Gene Information

Name : nrdF (SPG_1078)
Accession : YP_002037788.1
Strain : Streptococcus pneumoniae G54
Genome accession: NC_011072
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 1057182 - 1058144 bp
Length : 963 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGGAAACTTACTACAAAGCCATTAACTGGAATGCCATCGAAGATGTCATCGACAAATCAACTTGGGAAAAACTGACGGA
GCAATTTTGGCTCGATACACGTATTCCCTTATCAAACGACTTGGATGACTGGAGAAAGCTATCTAACAAAGAGAAAGACT
TGGTCGGAAAAGTTTTTGGTGGTTTAACCCTTCTTGACACTATGCAATCTGAAACTGGGGTTCAAGCCCTTCGCGCAGAC
ATCCGTACACCACATGAGGAAGCTGTTTTCAATAACATCCAATTTATGGAATCTGTCCACGCTAAATCTTACTCATCAAT
CTTTTCTACCTTGAATACTAAGGCTGAGATTGAAGAAATTTTCGAATGGACCAATACCAATCCTTACCTACAAAAGAAGG
CTGAGATTGTCAACGAAATCTACCTAAACGGCAGCCCACTTGAAAAGAAAGTTGCCAGCGTCTTCCTCGAAACCTTCCTC
TTCTACTCTGGTTTCTTCACTCCCCTCTACTATCTCGGTAACAACAAACTAGCCAACGTTGCAGAAATCATTAAATTGAT
TATTCGTGACGAGTCTGTTCACGGAACCTACATTGGTTACAAATTCCAACTTGGTTTCAATGAATTGCCTGAAGAAGAGC
AAGAAAAACTCAAAGAATGGATGTACGACCTACTCTATACTCTTTATGAAAATGAAGAAGGCTACACAGAGAGTCTTTAT
GACGGTGTTGGTTGGACTGAAGAGGTTAAAACCTTCCTTCGCTACAATGCCAATAAAGCTCTCATGAACATGGGACAAGA
TCCACTTTTCCCAGATTCAGCTGAAGATGTCAACCCAATCGTTATGAACGGTATTTCAACAGGAACTTCCAACCATGACT
TCTTCTCTCAAGTCGGAAATGGTTACCTTCTTGGCGAAGTTGAAGCCATGCAAGACGATGACTATAACTACGGTTTAGAC
TAA

Protein sequence :
METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDWRKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRAD
IRTPHEEAVFNNIQFMESVHAKSYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLKEWMYDLLYTLYENEEGYTESLY
DGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAEDVNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 8e-72 50