Gene Information

Name : Ppha_2110 (Ppha_2110)
Accession : YP_002018934.1
Strain : Pelodictyon phaeoclathratiforme BU-1
Genome accession: NC_011060
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 2194770 - 2195906 bp
Length : 1137 bp
Strand : -
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: plt:Plut_1548 cystathionine gamma-synthase

DNA sequence :
ATGAGTTTTCAGACTGATACGATTCACGCCGGAGTTGGCCCGGATAAGGCATATGGCGCCATTATGACTCCGATTTACCA
GAGTTCAACCTTTGTTTTCGAGGATATCGGCAAACACAAGGGATTTGATTATACCCGCAGCGGAAACCCGACACGCAAGG
CGCTCGAAGATAACCTTTGCGCTCTTGAAGGCTGCTCATTTGCTGTAGCGGTGACAACTGGCATGGCGGCGATTACCTCG
ACCCTCAATATCTTTAAATCCGGCGACGAGATTATTTGTACCGATGACTGCTATGGAGGCACATCACGACTGATGAAGAC
GGTTGAGGAGCACTTCGGTATCACAGTACATTTTGTCAATCTTCAGGATGCGGCAAATCTTCTGCCCTATGTGAATGAGA
AGACAAAAGCGGTATGGGTTGAAACACCCTCCAATCCGCTGTTGAACCTGGTTGATATTGCCGCCGTGGGGGCACTTGCA
AAAGAGAGGGGTTTGTTGACCATTGTGGACAATACCTTTCTTTCGCCTTATGGTCAGAAGCCTTTCGAGCTTGGAGCTGA
TATTGTAGTGCATTCAACAACGAAGTACCTCAATGGCCATTCTGATGTGGTTGGTGGAGCAGTGCTGTCGAATAGTGAAG
AGCTCGATGCCCGTCTGAAGTTTATTGTCAATGCGCTTGGAACTTGCGCACAGCCCTTCGACTGCTGGCTGGTGCTTCGT
GGTATCAAGACGCTGGTGGTGCGCATGAGGGAGCATGAGCGCAATGCACAGGCTGTGGCCGAGTTTCTTGAGCAGCATGG
CAGAGTGAAGCGGGTTTTTTATCCCGGCCTTCCGGCTCATCCGCAGCATGAACTGGCTAAAAAACAGCAACGCTGTTTTG
GAGGAATGGTCTCTTTCGAGCTTGATGGTGGCATTGAGGATGTCAACCGTGTGCTGAAGGGAACAAAGCTCTTTGCACTT
GCTGAAAGCCTTGGCGGAGTTGAATCGCTGATTGAGCATCCGGCAACGATGAGCCATGCCTCAATGGATCGGGATCATCG
CGAGGCGGCAGGGATAACTGATACGGTCATCAGGCTTTCGGTTGGTATTGAAGATTGCGATGACCTTATTGAGGATTTGC
GGAGTGCACTTGGTTGA

Protein sequence :
MSFQTDTIHAGVGPDKAYGAIMTPIYQSSTFVFEDIGKHKGFDYTRSGNPTRKALEDNLCALEGCSFAVAVTTGMAAITS
TLNIFKSGDEIICTDDCYGGTSRLMKTVEEHFGITVHFVNLQDAANLLPYVNEKTKAVWVETPSNPLLNLVDIAAVGALA
KERGLLTIVDNTFLSPYGQKPFELGADIVVHSTTKYLNGHSDVVGGAVLSNSEELDARLKFIVNALGTCAQPFDCWLVLR
GIKTLVVRMREHERNAQAVAEFLEQHGRVKRVFYPGLPAHPQHELAKKQQRCFGGMVSFELDGGIEDVNRVLKGTKLFAL
AESLGGVESLIEHPATMSHASMDRDHREAAGITDTVIRLSVGIEDCDDLIEDLRSALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-76 44
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-77 44
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-62 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ppha_2110 YP_002018934.1 cystathionine gamma-synthase BAC0207 Protein 3e-64 41