Gene Information

Name : Smal_2275 (Smal_2275)
Accession : YP_002028661.1
Strain : Stenotrophomonas maltophilia R551-3
Genome accession: NC_011071
Putative virulence/resistance : Virulence
Product : AMP-dependent synthetase and ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 2554048 - 2555700 bp
Length : 1653 bp
Strand : -
Note : PFAM: AMP-dependent synthetase and ligase; KEGG: mxa:MXAN_3645 2,3-dihydroxybenzoate-AMP ligase

DNA sequence : 
ATGAATACCTCCATTGATTCCTCCCGCCTGCCACTGAAGCAGGTATGGCCCGATGCGCTGGCGGCGCGCTATCGCGAGGC
CGGTCACTGGCGCGGCGAGACCTTCCCGGCATTCCTGCGTGAGCGTGCGGAACGCTATGCGGATGACATCGCGGTGGTCG
CCGGTGATATCCGCCTGAGCTACGCGCAGCTGTGGCACGAAGCCGGTCGCATCGGTTCCGGACTGCTGGCACTCGGCCTG
CAGCCCGGTGAGCGGGTGCTGGTGCAGCTGGGCAACACCGCAGGCTTCATCACCACGGTCTGTGGCCTGTTCCGCGCCGG
ACTGGTGCCGGTATACGCGCTGCCTGCGCATCGCATCACCGAACTGGTGCACTTCGCGAACAAGGCCGAGGCCAGTGCCT
ACATCACTGCCGACCTGCACGACGGCTTTGATCATCGCGGGCTGGCGCGGGCGCTGCAGGCCGAGGTGCCGGCGCTGCGC
CACGTGGTCATCGATGGCGATGCAGCGGAGTTCACCGCGCTGGAGTCGCTGCAGGGCGACCGCAGCCAGCTGCCGGCCGA
TCCGGATCCGCAGTCGGTGGCGTTCCTGCAGATCTCCGGTGGCAGTACCGGGTTGTCCAAGCTGATTCCGCGTACCCACG
ACGACTACATCTATTCGTTCCGCGCCAGCAATGACATCTGCGGCATCGACCGCGACAGCGTGTATCTGGTCGCGCTGCCG
GCCGCGCACAATTTCCCGATGAGCTCGCCCGGCTTCTTCGGCGCGCTGTATGCAGGCGCCCGCGTAGTGCTCAGCCCCGG
CCCCGGCCCGGATGCGGCGTTCCCGTTGATCGCCCGCGAGCGCGTGACCTGCTGTGGCCTGGTGCCGCCGCTGGCGCTGC
TGTGGGCACAGGCGGCCGCCAGCAGCAAGCATGACTTGTCCAGCCTGCAGGTACTGCAGGTGGGCGGCGCCAAGCTTGTG
CCGGAAGCTGCGCGGCGCGTGATCGACAGCCTGGGCTGCACCCTGCAGCAGGTGTTTGGCATGGCCGAAGGCCTGGTCAA
CTACACCCGGCTGGATGATCCGGAGGAACTGATCGTGGCCTGCCAGGGCCGGCCGATCAGCCCGGACGACGAAGTGCGCG
TGGTCGATGACCACGACCAGCCGGTGGCTGAGGGCGAAGTTGGCCATCTGCTGACCCGCGGCCCGTACACCATCCGTGGT
TACCACAACGATGCGGTGGCCAACGCGCGCTCGTTCACCGACGATGGGTTCTACCGCACCGGTGACCGCGTGCAGCAGTT
GCCCGGCGGCTATCTGGTGGTGCAGGGCCGTGCCGGTGACCACATCAACCGGGCGGGCGAGAAAATCTCCGCCGAGGAGA
TTGAAGATCACCTGCTGGCCCACCCCGGCGTGTTCGACGCCGCCGTGGTCTCCATTCCCGATGAGTATCTCGGTGAGCGC
AGCTGCGCCTTCGTGATCCAGCAGGGGGAGCCGATCAAGGCACCGGCACTGAAGGCCTGGATGCGTACGCGCGGCCTGGC
GGCGTTCAAGGTGCCGGACCAGGTCGTGTTCGTCGACAGCTTCGATACCACCGCGGTCGGCAAGATCAGCCGCCGCGAAC
TGCGCGCGCAGCTGCGCGCGCGTCATCTGCAACAGACAGGAGGAACGCGCTGA

Protein sequence : 
MNTSIDSSRLPLKQVWPDALAARYREAGHWRGETFPAFLRERAERYADDIAVVAGDIRLSYAQLWHEAGRIGSGLLALGL
QPGERVLVQLGNTAGFITTVCGLFRAGLVPVYALPAHRITELVHFANKAEASAYITADLHDGFDHRGLARALQAEVPALR
HVVIDGDAAEFTALESLQGDRSQLPADPDPQSVAFLQISGGSTGLSKLIPRTHDDYIYSFRASNDICGIDRDSVYLVALP
AAHNFPMSSPGFFGALYAGARVVLSPGPGPDAAFPLIARERVTCCGLVPPLALLWAQAAASSKHDLSSLQVLQVGGAKLV
PEAARRVIDSLGCTLQQVFGMAEGLVNYTRLDDPEELIVACQGRPISPDDEVRVVDDHDQPVAEGEVGHLLTRGPYTIRG
YHNDAVANARSFTDDGFYRTGDRVQQLPGGYLVVQGRAGDHINRAGEKISAEEIEDHLLAHPGVFDAAVVSIPDEYLGER
SCAFVIQQGEPIKAPALKAWMRTRGLAAFKVPDQVVFVDSFDTTAVGKISRRELRAQLRARHLQQTGGTR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE CAA21394.1 - Virulence HPI Protein 2e-106 49
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 8e-105 49
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-106 49
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-104 49
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-106 49
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-106 49
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 2e-106 49
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-106 49
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-106 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Smal_2275 YP_002028661.1 AMP-dependent synthetase and ligase VFG0168 Protein 3e-116 51
Smal_2275 YP_002028661.1 AMP-dependent synthetase and ligase VFG1817 Protein 3e-109 48
Smal_2275 YP_002028661.1 AMP-dependent synthetase and ligase VFG0932 Protein 1e-103 46