCTATCGAAACAGCAAAAGCTTCAGGCAAGCCATCTTTGATTGAA
GTGAAGACGGTTATTGGATACGGTTCTCCAAACAAACAAGGAACTAATGCTGTACACGGCGCCCCTCTTGGAGCAGATGA
AACTGCATCAACTCGCCAAGCCCTCGGTTGGGACTACGAACCATTTGAAATTCCAGAACAAGTATATGCTGATTTCAAAG
AACATGTTGCAGACCGTGGCGCATCAGCTTATCAAGCTTGGACTAAATTAGTTGCAGATTATAAAGAAGTTCATCCAGAA
CTGGCTGCAGAAGTAGAAGCCATCATCGACGGACGTGATCCAGTCGAAGTGACTCCAGCAGACTTCCCAGCTTTAGAAAA
TGGTTTTTCTCAAGCAACTCGTAATTCAAGTCAAGATGCCTTGAATGTTGTGGCAGCTAAATTACCAACCTTCCTAGGTG
GATCAGCTGACCTTGCTCACTCAAACATGACTTATATCAAGACGGATGGACTTCAAGACGATGCCAATCGCTTGAATCGT
AACATTCAGTTTGGTGTTCGTGAATTTGCAATGGGAACAATCTTGAACGGGATGGCCCTTCATGGTGGACTTCGTGTATA
CGGTGGAACTTTCTTCGTCTTCTCTGACTATGTGAAGGCAGCTGTCCGCTTGTCAGCCTTACAAGGACTTCCTGTGACTT
ATGTCTTTACCCATGATTCAATCGCAGTTGGGGAAGATGGTCCGACTCACGAACCAGTTGAGCATTTAGCAGGTCTTCGT
GCTATGCCAAATCTAAATGTTTTCCGTCCAGCAGATGCGCGTGAAACGCAAGCAGCTTGGTACCTTGCAGTGACAAGTGA
GAAAACACCAACTGCCCTTGTCTTGACACGTCAAAACTTGACTGTTGAAGATGGAACAGACTTCGACAAGGTTGCTAAAG
GTGCTTATGTTGTATATGAAAATGCAGCCGACTTTGATACCATCTTGATTGCGACAGGTTCAGAGGTTAATCTTGCTGTC
TCAGCTGCTAAAGAATTGGCTAGTCAAGGCGAAAAAATCCGCGTAGTCAGCATGCCATCTACAGATGTCTTTGATAAACA
AGATGCAGCTTACAAGGAAGAAATTCTTCCAAATGCAGTCCGCCGTCGTGTTGCAGTCGAAATGGGTGCAAGTCAAAACT
GGTACAAATATGTTGGTCTCGATGGTGCCGTTCNAGGTATTGATACCTTCGGAGCCTCTGCCCCAGCACCAAAAGTATTG
GCAGAATATGGCTTTACTGTCGAAAATCTTGTAAAAGTTGTTCGAAATTTGAAATAA

Protein sequence :
MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLHINPAQPNWINRDRFILSAGHGSMLLYALLHLSGFED
VSMNEIKSFRQWGSKTPGHPEFGHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGTDLEAIHAAIETAKASGKPSLIE
VKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALGWDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEVHPE
LAAEVEAIIDGRDPVEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQDDANRLNR
NIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGLPVTYVFTHDSIAVGEDGPTHEPVEHLAGLR
AMPNLNVFRPADARETQAAWYLAVTSEKTPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAV
SAAKELASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAVXGIDTFGASAPAPKVL
AEYGFTVENLVKVVRNLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 5e-154 50
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 5e-147 48