Gene Information

Name : Ppha_2001 (Ppha_2001)
Accession : YP_002018830.1
Strain : Pelodictyon phaeoclathratiforme BU-1
Genome accession: NC_011060
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 2089589 - 2090725 bp
Length : 1137 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: cph:Cpha266_0732 cystathionine gamma-synthase

DNA sequence :
ATGCAGTTTGAAACCCTTGCCATTCATGACGGACAGGCTCCTGATCCCCATACAGGATCAGTAACCGTCCCTGTTTACCA
GGCCTCTACCTTCGAGCGTGCTGACCTGCAGCGTCACGGTGAGTTCTTCTATTCGAGAATCGGCAATCCGACGAGAGCGG
CGCTCGAATCAACCATCGCACTGCTTGAAAACGGTCGTTATGGCCTCGCCTTCGCCTCCGGAGTTGCCGCTACCCTGGCC
GCGCTCCAGGTGGTCAAACCCGGAGAGCATATTGTGGCAAGCAACGATATCTATGGGGGAAGTTACCGCATTTTTGAGCA
ACTCCTCCGTCCGCTGGGGGTCACAACAAGCTATGCAGAAAGTTCAGATACCGCGAGTTATAAGGCATGCATCACCCCGG
AAACCAGACTGATCTGGATTGAAACCCCGAGCAACCCGCTTCTTCAGCTCTCCGACATCCGCGCTCTTGCCTCACTGGCA
AAAGAGCGCGGCATCCTGCTCGCGGTCGACAACACCTTTTTAAGCCCCTACTTCCAGCGTCCGCTTGAACTTGGAGCCGA
TATTGTTGTCCACAGCACCACAAAATATCTTGGCGGGCACAGTGACGTCATCGGTGGCGCTGTCATCACCTCGGATGCAG
CGCTGCACACCATCATCAAAAACTATCAGGCCGCAGCGGGAGCCATACCGGCGCCCTGGGACTGCTGGCTCATTCTTCGT
GGATTGAAAACGCTTAAAATCCGCATGAAAGAGCATGAGGCAAACGCCCTGCATCTTGCCAAATTTCTTGAACAGCACCC
GGCAGTGGAGCAGGTTTTTTATCCAGGCCTCCCATCCCACCCGCAGCATGAGCTGGCGAAACAGCAGATGAGCGGGTTCG
GGGGAATGGTAACCTTTGCCCTTAAAGGGGGGCTTCCGGCTGTCGAACAACTGGTCGCACGAATCAAACTGTTTATCCTT
GCCGACAGCCTCGGCGGTGTAGAGTCGCTCATCGCATCACCGGCCAAAATGACACTCGGAGCCCTCTCGATTGAGGAGCG
TGCGCGGAGGAGATGTACCGACAACCTCGTACGCCTCTCTGTCGGGCTTGAAAATGCAGAGGATCTGGAGGCGGATTTGT
TGAACGCGATTACGTAA

Protein sequence :
MQFETLAIHDGQAPDPHTGSVTVPVYQASTFERADLQRHGEFFYSRIGNPTRAALESTIALLENGRYGLAFASGVAATLA
ALQVVKPGEHIVASNDIYGGSYRIFEQLLRPLGVTTSYAESSDTASYKACITPETRLIWIETPSNPLLQLSDIRALASLA
KERGILLAVDNTFLSPYFQRPLELGADIVVHSTTKYLGGHSDVIGGAVITSDAALHTIIKNYQAAAGAIPAPWDCWLILR
GLKTLKIRMKEHEANALHLAKFLEQHPAVEQVFYPGLPSHPQHELAKQQMSGFGGMVTFALKGGLPAVEQLVARIKLFIL
ADSLGGVESLIASPAKMTLGALSIEERARRRCTDNLVRLSVGLENAEDLEADLLNAIT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-75 45
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-76 45
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-65 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ppha_2001 YP_002018830.1 cystathionine gamma-synthase BAC0207 Protein 3e-64 44