Gene Information

Name : tpx (Ppha_1888)
Accession : YP_002018731.1
Strain : Pelodictyon phaeoclathratiforme BU-1
Genome accession: NC_011060
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 1977207 - 1977707 bp
Length : 501 bp
Strand : -
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGGCACAGATTACCTTCAAGGGCACTCCAGTTGAAACAGTCGGGACTCTTCCCGCCAAAGGTTCAGAAGCTCCTTTTTT
TTGTCTGGTGAAAACCGATCTCACCGAAGCCGGACCTGCTGATTTCGGAAGTAAAAGAATAGTTCTCAATATCTTTCCGA
GTCTTGATACGCCAGTCTGCGCTGCTTCAGTCAGGCAATTCAACAAGGAGGCTTCATCGCTCGACAATACGGTTGTGCTC
TGTATCTCCGCCGATTTGCCCTTTGCCCACAAACGTTTTTGTGAAACCGAGGGGTTGAAAAATGTTGTTTCGCTCTCCGT
TTTTCGCTCTCCCGAATTTGGTAGGGATTATGGTGTTACTCTTGCTACCGGCCCTCTGAAGGGGCTTCTTTCGCGCGCCA
TTGTTATTATTGATGCTGACGGGATCGTGCGCTACACCGAACAGGTGGCAGAAATTGTCGAAGAACCGGACTACAGTGCA
GCGCTCAAGGTTCTTGCGTAA

Protein sequence : 
MAQITFKGTPVETVGTLPAKGSEAPFFCLVKTDLTEAGPADFGSKRIVLNIFPSLDTPVCAASVRQFNKEASSLDNTVVL
CISADLPFAHKRFCETEGLKNVVSLSVFRSPEFGRDYGVTLATGPLKGLLSRAIVIIDADGIVRYTEQVAEIVEEPDYSA
ALKVLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 5e-32 44
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 3e-32 44
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 4e-32 44
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 2e-32 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_002018731.1 thiol peroxidase VFG0087 Protein 8e-33 44